Is Kanna (Sceletium tortuosum) Legal in South Carolina? (2026)

Legal

As of November 12, 2026, Kanna (Sceletium tortuosum) is legal to sell at retail in South Carolina. Not scheduled or named in South Carolina law; no kanna-specific statute or regulation. Controlling source: S.C. Code 44-53-190(D) (Schedule I hallucinogenic substances).

Verified November 12, 2026 (hash check) · confidence: confirmed

Is Kanna Legal? Every state and federal law

QuietNo pending legislation, deadlines or enforcement actions on file for Kanna in South Carolina.
Rule type
permanent
Tier
Unscheduled

What the record says

South Carolina Schedule I hallucinogenic substances (S.C. Code 44-53-190(D)) is a closed numbered list whose only botanical entries are peyote and marijuana; kanna is not listed there or in Schedules II to V of Chapter 53. A full-text sweep of every chapter of the South Carolina Code of Laws (all 63 titles, 1,319 chapter pages on scstatehouse.gov) and every chapter of the South Carolina Code of Regulations (all chapter PDFs, including the Department of Public Health chapter 61 volumes) for kanna, Sceletium, mesembrine, kougoed found no provision. The South Carolina Kratom Consumer Protection Act (2025 Act No. 53, S.221) and the hemp provisions of Title 46, Chapter 55 do not mention kanna, Sceletium or mesembrine. The Department of Public Health may add substances to the schedules under 44-53-160; its online schedule page could not be text-read (script-rendered), so the statutory list is the record. No kava- or kanna-specific food, labeling, age or licensing rule was found. Neither the plant nor its alkaloids are federally controlled; FDA food and supplement law applies (see the federal page).

Controlling language, verbatim

(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation: 1. 3,4-methylenedioxy amphetamine 2. 5-methoxy-3,4-methylenedioxy amphetamine 3. 3,4-methylenedioxymethamphetamine (MDMA) 4. 3,4,5-trimethoxy amphetamine 5. Bufotenine 6. Diethyltryptamine (DET) 7. Dimethyltryptamine (DMT) 8. 4-methyl-2,5-dimethoxyamphetamine (STP) 9. Ibogaine 10. Lysergic acid diethylamide (LSD) 11. Marijuana 12. Mescaline 13. Peyote

Source of excerpt

Citations

  1. S.C. Code 44-53-190(D) (Schedule I hallucinogenic substances) (South Carolina Legislature, 2026-10-28) PRIMARYOFFICIAL

Where Kanna (Sceletium tortuosum) stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among South Carolina’s 2 neighbors, Georgia and North Carolina are legal, the same posture as South Carolina.

Open the interactive map · Every compound in South Carolina · Where Kanna is banned · Embed this map

Federal posture

Not federally scheduled. Not federally controlled; sold under FDA dietary supplement and food law Federal detail

Verbatim law on file for South Carolina

10 instruments on file for this compound’s framework in South Carolina; 1 of 1 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

DPH List of Substances for Inclusion in the S.C. Controlled Substances Act, Schedule I (hallucinogen and related entries) · Schedule I list, 5-MeO-DMT entryOFFICIAL
Instrument
Schedule I list, 5-MeO-DMT entry
Source
https://dph.sc.gov/sites/scdph/files/docs/Health/docs/BoardORders/ListOfSubstances.pdf
Retrieved
2026-11-06
Fingerprint
78e3e885b27cc31f
C. Any of the following opium derivatives, their salts, isomers, and salts of isomers, unless
specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is
possible within the specific chemical designation:

