Is Mitragynine Pseudoindoxyl Legal in Colorado? (2026)

Federal

Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) (effective 2026-08-26). State-law reading underneath: Restricted.

Rule type

permanent

Tier

concentration cap

Limit

2 % total alkaloids (percentage alkaloid fraction)

Effective

2025-08-13

Effectively prohibitive

Concentrate; semi-synthetic-alkaloid prohibition + 7-OH cap regime

Controlling language, verbatim

contains synthesized or semi-synthesized kratom alkaloids (SB25-072)

Source of excerpt

Citations

No citation on file for this row yet.

Change history

• 2026-09-23Status changed from illegal to restricted.
• 2026-09-23Status changed from restricted to illegal.

Where Mitragynine Pseudoindoxyl stands across the country

Among Colorado's 7 neighbors, Arizona, Kansas, Nebraska, New Mexico, Oklahoma, Utah and Wyoming are illegal, the same posture as Colorado.

Open the interactive map · Every compound in Colorado

Federal posture

Federally scheduled or prohibited. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) Federal detail

Pending deadlines

• 2026-08-01 · Federal · DEA temporary Schedule I order for mitragynine pseudoindoxyl, MGM-15, MGM-16 - effective on Federal Register publication (DEA NOI 2026-07-01)
• 2026-08-05 · Federal · DEA temporary Schedule I - mitragynine pseudoindoxyl, MGM-15, MGM-16 (DEA-1644 / FR 2026-17429)
  Second DEA Notice of Intent filed with the Federal Register on 7/1/2026 (companion to the 7-OH NOI, DEA-1570), placing three 7-OH-RELATED substances — mitragynine pseudoindoxyl (MP), MGM-15, and MGM-16 — into Schedule I under 21 U.S.C. 811(h). HHS confirmed these have no accepted medical use and a high potential for abuse. Same procedural clock as the 7-OH NOI: 30-day notice period, temporary order cannot issue before ~2026-08-05, effective on Federal Register publication of the order, 2-year duration (+1 yr possible). Unlike the 7-OH NOI there is NO concentration threshold here — these named substances are controlled outright. Confirm the exact companion docket number when the Federal Register posts on 7/6/2026.
• 2026-11-13 · Federal · DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice) (DEA-1570 / FR 2026-20943)
  On or after Nov 13, 2026 DEA intends to withdraw the Aug 26 order (FR 2026-17429) and place pseudoindoxyl in Schedule I only above a threshold: more than 1 mg/g or 1 mg/mL alone or combined with 7-OH, or mitragynine under 100 times the pseudoindoxyl or combined amount. Until then it stays Schedule I at any amount. MGM-15 and MGM-16 stay Schedule I unchanged (FR 2026-20942).

Verbatim law on file for Colorado

1 instrument on file for this compound's framework in Colorado; 0 of 0 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

6-1-737. Kratom - deceptive trade practice - definitions. (1) Definitions: "adulterated" = addition of fentanyl or any other controlled substance, a synthesized or semi-synthesized alkaloid, or another prohibited substance; "kratom product" = a food or dietary supplement that consists of or contains any part of a kratom leaf, a kratom leaf extract, or any kratom alkaloid/constituent/metabolite and does not include any synthesized or semi-synthesized alkaloids; "semi-synthesized alkaloid" = an alkaloid ... exposed to chemicals or processes that would confer a structural change ... such as oxidation, reduction, and ring opening and closing ...; "synthesized alkaloid" = created by chemical synthesis or biosynthetic means ... (2) A person shall not: (a) knowingly prepare, distribute, advertise, sell, or offer to sell a kratom product: (I) that is adulterated; (II) to a person under twenty-one years of age; (III) that contains a level of 7-hydroxymitragynine in the alkaloid fraction that is greater than two percent of the alkaloid composition of the kratom product; (IV) that is a confection; mimics a candy product; or is ... appealing to children ...; or (V) that is combustible or intended for vaporization; (b) [labeling requirements incl. quantitative declarations of mitragynine and 7-OH per serving]; (c) display/store accessible to under-21; or (d) manufacture/package/label/distribute a kratom product that: (I) contains synthesized or semi-synthesized alkaloids; or (II) has a level of 7-hydroxymitragynine in the alkaloid fraction greater than two percent of the alkaloid composition. (3) [violation = deceptive trade practice]. Companion: 18-13-132 (furnishing to under-21).

Related

Mitragynine Pseudoindoxyl in neighboring states

• Mitragynine Pseudoindoxyl in Arizona Illegal
• Mitragynine Pseudoindoxyl in Kansas Illegal
• Mitragynine Pseudoindoxyl in Nebraska Illegal
• Mitragynine Pseudoindoxyl in New Mexico Illegal
• Mitragynine Pseudoindoxyl in Oklahoma Illegal
• Mitragynine Pseudoindoxyl in Utah Illegal
• Mitragynine Pseudoindoxyl in Wyoming Illegal

Mitragynine Pseudoindoxyl in other states

Same framework in Colorado

• 7-OH (7-Hydroxymitragynine) in Colorado Restricted
• Kratom (Whole Leaf / Mitragynine) in Colorado Restricted
• Speciociliatine in Colorado Restricted

Other compounds in Colorado

Cite this page