Is 7-OH (7-Hydroxymitragynine) Legal in South Carolina? (2026)

Rule type

permanent

Tier

kcpa regulated

Effective

2025-07-11

What the record says

7-OH concentrate under the SC KCPA; NO concentration cap, so not cap-barred; banned only if FULLY synthetic; labeling + 21+ apply.

Controlling language, verbatim

It is unlawful for a kratom processor or kratom retailer to ... (2) ... sell any kratom product that: ... (c) contains a fully synthetic alkaloid including, but not limited to, fully synthetic mitragynine, fully synthetic 7-hydroxymitragynine, or any other fully synthetically derived compound of the plant mitragyna speciosa; ... (e) does not meet the labeling requirements ... (S.C. Code 44-53-2020(A))

Source of excerpt

Citations

No citation on file for this row yet.

Where 7-OH (7-Hydroxymitragynine) stands across the country

Among South Carolina's 2 neighbors, Georgia is restricted; North Carolina is legal.

Open the interactive map · Every compound in South Carolina

Federal posture

Not federally scheduled. 7-OH: not yet scheduled; DEA re-noticed Oct 14 (Schedule I above 1 mg/g or under 100:1 mitragynine ratio) on or after Nov 13 Federal detail

Pending deadlines

• 2026-08-01 · Federal · DEA temporary Schedule I order for 7-OH (above threshold) - effective on Federal Register publication (DEA NOI 2026-07-01)
• 2026-08-05 · Federal · DEA temporary Schedule I - 7-OH above a specified threshold (DEA-1570 / FR 2026-13580)
• 2026-11-13 · Federal · DEA temporary Schedule I: 7-OH above 1 mg/g or under 100:1 mitragynine ratio (re-notice) (DEA-1570 / FR 2026-20943)
• 2026-12-31 · SC · SC H.4641 - would add Schedule I for synthetically-derived mitragynine/7-OH (passed House 4/30/2026; Senate Medical Affairs) (H.4641)

Verbatim law on file for South Carolina

1 instrument on file for this compound's framework in South Carolina; 0 of 0 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

44-53-2010 Definitions. (3) "Kratom" means any part of the tropical evergreen plant mitragyna speciosa. (5) "Kratom product" means any food or dietary ingredient ... that: (a) contains any part of the leaf of the plant mitragyna speciosa, either on its native leaf or extracted form; or (b) contains any kratom alkaloids or constituents, or synthesized metabolites of any kratom alkaloids or constituents.
44-53-2020 (A) It is unlawful for a kratom processor or kratom retailer to: (1) distribute, dispense, or sell any kratom product to any individual under twenty-one years of age; or (2) prepare, manufacture, distribute, dispense, or sell any kratom product that: (a) is adulterated with a dangerous non-kratom substance ...; (b) contains a poisonous or otherwise harmful non-kratom ingredient including ... any substance listed in Section 44-53-190, 210, 230, 250, or 270; (c) contains a fully synthetic alkaloid including, but not limited to, fully synthetic mitragynine, fully synthetic 7-hydroxymitragynine, or any other fully synthetically derived compound of the plant mitragyna speciosa; (d) [residual solvents > USP-NF]; or (e) [not properly labeled]. (B) [no display accessible to under-21].
44-53-2030 Labels (ingredients; amount of mitragynine and 7-hydroxymitragynine; serving size; servings per container; vendor; precautionary statements; not-intended-to-treat; under-21 prohibition).
44-53-2040 Violations: civil penalty up to $1,000 first / $2,000 subsequent.

Related

7-OH (7-Hydroxymitragynine) in neighboring states

• 7-OH (7-Hydroxymitragynine) in Georgia Restricted
• 7-OH (7-Hydroxymitragynine) in North Carolina Legal

7-OH (7-Hydroxymitragynine) in other states

Same framework in South Carolina

• Mitragynine Pseudoindoxyl in South Carolina Illegal
• Kratom (Whole Leaf / Mitragynine) in South Carolina Restricted
• Speciociliatine in South Carolina Restricted

Other compounds in South Carolina

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