{"brand":"Compound Laws","url":"https://compoundlaws.com/compounds/endomorphin-1/south-carolina/","compound":{"slug":"endomorphin_1","name":"Endomorphin-1","same_as":"https://en.wikipedia.org/wiki/Endomorphin"},"jurisdiction":{"code":"SC","name":"South Carolina"},"as_of":"2026-07-18","answer":"As of July 18, 2026, Endomorphin-1 is legal to sell at retail in South Carolina. Unscheduled; analog effect-prong reaches analgesics - human-consumption gate is the SOLE barrier (moderate residual risk). Controlling source: S.C. Code 44-53-110(7) (controlled substance analogue; effect prong INCLUDES 'analgesic'; human-consumption gate is the SOLE barrier).","forms":[{"form":"all","label":"All forms","status":"legal","state_status":null,"federal_overlay":false,"headline":"Unscheduled; analog effect-prong reaches analgesics - human-consumption gate is the SOLE barrier (moderate residual risk)","rule_type":"permanent","tier":"unscheduled","schedule_class":null,"limit":null,"effective_date":null,"verified_at":"2026-07-18","confidence":"confirmed","verbatim_excerpt":"S.C. Code 44-53-110(7): \"'Controlled substance analogue' means a substance that is INTENDED FOR HUMAN CONSUMPTION and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III OR has a stimulant, depressant, ANALGESIC, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include ... any substance for which there is an approved new drug application; or ... any substance if an exemption is in effect for investigational use ...\" [Disjunctive; effect prong includes 'analgesic'; SOLE barrier is the front-end 'intended for human consumption' gate - closest call in the country.]","excerpt_source_url":"https://www.scstatehouse.gov/code/t44c053.php","citations":[{"title":"S.C. Code 44-53-110(7) (controlled substance analogue; effect prong INCLUDES 'analgesic'; human-consumption gate is the SOLE barrier)","url":"https://www.scstatehouse.gov/code/t44c053.php","pinpoint":null,"publisher":"South Carolina Legislature","type":"statute","primary":true,"official":true},{"title":"S.C. Code 44-53-370 (offense)","url":"https://www.scstatehouse.gov/code/t44c053.php","pinpoint":null,"publisher":"South Carolina Legislature","type":"statute","primary":false,"official":true}],"history":[]}],"neighbors":[{"code":"GA","status":"legal"},{"code":"NC","status":"legal"}],"laws":[{"citation":"S.C. Code § 44-53-190(D) (Schedule I hallucinogens — enumerated, 4-HO-MET absent); S.C. Code § 44-53-110(7) (controlled substance analogue)","title":null,"official_url":"https://www.scstatehouse.gov/code/t44c053.php","source_label":"OFFICIAL","effective_date":null,"retrieved_date":"2026-06-19","text_hash":"2ac96b8e28ca164c94fa2b4735716c4337e73279501c10f692d6c909e05e95fb"},{"citation":"S.C. Code Ann. Sec. 44-53-110(7) & Sec. 44-53-370(a)(1)","title":"Controlled substance analogue definition and prohibited acts (analogue offense)","official_url":"https://www.scstatehouse.gov/code/t44c053.php","source_label":"OFFICIAL","effective_date":null,"retrieved_date":"2026-07-20","text_hash":"fcee94a41f3ee741ab3ba5290b92b34145cab17fac753c4d1f666ee4e6b0e130"}]}