Mitragynine Pseudoindoxyl Ban 2026: Every State Where It Is Illegal

Q: What states is Mitragynine Pseudoindoxyl illegal in?

Mitragynine Pseudoindoxyl is illegal to sell at retail in Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin and Wyoming as of November 12, 2026.

51 of 51 banned

As of November 12, 2026, Mitragynine Pseudoindoxyl is banned from retail sale in 51 of 51 US jurisdictions, and it is federally scheduled. Banned: Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin and Wyoming.

Ban here means retail sale is prohibited by statute, rule, order or scheduling. Restrictions and gray areas are listed on the compound page.

Record corrected November 3, 2026: Mitragynine Pseudoindoxyl in Georgia: Status now shown: Illegal. Change history

When does the next Mitragynine Pseudoindoxyl ban take effect?

Federal: DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice), Earliest Nov 13, 2026. DEA may act on or after this date. An order takes effect on publication with no grace period..

Hotearliest DEA action in 0 days (DEA-1570 / FR 2026-20943); notice of intent by the DEA (Drug Enforcement Administration), applies to every seller; enforcement action by the federal court (U.S. Attorney's Office, Northern District of Mississippi, with DEA), binds named parties only

Earliest Nov 13, 2026
DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice)
Federal · Enforcement date · DEA-1570 / FR 2026-20943
DEA may act on or after this date. An order takes effect on publication with no grace period.
active October 14, 2026
DEA re-notices intent to place 7-OH and mitragynine pseudoindoxyl above 1 mg/g (or 1 mg/mL) or below a 100:1 mitragynine ratio in Schedule I; withdraws July 2026 notice
Federal · Notice of intent · DEA-1570; FR Doc. 2026-20943 · DEA (Drug Enforcement Administration) · applies to every seller
Products exceeding 1 mg per gram (solids) or 1 mg per mL (liquids) of 7-OH alone or combined with pseudoindoxyl, or with a mitragynine-to-7-OH mass ratio under 100, would be Schedule I; the order cannot issue before 30 days after publication (on or after November 13, 2026) and would run two years.
active October 14, 2026
DEA notice of intent to issue a new temporary order keeping MGM-15 and MGM-16 in Schedule I without a threshold
Federal · Notice of intent · DEA-1644; FR Doc. 2026-20942 · DEA (Drug Enforcement Administration) · applies to every seller
DEA will issue a fresh two-year temporary order for MGM-15 and MGM-16 (no threshold) so they are separated from the thresholded pseudoindoxyl rule; the August 26, 2026 order stays in force until the new order publishes or expires August 26, 2028.
active October 1, 2026
Federal prosecutors charge an Oxford, Mississippi vape store clerk and his son with possession with intent to distribute after kratom-alkaloid pills tied to two Ole Miss student deaths tested for a DEA Schedule I compound
Mississippi · Enforcement action · Federal court (U.S. Attorney's Office, Northern District of Mississippi, with DEA) · binds named parties only
An informant bought kratom-based pills September 24, 2026; a DEA affidavit says a compound from the August 26, 2026 temporary scheduling order was listed as an ingredient; each defendant faces one count of possession with intent to distribute a controlled substance.
active August 26, 2026
DEA temporary scheduling order places mitragynine pseudoindoxyl, MGM-15 and MGM-16 in Schedule I for two years
Federal · Emergency rule · DEA-1644; 91 FR 54948; FR Doc. 2026-17429 · DEA (Drug Enforcement Administration) · applies to every seller
Mitragynine pseudoindoxyl, MGM-15 (dihydro-7-hydroxymitragynine) and MGM-16 (9-fluoro-dihydro-7-hydroxymitragynine), with isomers, esters, ethers and salts, became Schedule I effective August 26, 2026 through August 26, 2028; DOJ announced enforcement discretion for incidental trace pseudoindoxyl in botanical kratom.
active July 6, 2026
Notice of intent to temporarily schedule mitragynine pseudoindoxyl, MGM-15 and MGM-16
Federal · Notice of intent · FR 2026-13581 / 91 FR 40909 · DEA (U.S. Drug Enforcement Administration) · advisory, not binding
Order "will be published in the Federal Register on or after August 5, 2026" and takes effect on publication. This is the single highest-value watch item for pseudoindoxyl -- it would replace interpretive isomer capture in AL, AR, IN and WI with a NAMED federal basis. Speciociliatine is in NEITHER docket.
active June 22, 2026
Florida AG signs expanded emergency rule scheduling 7-OH and six related compounds (including pseudoindoxyl, MGM-15, MGM-16) as Schedule I above 1 mg/g or below a 100:1 mitragynine ratio
Florida · Emergency rule · Attorney General (Florida Attorney General James Uthmeier) · applies to every seller
Products may contain no more than 1 mg per gram (solids) or per mL (liquids) of 7-hydroxymitragynine, mitragynine pseudoindoxyl, 7-acetoxymitragynine, 9-hydroxycorynantheidine, 10-hydroxycorynantheidine, MGM-15 or MGM-16, and must contain at least 100 times more mitragynine by mass; violations are felony-level.
October 13, 2026
Schedules of Controlled Substances: Temporary Placement of MGM-15 and MGM-16 in Schedule I
Federal · Signal
final August 26, 2026
DOJ announces emergency scheduling of three 7-OH-related compounds and an enforcement-discretion policy for trace pseudoindoxyl in botanical kratom
Federal · Guidance · DEA (U.S. Department of Justice / Drug Enforcement Administration) · applies to every seller
DOJ stated it will exercise enforcement discretion where only incidental trace mitragynine pseudoindoxyl is confirmed in a product otherwise consistent with botanical kratom; the policy does not apply to MGM-15, MGM-16 or concentrated or added pseudoindoxyl and creates no legal exemption.
settled June 10, 2026
Relax Relief Rejuvenate (RRR) Trading settlement
Missouri · Settlement · Cole County · Attorney General (Missouri Attorney General) · binds named parties only
Enumerates 7-OH, MGM-15, mitragynine, mitragynine pseudoindoxyl and paynantheine -- notably NOT speciociliatine.

