As of October 7, 2026, 5-MAPB is in a legal gray area (sold in practice, exposed to an interpretive ban theory) in South Carolina. Analog-exposed / gray (controlled substance analogue offense, distribution side). Controlling source: S.C. Code Ann. Sec. 44-53-110(7) (analogue definition) + Sec. 44-53-370(a)(1)/(b)(2) (operative offense).
Verified October 7, 2026 (manual) · confidence: confirmedANALOG-ACT reach, INTERPRETIVE. Not named and not captured by any structural class: verified against the OFFICIAL S.C. Code chapter 44-53 that there is no benzofuran, no aminopropyl, and no 'substituted phenethylamine' class (the cathinone class is keyed to the phenyl ring); MDMA/MDA are S.C. Schedule I (the structural anchor). Reach runs only through the controlled-substance-analogue definition (Sec. 44-53-110(7): substantially-similar structure OR substantially-similar CNS effect + intended for human consumption) deployed by the operative offense Sec. 44-53-370(a)(1) / penalty (b)(2) - which sit on the manufacture/distribute/PWID side, not bare possession. Loose zone: 5-MAPB is reachable only if a fact-finder concludes it is 'substantially similar' to Schedule I MDMA/MDA AND intended for human consumption, and only on the distribution/PWID side. SC AG posture: no AG opinion or enforcement action found that pushes this to a categorical/named ban, so it stays gray (not hardened to illegal). Correction vs seed: seed sourced the Sec. 110(7) analogue definition from a Justia mirror; re-pulled it and the Sec. 370(a)(1) offense verbatim from the OFFICIAL SC StateHouse code.
'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar ... it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase ... or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue
Among South Carolina's 2 neighbors, Georgia and North Carolina are illegal.
Open the interactive map · Every compound in South Carolina
Federal gray area. Unscheduled by name; Schedule I by Federal Analogue Act when intended for human consumption Federal detail
2 instruments on file for this compound's framework in South Carolina; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
2ac96b8e28ca164c**§ 44-53-190(D) (hallucinogen chapeau)** — "(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:" — S.C. Code § 44-53-190(D), https://www.scstatehouse.gov/code/t44c053.php (OFFICIAL — SC Legislature). The enumerated tryptamines are Bufotenine, DET, DMT, Psilocybin, Psilocyn only; 4-HO-MET is not present, and no tryptamine structural class exists in § 44-53-190. **§ 44-53-110(7) (controlled substance analogue)** — "'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III." — S.C. Code § 44-53-110(7), https://law.justia.com/codes/south-carolina/2022/title-44/chapter-53/section-44-53-110/ (MIRROR: Justia; canonical version identical).
fcee94a41f3ee741S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;
Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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