Is Mitragynine Pseudoindoxyl Legal in Ohio? (2026)

Federal

Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) (effective 2026-08-26). State-law reading underneath: Illegal.

Rule type

permanent

Tier

schedule i

Schedule

schedule 1

Effective

2025-12-12

Controlling language, verbatim

OAC 4729:9-1-01.1 schedules "Mitragynine-related compounds" incl. 7-hydroxymitragynine and mitragynine pseudoindoxyl as Schedule I; Mitragynine (4) and natural leaf/GRAS/FDA-approved forms exempt.

Source of excerpt

Citations

1. OAC 4729:9-1-01.1 Mitragynine-related compounds (permanent, eff. May 19, 2026) (Ohio Board of Pharmacy / LSC, 2026-10-07)OFFICIAL

Where Mitragynine Pseudoindoxyl stands across the country

Among Ohio's 5 neighbors, Indiana, Kentucky, Michigan, Pennsylvania and West Virginia are illegal, the same posture as Ohio.

Open the interactive map · Every compound in Ohio

Federal posture

Federally scheduled or prohibited. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) Federal detail

Pending deadlines

• 2026-08-01 · Federal · DEA temporary Schedule I order for mitragynine pseudoindoxyl, MGM-15, MGM-16 - effective on Federal Register publication (DEA NOI 2026-07-01)
• 2026-08-05 · Federal · DEA temporary Schedule I - mitragynine pseudoindoxyl, MGM-15, MGM-16 (DEA-1644 / FR 2026-17429)
  Second DEA Notice of Intent filed with the Federal Register on 7/1/2026 (companion to the 7-OH NOI, DEA-1570), placing three 7-OH-RELATED substances — mitragynine pseudoindoxyl (MP), MGM-15, and MGM-16 — into Schedule I under 21 U.S.C. 811(h). HHS confirmed these have no accepted medical use and a high potential for abuse. Same procedural clock as the 7-OH NOI: 30-day notice period, temporary order cannot issue before ~2026-08-05, effective on Federal Register publication of the order, 2-year duration (+1 yr possible). Unlike the 7-OH NOI there is NO concentration threshold here — these named substances are controlled outright. Confirm the exact companion docket number when the Federal Register posts on 7/6/2026.
• 2026-11-13 · Federal · DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice) (DEA-1570 / FR 2026-20943)
  On or after Nov 13, 2026 DEA intends to withdraw the Aug 26 order (FR 2026-17429) and place pseudoindoxyl in Schedule I only above a threshold: more than 1 mg/g or 1 mg/mL alone or combined with 7-OH, or mitragynine under 100 times the pseudoindoxyl or combined amount. Until then it stays Schedule I at any amount. MGM-15 and MGM-16 stay Schedule I unchanged (FR 2026-20942).

Verbatim law on file for Ohio

1 instrument on file for this compound's framework in Ohio; 1 of 1 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

The following are classified as schedule I controlled substances: (A) Mitragynine-related compounds, whether synthetic or naturally occurring substances contained in the plant, or in the resinous extractives of mitragyna speciosa (also known as kratom) and/or synthetic substances, derivatives, prodrugs, isomers, esters, ethers, salts and salts of isomers, esters and ethers with similar chemical structure. Mitragynine-related compounds include, but are not limited to, the following: 7-hydroxymitragynine; mitragynine pseudoindoxyl; dihydro-7-hydroxy mitragynine; and 7-acetoxymitragynine. Mitragynine-related compounds do not include any of the following: (1) Any dangerous drug that is the subject of an application approved by the [FDA] under subsections 505(c) or (j) of the [FD&C Act] ... for marketing as a dangerous drug; (2) Any compound used in food consistent with either: (a) A food additive regulation published in the [CFR]; or (b) A "no questions response" issued by the [FDA] in response to a [GRAS] notice. (3) Any drug approved by the [FDA] ... that may be lawfully sold over the counter without a prescription in accordance with section 505G of the [FD&C Act] ...; (4) Mitragynine.

Related

Mitragynine Pseudoindoxyl in neighboring states

• Mitragynine Pseudoindoxyl in Indiana Illegal
• Mitragynine Pseudoindoxyl in Kentucky Illegal
• Mitragynine Pseudoindoxyl in Michigan Illegal
• Mitragynine Pseudoindoxyl in Pennsylvania Illegal
• Mitragynine Pseudoindoxyl in West Virginia Illegal

Mitragynine Pseudoindoxyl in other states

Same framework in Ohio

• 7-OH (7-Hydroxymitragynine) in Ohio Illegal
• Kratom (Whole Leaf / Mitragynine) in Ohio Legal
• Speciociliatine in Ohio Gray area

Other compounds in Ohio

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