Alpha-ethyltryptamine (alpha-ET)
Alpha-methyltryptamine (AMT)
4-Bromo-2,5-dimethoxyphenethylamine (2C-B)
2-(4-Chloro-2,5-dimethoxyphenyl) ethanamine (2C-C)
Cyclohexamine (Ethylamine analog of phencyclidine, PCE)
2-(2,5-Dimethoxy-4-methylphenyl) ethanamine (2C-D)
2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine (2C-E)
2-(2,5-Dimethoxyphenyl) ethanamine (2C-H)
2-(4-Iodo-2,5-dimethoxyphenyl) ethanamine (2C-I)
2-(2,5-Dimethoxy-4-nitro-phenyl) ethanamine (2C-N)
2-(2,5-Dimethoxy-4-(n)-prophylphenyl) ethanamine (2C-P)
2-(4-ethylthio-2,5-dimethoxyphenyl) ethanamine (2C-T-2)
2-(4-ethylthio-2,5-dimethoxyphenyl) ethanamine (2C-T-4)
2,5-Dimethoxy-4-(n)propylthiophenethylamine (2C-T-7)
2,5-Dimethoxy-4-ethylamphetamine (DOE)
5-Iodo-2-aminoindane (5-IAI)
3-Methoxy-4,5-methylenedioxyamphetamine (MMDA)
5 Methoxy-N,N,Dimethyltryptamine (5-MeO-DMT)
5-Methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT)
3,4-Methylenedioxy-N-ethylamphetamine (MDEA)
Rolicyclidine (Pyrrolidine analog of phencyclidine ,PHP, PCPy)
Tenocyclidine(1-[1-(2-Thienyl)cyclohexyl]piperidine, TCP)
1-[1-(2-Thienyl)cyclohexyl]pyrrolidine (TCPy)
DPH List of Substances for Inclusion in the S.C. Controlled Substances Act, Schedule III (c) · Schedule III, depressants (agency listing)OFFICIAL
Instrument
Schedule III, depressants (agency listing)
Source
https://dph.sc.gov/sites/scdph/files/docs/Health/docs/BoardORders/ListOfSubstances.pdf
Retrieved
2026-10-31
Fingerprint
eb2bdcce1769b918
(c) Unless specifically excepted or unless listed in another schedule, any material, compound,
mixture, or preparation which contains any quantity of the following substances having a
depressant effect on the central nervous system:

Embutramide
Ketamine
Sulfonmethane
Tiletamine & Zolazepam Combination Product
S.C. Code § 44-53-190(D) · Schedule I hallucinogenic substances (official text)OFFICIAL
Instrument
Schedule I hallucinogenic substances (official text)
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-11-01
Fingerprint
1cdc8becb99f8226
(7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III

(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:
Show 7 more laws on file
S.C. Code 44-53-110(7) · Controlled substance analogue definitionOFFICIAL
Instrument
Controlled substance analogue definition
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-11-01
Fingerprint
92bc675c0fcef463
(7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355.
S.C. Code 44-53-110(7) and 44-53-370(a)-(b)(2) · Controlled substance analogue definition and prohibited actsOFFICIAL
Instrument
Controlled substance analogue definition and prohibited acts
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-11-06
Fingerprint
9dc8094ce892ad23
(7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355.

(a) Except as authorized by this article it shall be unlawful for any person:

	(1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;

	(2) to create, distribute, dispense, deliver, or purchase, or aid, abet, attempt, or conspire to create, distribute, dispense, deliver, or purchase, or possess with intent to distribute, dispense, deliver, or purchase a counterfeit substance.

	(b) A person who violates subsection (a) with respect to:

