As of October 22, 2026, 5-MAPB is in a legal gray area (sold in practice, exposed to an interpretive ban theory) in Colorado. Analog-exposed - in-schedule analog catch-all (C.R.S. 18-18-203(2)(g)). Controlling source: C.R.S. Sec. 18-18-203(2)(g) - Schedule I in-schedule controlled substance analog; MDMA/MDA listed anchors at (2)(c).
Verified October 22, 2026 (hash check) · confidence: confirmedMechanism: 5-MAPB is NOT named and no benzofuran appears in Schedule I. Reached by the in-schedule controlled-substance-analog catch-all C.R.S. 18-18-203(2)(g), which lists in Schedule I any analog whose structure is substantially similar to, or that was specifically designed to produce an effect substantially similar to/greater than, a substance listed in subsection (2), where intended for human consumption; MDMA (2)(c)(VII) and MDA (2)(c)(VI) are both listed anchors. Operative offense: C.R.S. 18-18-405 (generic Schedule I distribution/manufacture/possession-with-intent). The separate imitation-controlled-substances act 18-18-419/420 is appearance-based and NOT the hook. Basis INTERPRETIVE. Loose zone: whether a benzofuran is 'substantially similar' to MDMA/MDA or designed for a similar effect. Correction vs seed: none; re-verified (2)(g) verbatim on public.law (labeled mirror of the official leg.colorado.gov CRS Title 18 PDF). RENDER-DEBT: official PDF pull owed; mirror does not drive a hard illegal - status is restricted (analog), so mirror is acceptable.
Any material, compound, mixture, or preparation which is a controlled substance analog, the chemical structure of which is substantially similar to the chemical structure of a controlled substance listed in this subsection (2) or that was specifically designed to produce an effect substantially similar to or greater than the effect of a controlled substance listed in this subsection (2), all or part of which is intended for human consumption (C.R.S. 18-18-203(2)(g))
Among Colorado's 7 neighbors, Arizona and Nebraska are illegal; Kansas, New Mexico, Oklahoma and Utah are gray area; Wyoming is legal.
Open the interactive map · Every compound in Colorado
Federal gray area. Unscheduled by name; Schedule I by Federal Analogue Act when intended for human consumption Federal detail
3 instruments on file for this compound's framework in Colorado; 2 of 3 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
964bba3a8434c09d**Schedule gap — § 18-18-203(2)(c):** lists "(IV.5) 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT); … (VIII.5) Alpha-methyltryptamine (AMT); (IX) Bufotenine; (X) Diethyltryptamine; (XI) Dimethyltryptamine (DMT); … (XXI) Psilocybin; (XXII) Psilocyn." No 4-HO-MET; the catch-all reaches only "salts, isomers, and salts of isomers … theoretically possible within the specific chemical designation" (isomer = optical), which does not capture a homolog. **Analog provision — § 18-18-203(2)(g):** "Any material, compound, mixture, or preparation which is a controlled substance analog, the chemical structure of which is substantially similar to the chemical structure of a controlled substance listed in this subsection (2) or that was specifically designed to produce an effect substantially similar to or greater than the effect of a controlled substance listed in this subsection (2), all or part of which is intended for human consumption." **Analog definition — § 18-18-102(6)(a):** "'Controlled substance analog' means a substance the chemical structure of which is substantially similar to the chemical structure of a controlled substance in or added to schedule I or II and: (I) Which has a … hallucinogenic effect on the central nervous system substantially similar to … a controlled substance included in schedule I or II; or (II) … the individual represents or intends [it] to have a … hallucinogenic effect … substantially similar …" — C.R.S. § 18-18-203 and § 18-18-102; via labeled public.law mirror: https://colorado.public.law/statutes/crs_18-18-203 and https://colorado.public.law/statutes/crs_18-18-102