AKMEVT NH WA ID MT ND MN WIMINY MA RI OR NV WY SD IA IL IN OH PA NJ CTCA UT CO NE MO KY WV VA MD DEAZ NM KS AR TN NC SC DCOK LA MS AL GAHITXFL

BannedNot banned (legal, restricted or gray)Not yet verified

Federal

Federally scheduled or prohibited. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) Federal detail

States where Mitragynine Pseudoindoxyl is illegal (51)

Jurisdiction	Instrument	Effective	Basis
Alabama	Ala. Code 20-2-23 (Schedule I; items 322-323; subdivision (5) synthetic controlled substance analogue) and 20-2-20		federal precedence
Alaska	AS 11.71.120-11.71.125 (authority to schedule; emergency scheduling)		federal precedence
Arizona	A.R.S. 36-795.02 (kratom products; adulteration; 7-hydroxymitragynine level; synthetic alkaloids; sales to minors)		federal precedence
Arkansas	Ark. Dept. of Health List of Controlled Substances, Schedule I(c)(24)-(25), as filed Nov. 2015		federal precedence
California	Cal. Health & Safety Code 11401 (controlled substance analog; structure or effect prong)		federal precedence
Colorado	SB 25-072 (Daniel Bregger Act), enrolled, adding C.R.S. 6-1-740 and amending 18-13-132	2025-05-29	federal precedence
Connecticut	Conn. Gen. Stat. 21a-243(h) (2026 Supplement)	2026-08-26	federal precedence
Delaware	16 Del. C. 3001U-3002U (Kratom Consumer Protection Act)	2026-09-08	federal precedence
District of Columbia	D.C. Code 48-902.14 (controlled substance analogues)		federal precedence
Florida	Fla. emergency rule 2ER26-2 (Schedule I, s. 893.03(1)(a))		federal precedence
Georgia	O.C.G.A. 16-13-21(4) and 16-13-30 (Georgia Controlled Substances Act)	2026-08-26	federal precedence
Hawaii	Hawaii NED Emergency Controlled Substance Scheduling Action (Sept. 22, 2026), amending HRS 329-14(b)	2026-09-22	federal precedence
Idaho	Idaho Code 37-2702 and 37-2705 (Uniform Controlled Substances Act: authority to control; Schedule I)		federal precedence
Illinois	720 ILCS 570/201 Illinois Controlled Substances Act (authority; federal scheduling)		federal precedence
Indiana	IC 35-31.5-2-321 'Synthetic drug' (names 7-hydroxymitragynine and mitragynine, including an analog of the compound)		federal precedence
Iowa	Iowa Code 124.201(4) (federal designation of new controlled substances)		federal precedence
Kansas	HB 2365 (2026) enrolled, amending K.S.A. 21-5701 and 65-4105 (adds 7-hydroxymitragynine to Schedule I)		federal precedence
Kentucky	902 KAR 55:015 Section 1 (Schedule I)	2026-08-26	federal precedence
Louisiana	LAC 46:LIII.2704 Added Controlled Dangerous Substances (Declaration of Emergency)	2026-09-18	federal precedence
Maine	17-A M.R.S. 1102 (Schedules W, X, Y and Z)		federal precedence
Maryland	Md. Code, Crim. Law 5-202(f) (federal designation; similarly controlled unless the Department objects)	2026-08-26	federal precedence
Massachusetts	105 CMR 726.000, Temporary placement of kratom in schedule 1 (emergency regulation)	2026-08-28	federal precedence
Michigan	MCL 333.7204 (federal designation; similar scheduling; 60-day board meeting)		federal precedence
Minnesota	Minn. Stat. 152.02, subd. 12 (coordination with federal law; discretionary temporary order)		federal precedence
Mississippi	Miss. HB 1077 (2025 Reg. Sess.), Sections 1 and 2 (kratom product definition; synthesized-alkaloid exclusion; 1% / 0.5 mg 7-OH cap; 21+; registration)	2025-07-01	federal precedence
Missouri	19 CSR 30-1.002(1)(A)7. emergency amendment, Missouri Register Vol. 51 No. 20	2026-09-25	federal precedence
Montana	MCA 50-32-203 (effect of rescheduling under federal law)		federal precedence
Nebraska	Neb. Rev. Stat. 71-3802 (Kratom Consumer Protection Act definitions)		federal precedence
