As of October 22, 2026, 4-HO-MET (Metocin) is illegal to sell at retail in North Carolina. Schedule I (named + class). Listed as schedule 1, effective 2018-01-01. Controlling source: N.C. Gen. Stat. Sec. 90-89(3)(kk) - Schedule I (named) + (3)(nn) class.
Verified October 22, 2026 (llm review) · confidence: under_reviewNamed in N.C. Gen. Stat. 90-89(3)(kk) 4-hydroxy-MET AND substituted-tryptamine class 90-89(3)(nn). Mechanism: named + class. Official NC General Assembly PDF. Added S.L. 2018-44.
**Named entry** - "kk. 4-hydroxy-MET." - N.C. Gen. Stat. Sec. 90-89(3)(kk), https://www.ncleg.net/enactedlegislation/statutes/pdf/bysection/chapter_90/gs_90-89.pdf (OFFICIAL - NC General Assembly). **Structural class** - "nn. Substituted tryptamines. - Any compound, unless specifically excepted, specifically named in this schedule, or listed under a different schedule, structurally derived from 2-(1H-indol-3-yl)ethanamine (i.e., tryptamine) by mono- or di-substitution of the amine nitrogen with alkyl or alkenyl groups whether or not further substituted on the indole ring to any extent with any alkyl, alkoxy, halo, hydroxyl, or acetoxy groups." - N.C. Gen. Stat. Sec. 90-89(3)(nn). Same URL (OFFICIAL).
Among North Carolina's 4 neighbors, Georgia and Virginia are illegal; South Carolina and Tennessee are restricted.
Open the interactive map · Every compound in North Carolina
Federal gray area. 4-HO-MET (metocin) - not federally scheduled by name; Schedule I by the Federal Analogue Act when intended for human consumption Federal detail
2 instruments on file for this compound's framework in North Carolina; 1 of 1 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
0727c242f96d13b7**Named entry** — "kk. 4-hydroxy-MET." — N.C. Gen. Stat. § 90-89(3)(kk), https://www.ncleg.net/enactedlegislation/statutes/pdf/bysection/chapter_90/gs_90-89.pdf (OFFICIAL — NC General Assembly). **Structural class** — "nn. Substituted tryptamines. – Any compound, unless specifically excepted, specifically named in this schedule, or listed under a different schedule, structurally derived from 2-(1H-indol-3-yl)ethanamine (i.e., tryptamine) by mono- or di-substitution of the amine nitrogen with alkyl or alkenyl groups … whether or not further substituted on the indole ring to any extent with any alkyl, alkoxy, halo, hydroxyl, or acetoxy groups." — N.C. Gen. Stat. § 90-89(3)(nn). Same URL (OFFICIAL).
c4948c2dd9d2c11f(8) Substituted phenethylamines. - This includes any compound, unless specifically excepted, specifically named or included in another subset in this schedule, or listed under a different schedule, structurally derived from phenylethan-2-amine by substitution on the phenyl ring in any of the following ways, that is to say, by substitution with a fused methylenedioxy ring, fused furan ring, or fused tetrahydrofuran ring; by substitution with two alkoxy groups; by substitution with one alkoxy and either one fused furan, tetrahydrofuran, or tetrahydropyran ring system; or by substitution with two fused ring systems from any combination of the furan, tetrahydrofuran, or tetrahydropyran ring systems. Whether or not the compound is further modified in any of the following ways, that is to say: (i) by substitution of phenyl ring by any halo, hydroxyl, alkyl, trifluoromethyl, alkoxy, or alylthio groups, (ii) by substitution at the 2-position by any alkyl groups, or (iii) by substitution at the 2-amino nitrogen atom with alkyl, dialkyl, benzyl, hydroxybenzyl, methylenedioxybenzyl, or methoxybenzyl groups. Substances in this class include, but are not limited to: 2C-I (4-Iodo-2,5-dimethoxyphenethylamine), APDB ((2-aminopropyl)-2,3-dihydrobenzofuran), MBDB (3,4-methylenedioxy-N-methylbutanamine), and 2C-I-NBOH (N-(2-hydroxybenzyl)-4-iodo-2,5-dimethoxyphenethylamine).
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