48a73c7b97b388de18-18-203. Schedule I. (1) A substance shall be added to schedule I by the general assembly when: (a) The substance has high potential for abuse; (b) The substance has no currently accepted medical use in treatment in the United States; and (c) The substance lacks accepted safety for use under medical supervision. (2) Unless specifically excepted by Colorado or federal law or Colorado or federal regulation or more specifically included in another schedule, the following controlled substances are listed in schedule I: (a) Any of the following synthetic opiates, including any isomers, esters, ethers, salts, and salts of isomers, esters, and ethers of them that are theoretically possible within the specific chemical designation: (I) Acetyl-alpha-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl ] -N- phenylacetamide); (II) Acetylmethadol; (III) Allylprodine; (IV) Alphacetylmethadol; Colorado Revised Statutes 2024 Page 687 of 783 Uncertified Printout (V) Alphameprodine; (VI) Alphamethadol; (VII) Alpha-methylfentanyl (N-[1-(alpha-methyl-beta-phenyl) ethyl-4-piperidyl] propionanilide; 1-(1-methyl-2-phenylethyl)- 4-(N-propanilido) piperidine); (VIII) Alpha-methylthiofentanyl (N-[1-methyl-2-(2-thienyl) ethyl-4-piperidinyl]-N- phenylpropanamide); (IX) Benzethidine; (X) Betacetylmethadol; (XI) Beta-hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4- piperidinyl]-N- phenylpropanamide); (XII) Beta-hydroxy-3-methylfentanyl (other name: N-[1-(2-hydroxy-2-phenethyl)-3- methyl-4-piperidinyl-] N-phenylpropanamide); (XIII) Betameprodine; (XIV) Betamethadol; (XV) Betaprodine; (XVI) Clonitazene; (XVII) Dextromoramide; (XVIII) Diampromide; (XIX) Diethylthiambutene; (XX) Difenoxin; (XXI) Dimenoxadol; (XXII) Dimepheptanol; (XXIII) Dimethylthiambutene; (XXIV) Dioxaphetyl butyrate; (XXV) Dipipanone; (XXVI) Ethylmethylthiambutene; (XXVII) Etonitazene; (XXVIII) Etoxeridine; (XXIX) Furethidine; (XXX) Hydroxypethidine; (XXXI) Ketobemidone; (XXXII) Levomoramide; (XXXIII) Levophenacylmorphan; (XXXIV) 3-methylfentanyl (N-[3-methyl-1-(2- phenylethyl)-4-piperidyl]-N- phenylpropanamide); (XXXV) 3-methylthiofentanyl (N-[3-methyl-1-(2- thienyl)ethyl-4-piperidinyl]-N- phenylpropanamide); (XXXVI) Morpheridine; (XXXVII) MPPP (1-methyl-4-phenyl-4-propionoxypiperidine); (XXXVIII) Noracymethadol; (XXXIX) Norlevorphanol; (XL) Normethadone; (XLI) Norpipanone; (XLII) Para-fluorofentanyl (N-(4-fluorophenyl)-N- [1-(2-phenethyl) -4-piperidinyl]- propanamide); Colorado Revised Statutes 2024 Page 688 of 783 Uncertified Printout (XLIII) PEPAP (1-(-2-phenethyl)-4-phenyl- 4-acetoxypiperidine); (XLIV) Phenadoxone; (XLV) Phenampromide; (XLVI) Phenomorphan; (XLVII) Phenoperidine; (XLVIII) Piritramide; (XLIX) Proheptazine; (L) Properidine; (LI) Propiram; (LII) Racemoramide; (LIII) Thiofentanyl (N-phenyl-N-[1-(2- thienyl) ethyl-4-piperidinyl]-propanamide); (LIV) Tilidine; (LV) Trimeperidine. (b) Any of the following opium derivatives, including their salts, isomers, and salts of isomers of them that are theoretically possible within the specific chemical designation: (I) Acetorphine; (II) Acetyldihydrocodeine; (III) Benzylmorphine; (IV) Codeine methylbromide; (V) Codeine-N-Oxide; (VI) Cyprenorphine; (VII) Desomorphine; (VIII) Dihydromorphine; (IX) Drotebanol; (X) Etorphine, except