	(1) a controlled substance classified in Schedule I (B) and (C) which is a narcotic drug or lysergic acid diethylamide (LSD) and in Schedule II which is a narcotic drug is guilty of a felony and, upon conviction, for a first offense must be imprisoned not more than fifteen years or fined not more than twenty-five thousand dollars, or both. For a second offense, the offender must be imprisoned not less than five years nor more than thirty years, or fined not more than fifty thousand dollars, or both. For a third or subsequent offense, the offender must be imprisoned not less than ten years nor more than thirty years, or fined not more than fifty thousand dollars, or both. Notwithstanding any other provision of law, a person convicted and sentenced pursuant to this item for a first offense or second offense may have the sentence suspended and probation granted and is eligible for parole, supervised furlough, community supervision, work release, work credits, education credits, and good conduct credits. Notwithstanding any other provision of law, a person convicted and sentenced pursuant to this subsection for a third or subsequent offense in which all prior offenses were for possession of a controlled substance pursuant to subsections (c) and (d), may have the sentence suspended and probation granted and is eligible for parole, supervised furlough, community supervision, work release, work credits, education credits, and good conduct credits. In all other cases, the sentence must not be suspended nor probation granted;

	(2) any other controlled substance classified in Schedule I, II, or III, flunitrazepam or a controlled substance analogue, is guilty of a felony and, upon conviction, for a first offense must be imprisoned not more than five years or fined not more than five thousand dollars, or both. For a second offense, the offender is guilty of a felony and, upon conviction, must be imprisoned not more than ten years or fined not more than ten thousand dollars, or both. For a third or subsequent offense, the offender is guilty of a felony and, upon conviction, must be imprisoned not less than five years nor more than twenty years, or fined not more than twenty thousand dollars, or both. Notwithstanding any other provision of law, a person convicted and sentenced pursuant to this item for a first offense or second offense may have the sentence suspended and probation granted, and is eligible for parole, supervised furlough, community supervision, work release, work credits, education credits, and good conduct credits. Notwithstanding any other provision of law, a person convicted and sentenced pursuant to this item for a third or subsequent offense in which all prior offenses were for possession of a controlled substance pursuant to subsections (c) and (d), may have the sentence suspended and probation granted, and is eligible for parole, supervised furlough, community supervision, work release, work credits, education credits, and good conduct credits. In all other cases, the sentence must not be suspended nor probation granted;
S.C. Code 44-53-190(D) · Schedule I: hallucinogenic substancesOFFICIAL
Instrument
Schedule I: hallucinogenic substances
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-10-29
Fingerprint
a0342a4df60ee965
	(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

	1. 3,4-methylenedioxy amphetamine

	2. 5-methoxy-3,4-methylenedioxy amphetamine

	3. 3,4-methylenedioxymethamphetamine (MDMA)

	4. 3,4,5-trimethoxy amphetamine

	5. Bufotenine

	6. Diethyltryptamine (DET)

	7. Dimethyltryptamine (DMT)

	8. 4-methyl-2,5-dimethoxyamphetamine (STP)

	9. Ibogaine

	10. Lysergic acid diethylamide (LSD)

	11. Marijuana

	12. Mescaline

	13. Peyote

	14. N-ethyl-3-piperidyl benzilate

	15. N-methyl-3-piperidyl benzilate

	16. Psilocybin

	17. Psilocyn

	18. Tetrahydrocannabinol (THC)

	19. 2,5-dimethoxyamphetamine

	20. 4-bromo-2,5-dimethoxyamphetamine

	21. 4-Methoxyamphetamine

	22. Thiophene analog of phencyclidine

	23. Parahexyl

	24. Synthetic cannabinoids.—Any material, compound, mixture, or preparation that is not listed as a controlled substance in Schedule I through V, is not an FDA-approved drug, and contains any quantity of the following substances, their salts, isomers (whether optical, positional, or geometric), homologues, and salts of isomers and homologues, unless specifically excepted, whenever the existence of these salts, isomers, homologues, and salts of isomers and homologues is possible within the specific chemical designation:

	a. Naphthoylindoles. Any compound containing a 3-(1-naphthoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-015, JWH-018, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, JWH-210, JWH-398, AM-2201, WIN 55-212, AM-2201 (C1 analog), AM-1220.

	b. Naphthylmethylindoles. Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

	c. Naphthoylpyrroles. Any compound containing a 3-(1-naphthoyl)pyrrole structure with substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-307, JWH-370, JWH-176.

