Is Mitragynine Pseudoindoxyl Legal in Massachusetts? (2026)

Illegal

As of September 21, 2026, Mitragynine Pseudoindoxyl is illegal to sell (federally scheduled; state law on file reads illegal) in Massachusetts. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26). Controlling source: 105 CMR 726.000: Temporary placement of kratom in Schedule 1 pursuant to M.G.L. c. 94C, s. 2A (emergency regulation).

Verified September 21, 2026 · confidence: confirmed
Federal
Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) (effective 2026-08-26). State-law reading underneath: Illegal.
Rule type
emergency
Tier
schedule i
Effective
2026-08-28
Sunset
2027-08-28

Controlling language, verbatim

Kratom. The plant mitragyna speciosa, mitragynine, 7-hydroxymitragynine (also known as 7-OH), mitragynine pseudoindoxyl (also known as MP), dihydro-7-hydroxymitragynine (also known as MGM-15), 9-fluoro-7-hydroxymitragynine (also known as MGM-16), including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, whenever the existence of such isomers, esters, ethers, and salts is possible. Kratom includes any product held out or holding itself out to be kratom. [105 CMR 726.003] | Kratom is hereby placed in schedule 1 in accordance with M.G.L. c. 94C, § 2A. [105 CMR 726.004]

Source of excerpt

Citations

  1. 105 CMR 726.000: Temporary placement of kratom in Schedule 1 pursuant to M.G.L. c. 94C, s. 2A (emergency regulation) (Massachusetts Department of Public Health, 2026-09-22) PRIMARYOFFICIAL

Change history

  • Status changed from legal to illegal.
  • Tier changed from unscheduled to schedule_i.
  • Headline updated: "Schedule I. 105 CMR 726.003 names mitragynine pseudoindoxyl (MP). Also federal Schedule I since 2026-08-26".
  • Effective date changed from none to 2026-08-28.
  • Sunset date changed from none to 2027-08-28.

Where Mitragynine Pseudoindoxyl stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among Massachusetts's 5 neighbors, Connecticut, New Hampshire, New York, Rhode Island and Vermont are illegal, the same posture as Massachusetts.

Open the interactive map · Every compound in Massachusetts

Federal posture

Federally scheduled or prohibited. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) Federal detail

Pending deadlines

  • 2026-08-01 · Federal · DEA temporary Schedule I order for mitragynine pseudoindoxyl, MGM-15, MGM-16 - effective on Federal Register publication (DEA NOI 2026-07-01)
  • 2026-08-05 · Federal · DEA temporary Schedule I - mitragynine pseudoindoxyl, MGM-15, MGM-16 (DEA-1644 / FR 2026-17429)
    Second DEA Notice of Intent filed with the Federal Register on 7/1/2026 (companion to the 7-OH NOI, DEA-1570), placing three 7-OH-RELATED substances — mitragynine pseudoindoxyl (MP), MGM-15, and MGM-16 — into Schedule I under 21 U.S.C. 811(h). HHS confirmed these have no accepted medical use and a high potential for abuse. Same procedural clock as the 7-OH NOI: 30-day notice period, temporary order cannot issue before ~2026-08-05, effective on Federal Register publication of the order, 2-year duration (+1 yr possible). Unlike the 7-OH NOI there is NO concentration threshold here — these named substances are controlled outright. Confirm the exact companion docket number when the Federal Register posts on 7/6/2026.
  • 2026-11-13 · Federal · DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice) (DEA-1570 / FR 2026-20943)
    On or after Nov 13, 2026 DEA intends to withdraw the Aug 26 order (FR 2026-17429) and place pseudoindoxyl in Schedule I only above a threshold: more than 1 mg/g or 1 mg/mL alone or combined with 7-OH, or mitragynine under 100 times the pseudoindoxyl or combined amount. Until then it stays Schedule I at any amount. MGM-15 and MGM-16 stay Schedule I unchanged (FR 2026-20942).

Verbatim law on file for Massachusetts

1 instrument on file for this compound's framework in Massachusetts; 1 of 1 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

Mass. Gen. Laws ch. 94C, Sec. 1 (Controlled Substances Act; Definitions) · Definitions -- 'Controlled substance analogue' (and related 'Controlled substance', 'Tetrahydrocannabinol', and 'Marihuana' definitions)OFFICIAL
Instrument
Definitions -- 'Controlled substance analogue' (and related 'Controlled substance', 'Tetrahydrocannabinol', and 'Marihuana' definitions)
Source
https://malegislature.gov/Laws/GeneralLaws/PartI/TitleXV/Chapter94C/Section1
Retrieved
2026-07-02
Fingerprint
9a0f4c5c022d2a01
Section 1. As used in this chapter, the following words shall, unless the context clearly requires otherwise, have the following meanings:

"Controlled substance", a drug, substance, controlled substance analogue or immediate precursor in any schedule or class referred to in this chapter.

"Controlled substance analogue", (i) a drug or substance with a chemical structure substantially similar to the chemical structure of a controlled substance in Class A, B, C, D or E, listed in section 31 and which has a stimulant, depressant or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant or hallucinogenic effect on the central nervous system of a controlled substance in Class A, B, C, D or E, listed in said section 31; or (ii) a drug or substance with a chemical structure substantially similar to the chemical structure of a controlled substance in Class A, B, C, D or E, listed in said section 31 and with respect to a particular person, which such person represents or intends to have a stimulant, depressant or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant or hallucinogenic effect on the central nervous system of a controlled substance in Class A, B, C, D or E, listed in said section 31; provided, however, that "controlled substance analogue" shall not include: (1) a controlled substance; (2) any substance for which there is an approved new drug application; (3) with respect to a particular person, any substance for which there is an exception in effect for investigational use for that person, under section 8, to the extent conduct with respect to the substance is pursuant to such exemption; or (4) any substance not intended for human consumption before such an exemption takes effect with respect to that substance; provided, however, that for the purposes of this chapter, a "controlled substance analogue" shall be treated as the Class A, B, C, D or E substance of which it is a controlled substance analogue.

"Marihuana", all parts of the plant Cannabis sativa L., whether growing or not; the seeds thereof; and resin extracted from any part of the plant; and every compound, manufacture, salt, derivative, mixture, or preparation of the plant, its seeds or resin. It does not include the mature stalks of the plant, industrial hemp as defined in section 116 of chapter 128, fiber produced from the stalks, oil, or cake made from the seeds of the plant, any other compound, manufacture, salt, derivative, mixture, or preparation of the mature stalks, except the resin extracted therefrom, fiber, oil, or cake or the sterilized seed of the plant which is incapable of germination.

"Tetrahydrocannabinol", tetrahydrocannabinol or preparations containing tetrahydrocannabinol excluding marihuana except when it has been established that the concentration of delta-9 tetrahydrocannabinol in said marihuana exceeds two and one-half per cent.

Related

Mitragynine Pseudoindoxyl in neighboring states

Mitragynine Pseudoindoxyl in other states

Same framework in Massachusetts

Other compounds in Massachusetts

Cite this page

Compound Analytics. "Is Mitragynine Pseudoindoxyl Legal in Massachusetts? (2026)." Compound Laws, https://compoundlaws.com/compounds/pseudoindoxyl/massachusetts/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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