Is MGM-16 Legal in Ohio? (2026)

Instrument

Mitragynine-related compounds

Source

https://codes.ohio.gov/ohio-administrative-code/rule-4729:9-1-01.1

Retrieved

2026-11-08

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The following are classified as schedule I controlled substances:
Mitragynine-related compounds, whether synthetic or naturally occurring substances contained in the plant, or in the resinous extractives of mitragyna speciosa (also known as kratom) and/or synthetic substances, derivatives, prodrugs, isomers, esters, ethers, salts and salts of isomers, esters and ethers with similar chemical structure.
Mitragynine-related compounds include, but are not limited to, the following: 7-hydroxymitragynine; mitragynine pseudoindoxyl; dihydro-7-hydroxy mitragynine; and 7-acetoxymitragynine. Mitragynine-related compounds do not include any of the following:
(A) Any dangerous drug that is the subject of an application approved by the United States food and drug administration under subsections 505(c) or (j) of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355(c) or (j)) (December 12, 2025) for marketing as a dangerous drug;
(B) Any compound used in food consistent with either:
(1) A food additive regulation published in the United States Code of Federal Regulations; or
(2) A "no questions response" issued by the United States food and drug administration in response to a generally recognized as safe notice.
(C) Any drug approved by the United States food and drug administration that may be lawfully sold over the counter without a prescription in accordance with section 505G of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355h) (December 12, 2025).
(D) Mitragynine in vegetation form, including natural kratom leaf and ground natural kratom leaf, in accordance with Chapter 3715. of the Revised Code.

Instrument

OH Schedule I - Mitragynine-related compounds (7-OH + pseudoindoxyl NAMED; mitragynine exempt)

Source

https://codes.ohio.gov/ohio-administrative-code/rule-4729:9-1-01.1

Retrieved

2026-07-07

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629bd14f29d13383

The following are classified as schedule I controlled substances: (A) Mitragynine-related compounds, whether synthetic or naturally occurring substances contained in the plant, or in the resinous extractives of mitragyna speciosa (also known as kratom) and/or synthetic substances, derivatives, prodrugs, isomers, esters, ethers, salts and salts of isomers, esters and ethers with similar chemical structure. Mitragynine-related compounds include, but are not limited to, the following: 7-hydroxymitragynine; mitragynine pseudoindoxyl; dihydro-7-hydroxy mitragynine; and 7-acetoxymitragynine. Mitragynine-related compounds do not include any of the following: (1) Any dangerous drug that is the subject of an application approved by the [FDA] under subsections 505(c) or (j) of the [FD&C Act] ... for marketing as a dangerous drug; (2) Any compound used in food consistent with either: (a) A food additive regulation published in the [CFR]; or (b) A "no questions response" issued by the [FDA] in response to a [GRAS] notice. (3) Any drug approved by the [FDA] ... that may be lawfully sold over the counter without a prescription in accordance with section 505G of the [FD&C Act] ...; (4) Mitragynine.

Instrument

Effect of U.S. attorney general addition, transfer, or removal of substance from schedule

Source

https://codes.ohio.gov/ohio-revised-code/section-3719.43

Retrieved

2026-10-28

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When congress or, pursuant to the federal drug abuse control laws, the attorney general of the United States adds a compound, mixture, preparation, or substance to a schedule of the federal drug abuse control laws, transfers any of the same between one schedule of the federal drug abuse control laws to another, or removes a compound, mixture, preparation, or substance from the schedules of the federal drug abuse control laws, then such addition, transfer, or removal is automatically effected in the corresponding schedule or schedules established by rule adopted under section
3719.41
 of the Revised Code, subject to amendment pursuant to section
3719.44
 of the Revised Code.
The state board of pharmacy shall incorporate the addition, transfer, or removal into or from the schedules in its next update of the schedules under section
3719.41
 of the Revised Code.