	d. Naphthylmethylindenes. Any compound containing a naphthylideneindene structure with substitution at the 3-position of the indene ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.

	e. Phenylacetylindoles. Any compound containing a 3-phenylacetylindole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, SR-18, RCS-8, JWH-203, JWH-250, JWH-251.

	f. Cyclohexylphenols. Any compound containing a 2-(3-hydroxycyclohexyl)phenol structure with substitution at the 5-position of the phenolic ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not substituted in the cyclohexyl ring to any extent. Including, but not limited to, CP 47,497 (and homologues), cannabicyclohexanol, CP-55, 940.

	g. Benzoylindoles. Any compound containing a 3-(benzoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, AM-694, Pravadoline (WIN 48,098), RCS-4, AM-630, AM-1241, AM-2233.

	h. 2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo [1,2,3-de]-1, 4-benzoxazin-6-yl]-1-napthalenylmethanone (WIN 55,212-2).

	i. 9-(hydroxymethyl)-6,6-dimethy l-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol 7370 (HU-210, HU-211).

	j. Adamantoylindoles. Any compound containing a 3-(1-adamantoyl)indole structure with substitution at the nitrogen atom of the indole ring by a alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring system to any extent.

	(E) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substance having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers if possible within the specific chemical designation:

	(1) Mecloqualone;

	(2) Methaqualone; or

	(3) Gamma Hydroxybutyric Acid.

	(F) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers, and salts of isomers:

	(1) Fenethylline;

	(2) N-ethylamphetamine;

	(3) Cathinone; or

	(4) Substituted Cathinones.

	Any compound (not being bupropion) structurally derived from 2-amino-1-phenyl-1-propanone by modification in any of the following ways:

	(a) by substitution in the phenyl ring to any extent with alkyl, alkoxy, alkylenedioxy, haloalkyl or halide substituents, whether or not further substituted in the phenyl ring by one or more other univalent substituents;

	(b) by substitution at the 3-position with an alkyl substituent;

	(c) by substitution at the nitrogen atom with alkyl or dialkyl groups, benzyl or methoxybenzyl groups; or

	(d) by inclusion of the nitrogen atom in a cyclic structure.

	Including, but not limited to: Methylone, Mephedrone, 3,4-Methylenedioxypyrovalerone (MDPV), Butylone, Methedrone, 4-Methylethcathinone, Flephedrone, Pentylone, Pentedrone, Buphedrone.
S.C. Code 44-53-2510 to 44-53-2540 (2026 Act No. 194) · Article 25, Nitrous OxideOFFICIAL
Instrument
Article 25, Nitrous Oxide
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-10-31
Fingerprint
7ff2103919aabbf2
SECTION 44-53-2510.
 Definitions.

	As used in this article:

	(1) "Department" means the South Carolina Department of Public Health.

	(2) “Division” means the State Law Enforcement Division.

	(3) "Food" means any food, food product, food ingredient, dietary ingredient, dietary supplement, or beverage intended for human consumption.

	(4) "Nitrous oxide" means dinitrogen monoxide (N2O) and any compound, liquid, gas, or chemical that contains nitrous oxide whether compressed, liquified, or contained in a cartridge, cylinder, tank, canister, or other vessel.

	(5) “Nitrous oxide products” means a cartridge, cylinder, tank, or other container that contains nitrous oxide.

	(6) “Characterizing flavor” means a distinguishable taste or aroma described by reference to a fruit, candy, dessert, beverage, mint, menthol, or any other flavor or aroma.

	(7) “Flavored nitrous oxide product” means a nitrous oxide product that is labeled, advertised, marketed, or sold by reference to a characterizing flavor.

