Is 7-OH (7-Hydroxymitragynine) Legal in Ohio? (2026)

Rule type

permanent

Tier

schedule i

Schedule

schedule 1

Effective

2025-12-12

Controlling language, verbatim

OAC 4729:9-1-01.1 schedules "Mitragynine-related compounds" incl. 7-hydroxymitragynine and mitragynine pseudoindoxyl as Schedule I; Mitragynine (4) and natural leaf/GRAS/FDA-approved forms exempt.

Source of excerpt

Citations

1. OAC 4729:9-1-01.1 Mitragynine-related compounds (permanent, eff. May 19, 2026) (Ohio Board of Pharmacy / LSC, 2026-10-07)OFFICIAL

Where 7-OH (7-Hydroxymitragynine) stands across the country

Among Ohio's 5 neighbors, Indiana and Kentucky are illegal; West Virginia is restricted; Michigan and Pennsylvania are legal.

Open the interactive map · Every compound in Ohio

Federal posture

Not federally scheduled. 7-OH: not yet scheduled; DEA re-noticed Oct 14 (Schedule I above 1 mg/g or under 100:1 mitragynine ratio) on or after Nov 13 Federal detail

Pending deadlines

• 2026-08-01 · Federal · DEA temporary Schedule I order for 7-OH (above threshold) - effective on Federal Register publication (DEA NOI 2026-07-01)
• 2026-08-05 · Federal · DEA temporary Schedule I - 7-OH above a specified threshold (DEA-1570 / FR 2026-13580)
• 2026-11-13 · Federal · DEA temporary Schedule I: 7-OH above 1 mg/g or under 100:1 mitragynine ratio (re-notice) (DEA-1570 / FR 2026-20943)

Verbatim law on file for Ohio

1 instrument on file for this compound's framework in Ohio; 1 of 1 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

The following are classified as schedule I controlled substances: (A) Mitragynine-related compounds, whether synthetic or naturally occurring substances contained in the plant, or in the resinous extractives of mitragyna speciosa (also known as kratom) and/or synthetic substances, derivatives, prodrugs, isomers, esters, ethers, salts and salts of isomers, esters and ethers with similar chemical structure. Mitragynine-related compounds include, but are not limited to, the following: 7-hydroxymitragynine; mitragynine pseudoindoxyl; dihydro-7-hydroxy mitragynine; and 7-acetoxymitragynine. Mitragynine-related compounds do not include any of the following: (1) Any dangerous drug that is the subject of an application approved by the [FDA] under subsections 505(c) or (j) of the [FD&C Act] ... for marketing as a dangerous drug; (2) Any compound used in food consistent with either: (a) A food additive regulation published in the [CFR]; or (b) A "no questions response" issued by the [FDA] in response to a [GRAS] notice. (3) Any drug approved by the [FDA] ... that may be lawfully sold over the counter without a prescription in accordance with section 505G of the [FD&C Act] ...; (4) Mitragynine.

Related

7-OH (7-Hydroxymitragynine) in neighboring states

• 7-OH (7-Hydroxymitragynine) in Indiana Illegal
• 7-OH (7-Hydroxymitragynine) in Kentucky Illegal
• 7-OH (7-Hydroxymitragynine) in Michigan Legal
• 7-OH (7-Hydroxymitragynine) in Pennsylvania Legal
• 7-OH (7-Hydroxymitragynine) in West Virginia Restricted

7-OH (7-Hydroxymitragynine) in other states

Same framework in Ohio

• Mitragynine Pseudoindoxyl in Ohio Illegal
• Kratom (Whole Leaf / Mitragynine) in Ohio Legal
• Speciociliatine in Ohio Gray area

Other compounds in Ohio

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