Nevada	NRS 453.2182 (treatment of federally scheduled substances)		federal precedence
New Hampshire	RSA 318-B:1-a, V		federal precedence
New Jersey	NJ Director non-objection and Schedule I inclusion: Kratom-related Substances	2026-09-25	federal precedence
New Mexico	NMSA 1978 30-31-2(U) (controlled substance analog) and 30-31-22 (distribution), Laws 2021 (1st S.S.), ch. 4 (HB 2), Sections 63 and 67		federal precedence
New York	N.Y. Public Health Law 1399-xx (sale or distribution of kratom products to minors)	2026-06-17	federal precedence
North Carolina	N.C. Gen. Stat. 90-88 (authority to control)		federal precedence
North Dakota	N.D. Cent. Code 19-03.1-05(3)(lll) (Schedule I, kratom alkaloid derivatives)	2026-09-04	federal precedence
Ohio	Ohio Adm. Code 4729:9-1-01.1 Mitragynine-related compounds (Schedule I, permanent rule eff. 2026-05-19)	2025-12-12	federal precedence
Oklahoma	63 O.S. 2-101(11) Definition of controlled dangerous substance (includes substances listed temporarily as federally controlled)	2026-08-26	federal precedence
Oregon	ORS 475.005(6) and 475.035 Definition of controlled substance; Board of Pharmacy authority to control by rule		federal precedence
Pennsylvania	35 P.S. 780-102 (designer drug) and 780-113(a)(36) (designer drug offense)		federal precedence
Rhode Island	R.I. Gen. Laws 21-28-2.01(c) Federal designation controlled after 60 days unless the director objects	2026-10-25	federal precedence
South Carolina	S.C. Dept. of Public Health order: Placement of Three 7-Hydroxymitragynine Related Substances in Schedule I (Sept. 25, 2026)	2026-09-25	federal precedence
South Dakota	SDCL 34-20B-115.1 Kratom: prohibited products, labeling		federal precedence
Tennessee	Tenn. Pub. Ch. 950 (2026), Sec. 2 (H.B. 1649), Matthew Davenport’s Law	2026-07-01	federal precedence
Texas	Texas Health and Safety Code Sec. 481.034		federal precedence
Utah	Utah Code 58-37-108(2)(a)(viii), 58-37-406, 58-37-107	2026-05-06	federal precedence
Vermont	Vermont Department of Health, Regulated Drug Rule (Ch. 8, Subch. 9), sections 3 and 7.0		federal precedence
Virginia	Va. Code 59.1-200(A)(77) (Virginia Consumer Protection Act, kratom products)	2026-07-01	federal precedence
Washington	RCW 69.50.101(15), (16); 69.50.201(d); 69.50.214; 69.50.401(1)		federal precedence
West Virginia	W. Va. Code 19-12F-3 (kratom act definitions)		federal precedence
Wisconsin	Wis. Stat. 961.01(4m), (12g); 961.11(4); 961.14(7)(mk)-(mL); 961.25		federal precedence
Wyoming	W.S. 35-7-2201 and 35-7-2202 (kratom product regulation)	2026-07-01	federal precedence

Recent bans

2026-11-03Georgia: Record corrected. Status now shown: Illegal.
2026-11-03Kentucky: Record corrected. Status now shown: Illegal.
2026-11-03Maryland: Record corrected. Status now shown: Illegal.
2026-11-03Missouri: Record corrected. Status now shown: Illegal.
2026-11-03Oklahoma: Record corrected. Status now shown: Illegal.
2026-11-03Rhode Island: Record corrected. Status now shown: Illegal.
2026-09-23Colorado: Status changed from restricted to illegal.
2026-09-23Arizona: Status changed from restricted to illegal.
2026-09-23Georgia: Status changed from restricted to illegal.
2026-09-23Kentucky: Status changed from restricted to illegal.

Mitragynine Pseudoindoxyl ban status by state

Is Mitragynine Pseudoindoxyl Legal? Every state · Mitragynine Pseudoindoxyl change history · All deadlines · What “illegal” means here

Cite this page

Compound Analytics. "Mitragynine Pseudoindoxyl Ban 2026: Every State Where It Is Illegal." Compound Laws, https://compoundlaws.com/bans/pseudoindoxyl/. Accessed November 13, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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