	(8) “Exempt entity” means:

	(a) a physician, dentist, veterinarian, hospital, clinic, or other licensed healthcare facility acting within the lawful scope of practice;

	(b) a licensed commercial food and beverage business that holds a valid South Carolina retail food establishment permit or food service permit and uses nitrous oxide solely for legitimate culinary or beverage preparation in the ordinary course of business;

	(c) an automotive business operating with a business license and with an authorized dealer or distributor agreement and having the primary purpose of providing automotive supplies and services and using nitrous oxide solely for a lawful automotive performance, testing, or competition purpose;

	(d) an industrial or manufacturing business operating with a business license using nitrous oxide solely for lawful industrial or manufacturing purposes;

	(e) an institute of higher education, laboratory, or research facility using nitrous oxide solely for scientific research or instruction; or

	(f) a governmental entity or emergency services agency acting within the scope of official duties.

	(9) "Sell" or "sale" means to sell, furnish, give, distribute, provide, deliver, offer for sale, or possess with intent to sell, furnish, give, distribute, provide, deliver, or offer for sale.

HISTORY: 2026 Act No. 194 (S.751), SECTION 1, eff May 18, 2026.

 SECTION 44-53-2520.
 Unlawful to sell or possess nitrous oxide; exemptions.

	(A) Except as provided in subsection (E), it is unlawful for an individual or a retailer to sell, furnish, give, distribute, or provide nitrous oxide or nitrous oxide products in this State.

	(B) Except as provided in subsection (E), it is unlawful for a person to possess nitrous oxide or a nitrous oxide product with the intent to sell or distribute in this State.

	(C) A person may not possess, sell, market, or represent nitrous oxide for recreational inhalation.

	(D)(1) It is unlawful for any person to sell, furnish, give, distribute, provide, deliver, offer for sale, or possess with intent to sell a flavored nitrous oxide product in this State.

	(2) A person engaged in the sale of nitrous oxide or nitrous oxide products made through the internet or other remote sales methods shall perform an age verification through an independent, third-party age verification service that compares information available from public records to the personal information entered by the individual during the ordering process that establishes the individual is eighteen years of age or older, and shall use a method of mailing, shipping, or delivery that requires the signature of a person at least eighteen years of age purchasing for an exempted use before nitrous oxide or a nitrous oxide product will be released to the purchaser, unless the internet or other remote sales methods employ the following protections to ensure age verification:

	(a) the customer creates an online profile or account with personal information including, but not limited to, name, address, social security information, and a valid phone number, and that personal information is verified through publicly available records; or

	(b) the customer is required to upload a copy of his government-issued identification in addition to a current photograph of the customer; and

	(c) delivery is made to the customer’s name and address.

	(E) Subsections (A) and (B) do not apply to the sale, distribution, or transfer of nitrous oxide or nitrous oxide products to an exempt entity or to an individual for the exempt entity's or individual’s lawful purpose, provided the seller complies with Section 44-53-2530. An individual who is over the age of eighteen may have the following lawful purpose:

	(1) for personal mechanical repair of automotive or recreational vehicles, provided the product was purchased from a licensed automotive business;

	(2) for home culinary use, limited to nonrefillable cartridges of not more than 8 grams per cartridge; or

	(3) for medical use, as prescribed by a medical doctor.

	(F) Each unlawful sale, delivery, distribution, or transfer constitutes a separate offense.

	(G)(1) A retailer must not sell to an individual purchasing for an excepted personal use more than a case per day. A case contains a maximum of twenty-four individual cartridges that contain 8 grams of nitrous oxide.

	(2) An automotive business operating with a business license and with an authorized dealer or distributor agreement may only sell containers of nitrous oxide when mixed with not less than one hundred parts per million of sulfur dioxide as a fuel additive for combustion engines to exempt individuals as described in subsection (E). Retailers may only sell to exempt entities either by delivery to a business address or by invoice to an exempted entity.

	(3) A tobacco retail establishment with the primary purpose of selling tobacco products, as defined in Section 16-17-501, is prohibited from selling nitrous oxide or nitrous oxide products.

