In South Carolina, Compound Laws tracks 19 compounds: 4 legal to sell at retail, 6 restricted, 2 in a gray area, 1 illegal, 1 not yet verified, and 5 whose status varies by product form. Verified through October 22, 2026.
2ac96b8e28ca164c**§ 44-53-190(D) (hallucinogen chapeau)** — "(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:" — S.C. Code § 44-53-190(D), https://www.scstatehouse.gov/code/t44c053.php (OFFICIAL — SC Legislature). The enumerated tryptamines are Bufotenine, DET, DMT, Psilocybin, Psilocyn only; 4-HO-MET is not present, and no tryptamine structural class exists in § 44-53-190. **§ 44-53-110(7) (controlled substance analogue)** — "'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III." — S.C. Code § 44-53-110(7), https://law.justia.com/codes/south-carolina/2022/title-44/chapter-53/section-44-53-110/ (MIRROR: Justia; canonical version identical).
8ee41eb7bdfae607[Pending bill text, House version of April 22, 2026, not law:] Sec. 2, 46-55-10(4): [consumable hemp product means a product] "intended for human consumption, ingestion, injection, or inhalation" [...] "Smokeable flower or prerolls are not considered a consumable hemp product and are prohibited from being sold in this State." Sec. 3, 46-55-70(D): ["direct shipments of consumable hemp products" into or within the State are prohibited; online sales and direct delivery are] "strictly prohibited". [Current 46-55 text not fetched.]
fcee94a41f3ee741S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;
6b22b88ab851d1cc44-53-2010 Definitions. (3) "Kratom" means any part of the tropical evergreen plant mitragyna speciosa. (5) "Kratom product" means any food or dietary ingredient ... that: (a) contains any part of the leaf of the plant mitragyna speciosa, either on its native leaf or extracted form; or (b) contains any kratom alkaloids or constituents, or synthesized metabolites of any kratom alkaloids or constituents. 44-53-2020 (A) It is unlawful for a kratom processor or kratom retailer to: (1) distribute, dispense, or sell any kratom product to any individual under twenty-one years of age; or (2) prepare, manufacture, distribute, dispense, or sell any kratom product that: (a) is adulterated with a dangerous non-kratom substance ...; (b) contains a poisonous or otherwise harmful non-kratom ingredient including ... any substance listed in Section 44-53-190, 210, 230, 250, or 270; (c) contains a fully synthetic alkaloid including, but not limited to, fully synthetic mitragynine, fully synthetic 7-hydroxymitragynine, or any other fully synthetically derived compound of the plant mitragyna speciosa; (d) [residual solvents > USP-NF]; or (e) [not properly labeled]. (B) [no display accessible to under-21]. 44-53-2030 Labels (ingredients; amount of mitragynine and 7-hydroxymitragynine; serving size; servings per container; vendor; precautionary statements; not-intended-to-treat; under-21 prohibition). 44-53-2040 Violations: civil penalty up to $1,000 first / $2,000 subsequent.
9d854f7718decbfcSECTION 46-55-10. Definitions. For the purposes of this chapter: (1) "Cannabidiol" or "CBD" means the compound by the same name derived from the hemp variety of the Cannabis sativa L. plant. (2) "Commercial sales' means the sale of hemp products in the stream of commerce, at retail, wholesale, and online. (3) "Commissioner" means the Commissioner of the South Carolina Department of Agriculture. (4) "Cultivating" means planting, watering, growing, and harvesting a plant or crop. (5) "Department" means the South Carolina Department of Agriculture. (6) "Federally defined THC level for hemp" means a delta-9 THC concentration of not more than 0.3 percent on a dry weight basis, or the THC concentration for hemp defined in 7 U.S.C. SECTION 5940, whichever is greater. (7) "Handling" means possessing or storing hemp for any period of time. "Handling" also includes possessing or storing hemp in a vehicle for any period of time other than during its actual transport from the premises of a licensed person to cultivate or process industrial hemp to the premises of another licensed person. "Handling" does not mean possessing or storing finished hemp products. (8) "Hemp" or "industrial hemp" means the plant Cannabis sativa L. and any part of that plant, including the nonsterilized seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with the federally defined THC level for hemp. Hemp shall be considered an agricultural commodity. (9) "Hemp products" means all products with the federally defined THC level for hemp derived from, or made by, processing hemp plants or hemp plant parts, that are prepared in a form available for commercial sale, including, but not limited to, cosmetics, personal care products, food intended for animal or human consumption, cloth, cordage, fiber, fuel, paint, paper, particleboard, plastics, and any product containing one or more hemp-derived cannabinoids, such as cannabidiol. Unprocessed or raw plant material, including nonsterilized hemp seeds, is not considered a hemp product. (10) "Licensee" means an individual or business entity possessing a license issued by the department under the authority of this chapter to cultivate, handle, or process hemp. (11) "Marijuana" has the same meaning as in Section 44-53-110 and does not include tetrahydrocannabinol in hemp or hemp products as defined herein. (12) "Processing" means converting an agricultural commodity into a marketable form. (13) "State plan" means the plan submitted by the department and approved by the Secretary of the United States Department of Agriculture pursuant to which the department regulates hemp production. (14) "THC" means tetrahydrocannabinol.
8afdafcfacd6c588"Federally defined THC level for hemp" means a delta-9 THC concentration of not more than 0.3 percent on a dry weight basis, or the THC concentration for hemp defined in 7 U.S.C. Section 5940, whichever is greater. "Hemp products" means all products with the federally defined THC level for hemp derived from, or made by, processing hemp plants or hemp plant parts, that are prepared in a form available for commercial sale, including, but not limited to, cosmetics, personal care products, food intended for animal or human consumption, cloth, cordage, fiber, fuel, paint, paper, particleboard, plastics, and any product containing one or more hemp-derived cannabinoids, such as cannabidiol. Unprocessed or raw plant material, including nonsterilized hemp seeds, is not considered a hemp product.
740adf8224b32618SECTION 46-55-30. Application of chapter. The provisions contained in this chapter do not apply to the possession, handling, transport, or sale of hemp products and extracts, including those containing hemp-derived cannabinoids, including CBD. Nothing in this chapter authorizes any person to violate any federal or state law or regulation.
8afdafcfacd6c588"Federally defined THC level for hemp" means a delta-9 THC concentration of not more than 0.3 percent on a dry weight basis, or the THC concentration for hemp defined in 7 U.S.C. Section 5940, whichever is greater. "Hemp products" means all products with the federally defined THC level for hemp derived from, or made by, processing hemp plants or hemp plant parts, that are prepared in a form available for commercial sale, including, but not limited to, cosmetics, personal care products, food intended for animal or human consumption, cloth, cordage, fiber, fuel, paint, paper, particleboard, plastics, and any product containing one or more hemp-derived cannabinoids, such as cannabidiol. Unprocessed or raw plant material, including nonsterilized hemp seeds, is not considered a hemp product.
Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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