Is 4-HO-MET (Metocin) Legal in South Carolina? (2026)

Instrument

statute

Source

https://www.scstatehouse.gov/code/t44c053.php

Retrieved

2026-06-19

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**§ 44-53-190(D) (hallucinogen chapeau)** — "(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:"
— S.C. Code § 44-53-190(D), https://www.scstatehouse.gov/code/t44c053.php (OFFICIAL — SC Legislature). The enumerated tryptamines are Bufotenine, DET, DMT, Psilocybin, Psilocyn only; 4-HO-MET is not present, and no tryptamine structural class exists in § 44-53-190.
**§ 44-53-110(7) (controlled substance analogue)** — "'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III."
— S.C. Code § 44-53-110(7), https://law.justia.com/codes/south-carolina/2022/title-44/chapter-53/section-44-53-110/ (MIRROR: Justia; canonical version identical).

Instrument

Controlled substance analogue definition and prohibited acts (analogue offense)

Source

https://www.scstatehouse.gov/code/t44c053.php

Retrieved

2026-07-20

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S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;