HISTORY: 2026 Act No. 194 (S.751), SECTION 1, eff May 18, 2026.

 SECTION 44-53-2530.
 Reasonable steps required to verify purchasers.

	(A) A person who sells or distributes nitrous oxide or nitrous oxide products pursuant to Section 44-53-2520(E) shall take reasonable steps to verify that the purchaser is an exempt entity or is using nitrous oxide or nitrous oxide products for an exempt purpose.

	(B) At a minimum, reasonable steps include obtaining and retaining:

	(1) the purchaser’s business name and business address or personal name and address;

	(2) a copy of, or the identifying number for, the purchaser’s applicable license, permit, or registration demonstrating exempt entity status, or an electronic copy of the person’s driver’s license or other government-issued identification; and

	(3) an invoice or receipt documenting the date of sale or transfer and the quantity and form of nitrous oxide or nitrous oxide products sold or transferred.

	(C)(1) Records required by this section must be retained for not less than two years and must be made available for inspection by the division or local law enforcement during normal business hours upon reasonable request.

	(2) The division may inspect premises during normal business hours for enforcement of this article.

	(D) The department may promulgate regulations in consultation with the division to administer and enforce the provisions of this article, including purchaser verification standards and recordkeeping requirements. Nothing in this article confers enforcement authority upon the department, and suspected violations shall be referred to appropriate law enforcement.

HISTORY: 2026 Act No. 194 (S.751), SECTION 1, eff May 18, 2026.

 SECTION 44-53-2540.
 Penalties; administrative sanctions.

	(A) A person who knowingly violates Section 44-53-2520 is guilty of a misdemeanor and, upon conviction:

	(1) for a first offense, must be fined not more than one thousand dollars or imprisoned for a term not to exceed six months, or both;

	(2) for a second offense, must be fined not more than five thousand dollars or imprisoned for a term not to exceed one year, or both; and

	(3) for a third or subsequent offense, must be fined not more than ten thousand dollars or imprisoned for a term not to exceed three years, or both.

	(B) In addition to criminal penalties, a business entity convicted of a violation of this article is subject to administrative action by the state or local authority that issued the business license, permit, or registration, including suspension or revocation, consistent with law.

HISTORY: 2026 Act No. 194 (S.751), SECTION 1, eff May 18, 2026.
S.C. Code Ann. 44-53-190(D) · Schedule I: hallucinogenic substancesOFFICIAL
Instrument
Schedule I: hallucinogenic substances
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-10-28
Fingerprint
2a390c0801ed2de3
(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

	1. 3,4-methylenedioxy amphetamine

	2. 5-methoxy-3,4-methylenedioxy amphetamine

	3. 3,4-methylenedioxymethamphetamine (MDMA)

	4. 3,4,5-trimethoxy amphetamine

	5. Bufotenine

	6. Diethyltryptamine (DET)

	7. Dimethyltryptamine (DMT)

	8. 4-methyl-2,5-dimethoxyamphetamine (STP)

	9. Ibogaine

	10. Lysergic acid diethylamide (LSD)

	11. Marijuana

	12. Mescaline

	13. Peyote

	14. N-ethyl-3-piperidyl benzilate

	15. N-methyl-3-piperidyl benzilate

	16. Psilocybin

	17. Psilocyn

	18. Tetrahydrocannabinol (THC)

	19. 2,5-dimethoxyamphetamine

	20. 4-bromo-2,5-dimethoxyamphetamine

	21. 4-Methoxyamphetamine

	22. Thiophene analog of phencyclidine

	23. Parahexyl
S.C. Code Ann. Sec. 44-53-110(7) & Sec. 44-53-370(a)(1) · Controlled substance analogue definition and prohibited acts (analogue offense)OFFICIAL
Instrument
Controlled substance analogue definition and prohibited acts (analogue offense)
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-07-20
Fingerprint
fcee94a41f3ee741
S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;
S.C. Code Sec. 44-53-190(D) · Schedule I, hallucinogenic substancesOFFICIAL
Instrument
Schedule I, hallucinogenic substances
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-10-31
Fingerprint
7fe194724b3a0ae9
(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