hydrochloride salt; (XI) Heroin; (XII) Hydromorphinol; (XIII) Methyldesorphine; (XIV) Methyldihydromorphine; (XV) Morphine methylbromide; (XVI) Morphine methylsulfonate; (XVII) Morphine-N-Oxide; (XVIII) Myrophine; (XIX) Nicocodeine; (XX) Nicomorphine; (XXI) Normorphine; (XXII) Pholcodine; (XXIII) Thebacon. (c) Any material, compound, mixture, or preparation containing any quantity of the following hallucinogenic substances, including any salts, isomers, and salts of isomers of them that are theoretically possible within the specific chemical designation: (I) 4-bromo-2, 5-dimethoxy-amphetamine (Some trade or other names: 4-bromo-2, 5- dimethoxy-alpha- methylphenethylamine; 4-bromo-2, 5-DMA.); (II) 2,5-dimethoxyamphetamine (Some trade or other names: 2,5-dimethoxy-alpha- methylphenethylamine; 2,5-DMA.); Colorado Revised Statutes 2024 Page 689 of 783 Uncertified Printout (II.5) 2,5-Dimethoxy-4-ethylamphetamine (DOET); (III) 4-methoxyamphetamine (Some trade or other names: 4-methoxy-alpha- methylphenethylamine; paramethoxyamphetamine, PMA.); (IV) 5-methoxy-3,4-methylenedioxy amphetamine; (IV.5) 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DiPT); (V) 4-methyl-2,5-dimethoxy-amphetamine (Some trade and other names: 4-methyl-2,5- dimethoxy-alpha- methylphenethylamine; DOM; and STP.); (VI) 3,4-methylenedioxy amphetamine; (VII) 3,4-methylenedioxymethamphetamine (MDMA); except that 3,4- methylenedioxymethamphetamine (MDMA) does not include a prescription drug product containing 3,4-methylenedioxymethamphetamine (MDMA) approved by the federal food and drug administration and placed on a schedule of the federal "Controlled Substances Act", 21 U.S.C. sec. 801 et seq., as amended, other than schedule I, or has been exempted from one or more provisions of such act, and that is intended for prescribed use and dispensed by a pharmacy or prescription drug outlet registered by the state of Colorado and only possessed by a person authorized to possess a controlled substance pursuant to section 18-18-302. Any such drug product containing MDMA that is approved by the federal food and drug administration must be controlled in Colorado in the same manner as required by any federal control designation pursuant to the federal "Controlled Substances Act", or any exemption from one or more provisions of that act, and subject to the provisions set forth in part 1 of article 280 of title 12 and part 3 of this article 18. Nothing in this section exempts a person from any violation of part 4 of this article 18. (VIII) 3,4,5-trimethoxy amphetamine; (VIII.5) Alpha-methyltryptamine (AMT); (IX) Bufotenine (Some trade and other names: 3-(beta-Dimethylaminoethyl)-5- hydroxyindole; 3-(2- dimethylaminoethyl)-5-indolol; N, N-dimethylserotonin; 5-hydroxy-N,N- dimethyltryptamine; mappine.); (X) Diethyltryptamine (Some trade or other names: N,N-Diethyltryptamine; DET.); (XI) Dimethyltryptamine (Some trade or other names: DMT.); (XII) Ibogaine (Some trade and other names: (7-Ethyl-6,6B,7,8,9,10,12,13-octahydro-2- methoxy-6,9-methano-5H-pyrido [1', 2':1,2] azepine [5,4- b] indole; Tabernanthe iboga.); (XIII) Lysergic acid diethylamide; (XIV) Mescaline; (XV) Parahexyl (Some trade or other names: 3-Hexyl-1-hydroxy-7,8,9,10-tetrahydro- 6,6,9- trimethyl-6H-dibenzo[b,d]pyran; Synhexyl.); (XVI) Peyote (Meaning all parts of the plant classified botanically as Lophophora williamsii Lemaire, whether growing or not, its seeds, any extract from any part of the plant, and every compound, salt, derivative, mixture, or preparation of the plant, or its seeds or extracts); (XVII) N-ethyl