Massachusetts Mitragynine Pseudoindoxyl Ban (2026): In Force

Ban in force

As of November 4, 2026, Mitragynine Pseudoindoxyl is banned from retail sale in Massachusetts, effective August 28, 2026. The ban comes from federal scheduling, which takes precedence over state law.

Verified November 4, 2026. Full determination, citations and verbatim law: Is Mitragynine Pseudoindoxyl legal in Massachusetts?

Latest update September 22, 2026: Status changed from legal to illegal. Change history

When does the Massachusetts Mitragynine Pseudoindoxyl ban take effect?

The Massachusetts Mitragynine Pseudoindoxyl ban is already in force (effective August 28, 2026); no further effective date is pending.

Hotearliest DEA action in 0 days (DEA-1570 / FR 2026-20943); notice of intent by the DEA (Drug Enforcement Administration), applies to every seller; emergency rule by the DEA (Drug Enforcement Administration), applies to every seller

Earliest Nov 13, 2026
DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice)
Federal · Enforcement date · DEA-1570 / FR 2026-20943
DEA may act on or after this date. An order takes effect on publication with no grace period.
active October 14, 2026
DEA re-notices intent to place 7-OH and mitragynine pseudoindoxyl above 1 mg/g (or 1 mg/mL) or below a 100:1 mitragynine ratio in Schedule I; withdraws July 2026 notice
Federal · Notice of intent · DEA-1570; FR Doc. 2026-20943 · DEA (Drug Enforcement Administration) · applies to every seller
Products exceeding 1 mg per gram (solids) or 1 mg per mL (liquids) of 7-OH alone or combined with pseudoindoxyl, or with a mitragynine-to-7-OH mass ratio under 100, would be Schedule I; the order cannot issue before 30 days after publication (on or after November 13, 2026) and would run two years.
active October 14, 2026
DEA notice of intent to issue a new temporary order keeping MGM-15 and MGM-16 in Schedule I without a threshold
Federal · Notice of intent · DEA-1644; FR Doc. 2026-20942 · DEA (Drug Enforcement Administration) · applies to every seller
DEA will issue a fresh two-year temporary order for MGM-15 and MGM-16 (no threshold) so they are separated from the thresholded pseudoindoxyl rule; the August 26, 2026 order stays in force until the new order publishes or expires August 26, 2028.
active August 26, 2026
DEA temporary scheduling order places mitragynine pseudoindoxyl, MGM-15 and MGM-16 in Schedule I for two years
Federal · Emergency rule · DEA-1644; 91 FR 54948; FR Doc. 2026-17429 · DEA (Drug Enforcement Administration) · applies to every seller
Mitragynine pseudoindoxyl, MGM-15 (dihydro-7-hydroxymitragynine) and MGM-16 (9-fluoro-dihydro-7-hydroxymitragynine), with isomers, esters, ethers and salts, became Schedule I effective August 26, 2026 through August 26, 2028; DOJ announced enforcement discretion for incidental trace pseudoindoxyl in botanical kratom.

Show 2 more pending items

active July 6, 2026
Notice of intent to temporarily schedule mitragynine pseudoindoxyl, MGM-15 and MGM-16
Federal · Notice of intent · FR 2026-13581 / 91 FR 40909 · DEA (U.S. Drug Enforcement Administration) · advisory, not binding
Order "will be published in the Federal Register on or after August 5, 2026" and takes effect on publication. This is the single highest-value watch item for pseudoindoxyl -- it would replace interpretive isomer capture in AL, AR, IN and WI with a NAMED federal basis. Speciociliatine is in NEITHER docket.
final August 26, 2026
DOJ announces emergency scheduling of three 7-OH-related compounds and an enforcement-discretion policy for trace pseudoindoxyl in botanical kratom
Federal · Guidance · DEA (U.S. Department of Justice / Drug Enforcement Administration) · applies to every seller
DOJ stated it will exercise enforcement discretion where only incidental trace mitragynine pseudoindoxyl is confirmed in a product otherwise consistent with botanical kratom; the policy does not apply to MGM-15, MGM-16 or concentrated or added pseudoindoxyl and creates no legal exemption.

How the status got here

2026-09-22Status changed from legal to illegal.

Nearby

Connecticut Mitragynine Pseudoindoxyl ban banned
New Hampshire Mitragynine Pseudoindoxyl ban banned
New York Mitragynine Pseudoindoxyl ban banned
Rhode Island Mitragynine Pseudoindoxyl ban banned
Vermont Mitragynine Pseudoindoxyl ban banned

Other bans tracked in Massachusetts

Massachusetts 5-MeO-DMT ban ban in force
Massachusetts 7-OH ban ban in force
Massachusetts Ayahuasca ban ban in force
Massachusetts DMT ban ban in force
Massachusetts HHC ban ban in force
Massachusetts Ibogaine ban ban in force
Massachusetts Ketamine ban ban in force
Massachusetts Kratom ban ban in force
Massachusetts MGM-15 ban ban in force
Massachusetts MGM-16 ban ban in force
Massachusetts Peyote and Mescaline ban ban in force
Massachusetts Poppers ban ban in force
Massachusetts Psilocybin Mushrooms ban ban in force
Massachusetts THC-O Acetate ban ban in force
Massachusetts CBD ban no ban, gray area
Massachusetts CBG / CBDA / CBGA ban no ban, gray area
Massachusetts Delta-10 THC ban no ban, gray area
Massachusetts Delta-8 THC ban no ban, restricted
Massachusetts Delta-9 THC ban no ban, gray area
Massachusetts EPN / Euphorinol ban no ban, restricted
Massachusetts HHC-P ban no ban, gray area
Massachusetts THCP ban no ban, restricted
Massachusetts THCV ban no ban, restricted

Every state where Mitragynine Pseudoindoxyl is banned · All compounds in Massachusetts · Is Mitragynine Pseudoindoxyl Legal? Every state

Cite this page

Compound Analytics. “Massachusetts Mitragynine Pseudoindoxyl Ban (2026): In Force.” Compound Laws, https://compoundlaws.com/bans/pseudoindoxyl/massachusetts/. Accessed November 13, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

About · Methodology · Glossary · Changes · RSS · Data licensing · llms.txt · Sitemap