	1. 3,4-methylenedioxy amphetamine

	2. 5-methoxy-3,4-methylenedioxy amphetamine

	3. 3,4-methylenedioxymethamphetamine (MDMA)

	4. 3,4,5-trimethoxy amphetamine

	5. Bufotenine

	6. Diethyltryptamine (DET)

	7. Dimethyltryptamine (DMT)

	8. 4-methyl-2,5-dimethoxyamphetamine (STP)

	9. Ibogaine

	10. Lysergic acid diethylamide (LSD)

	11. Marijuana

	12. Mescaline

	13. Peyote

	14. N-ethyl-3-piperidyl benzilate

	15. N-methyl-3-piperidyl benzilate

	16. Psilocybin

	17. Psilocyn

	18. Tetrahydrocannabinol (THC)

	19. 2,5-dimethoxyamphetamine

	20. 4-bromo-2,5-dimethoxyamphetamine

	21. 4-Methoxyamphetamine

	22. Thiophene analog of phencyclidine

	23. Parahexyl

	24. Synthetic cannabinoids.—Any material, compound, mixture, or preparation that is not listed as a controlled substance in Schedule I through V, is not an FDA-approved drug, and contains any quantity of the following substances, their salts, isomers (whether optical, positional, or geometric), homologues, and salts of isomers and homologues, unless specifically excepted, whenever the existence of these salts, isomers, homologues, and salts of isomers and homologues is possible within the specific chemical designation:

	a. Naphthoylindoles. Any compound containing a 3-(1-naphthoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-015, JWH-018, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, JWH-210, JWH-398, AM-2201, WIN 55-212, AM-2201 (C1 analog), AM-1220.

	b. Naphthylmethylindoles. Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent.

	c. Naphthoylpyrroles. Any compound containing a 3-(1-naphthoyl)pyrrole structure with substitution at the nitrogen atom of the pyrrole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Including, but not limited to, JWH-307, JWH-370, JWH-176.

	d. Naphthylmethylindenes. Any compound containing a naphthylideneindene structure with substitution at the 3-position of the indene ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent.

	e. Phenylacetylindoles. Any compound containing a 3-phenylacetylindole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, SR-18, RCS-8, JWH-203, JWH-250, JWH-251.

	f. Cyclohexylphenols. Any compound containing a 2-(3-hydroxycyclohexyl)phenol structure with substitution at the 5-position of the phenolic ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not substituted in the cyclohexyl ring to any extent. Including, but not limited to, CP 47,497 (and homologues), cannabicyclohexanol, CP-55, 940.

	g. Benzoylindoles. Any compound containing a 3-(benzoyl)indole structure with substitution at the nitrogen atom of the indole ring by an alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl, or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Including, but not limited to, AM-694, Pravadoline (WIN 48,098), RCS-4, AM-630, AM-1241, AM-2233.

	h. 2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo [1,2,3-de]-1, 4-benzoxazin-6-yl]-1-napthalenylmethanone (WIN 55,212-2).

	i. 9-(hydroxymethyl)-6,6-dimethy l-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol 7370 (HU-210, HU-211).

	j. Adamantoylindoles. Any compound containing a 3-(1-adamantoyl)indole structure with substitution at the nitrogen atom of the indole ring by a alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring system to any extent.

Kanna (Sceletium tortuosum) in neighboring states

Kanna in 48 other states

Closest to Kanna in South Carolina

Same framework in South Carolina

22 other compounds in South Carolina

Cite this page

Compound Analytics. "Is Kanna Legal in South Carolina? Updated Nov 2026." Compound Laws, https://compoundlaws.com/compounds/kanna/south-carolina/. Accessed November 13, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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