MDA; (XVIII) N-ethyl-3-piperidyl benzilate; (XIX) N-hydroxy MDA; (XX) N-methyl-3-piperidyl benzilate; (XXI) Psilocybin; (XXII) Psilocyn; (XXIII) Tetrahydrocannabinols; Colorado Revised Statutes 2024 Page 690 of 783 Uncertified Printout (XXIV) Ethylamine analog of phencyclidine (Some trade or other names: N-ethyl-1- phenylcyclohexylamine, (1-phenylcyclohexyl) ethylamine, N-(1-phenylcyclohexl) ethylamine, cyclohexamine, PCE.); (XXV) Pyrrolidine analog of phencyclidine (Some trade or other names: 1-(1- phenylcyclohexyl)- pyrrolidine, PCPy, PHP.); (XXVI) Thiophene analog of phencyclidine (Some trade or other names: 1-]1-(2- thienyl)-cyclohexyl- piperidine, 2-thienyl analog of phencyclidine, TPCP, TCP.); (XXVII) TCPy. (d) Any material, compound, mixture, or preparation containing any quantity of the following substances having a depressant effect on the central nervous system, including any salts, isomers, and salts of isomers of them that are theoretically possible within the specific chemical designation: (I) Mecloqualone; (II) Methaqualone. (e) Any material, compound, mixture, or preparation containing any quantity of the following substances having a stimulant effect on the central nervous system, including their salts, isomers, and salts of isomers: (I) Repealed. (II) Fenethylline; (III) Methcathinone; (IV) N-ethylamphetamine; (V) (+) Cis-4-methylaminorex; (VI) N,N-dimethylamphetamine. (f) Any material, compound, mixture, or preparation containing any quantity of gamma hydroxybutyrate [GHB], including its salts, isomers, and salts of isomers. (g) Any material, compound, mixture, or preparation which is a controlled substance analog, the chemical structure of which is substantially similar to the chemical structure of a controlled substance listed in this subsection (2) or that was specifically designed to produce an effect substantially similar to or greater than the effect of a controlled substance listed in this subsection (2), all or part of which is intended for human consumption. (h) Any material, compound, mixture, or preparation containing any quantity of N- benzylpiperazine (BZP), including its salts, isomers, and salts of isomers. Source: L. 92: Entire article R&RE, p. 332, § 1, effective July 1. L. 94: (2)(c)(II.5) added and (2)(e) amended, pp. 1721, 1722, §§ 20, 21, effective July 1. L. 96: (2)(e)(I), (2)(e)(III), and (2)(e)(V) amended, p. 1843, § 8, effective July 1. L. 2001: (2)(f) and (2)(g) added, pp. 858, 860, §§ 3, 9, effective July 1. L. 2005: (2)(c)(IV.5) and (2)(c)(VIII.5) added, p. 1501, § 7, effective July 1, 2006. L. 2009: (2)(h) added, (HB 09-1157), ch. 342, p. 1795, § 1, effective July 1. L. 2012: (2)(e)(I) repealed, (HB 12-1310), ch. 268, p. 1405, § 30, effective June 7. L. 2022: (2)(c)(VII) amended, (HB 22-1344), ch. 461, p. 3273, § 2, effective August 10. Editor's note: This section is similar to former § 12-22-309 as it existed prior to 1992. Cross references: For the legislative declaration in HB 22-1344, see section 1 of chapter 461, Session Laws of Colorado 2022. Colorado Revised Statutes 2024 Page 691 of 783 Uncertified Printout
145428adb15e2af0Any material, compound, mixture, or preparation which is a controlled substance analog, the chemical structure of which is substantially similar to the chemical structure of a controlled substance listed in this subsection (2) or that was specifically designed to produce an effect substantially similar to or greater than the effect of a controlled substance listed in this subsection (2), all or part of which is intended for human consumption.
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