Is Mitragynine Pseudoindoxyl Legal in Florida? (2026)

Federal

Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) (effective 2026-08-26). State-law reading underneath: Illegal.

Rule type

emergency

Tier

schedule i

Schedule

schedule 1

Limit

1000 ppm w/w (=1 mg/g solids / 1 mg/mL liquids) AND product must contain >=100x mitragynine by mass (ppm dry weight)

Effective

2026-06-22

Effectively prohibitive

Concentrate; emergency rule names 7-OH only but KCPA age-21 scope applies

Controlling language, verbatim

FL Emergency Rule 2ER26-1 expressly names "Mitragynine pseudoindoxyl" among the compounds added to Schedule I, s. 893.03(1)(a) F.S. Trigger: > 1 mg/g (solids) / 1 mg/mL (liquids), OR a product with < 100 parts mitragynine per 1 part 7-OH-family compound (incl. pseudoindoxyl) by mass.

Source of excerpt

Citations

1. FL AG Emergency Rule (6/22/2026) - names mitragynine pseudoindoxyl among Schedule I 7-OH related compounds (Florida Office of the Attorney General, 2026-06-22) PRIMARYOFFICIAL
2. FL Emergency Rule 2ER26-1 (flrules.org) - names Mitragynine pseudoindoxyl; Schedule I 893.03(1)(a) (Florida Dept. of State / FAC, 2026-06-24) PRIMARYOFFICIAL
3. DEA Notice of Intent (7/1/2026) - names mitragynine pseudoindoxyl (with MGM-15/MGM-16) for temporary Schedule I (U.S. Drug Enforcement Administration, 2026-07-01)OFFICIAL

Where Mitragynine Pseudoindoxyl stands across the country

Among Florida's 2 neighbors, Alabama and Georgia are illegal, the same posture as Florida.

Open the interactive map · Every compound in Florida

Federal posture

Federally scheduled or prohibited. Pseudoindoxyl -- federally Schedule I (DEA temporary order, drug code 9672, eff. 2026-08-26) Federal detail

Pending deadlines

• 2026-08-01 · Federal · DEA temporary Schedule I order for mitragynine pseudoindoxyl, MGM-15, MGM-16 - effective on Federal Register publication (DEA NOI 2026-07-01)
• 2026-08-05 · Federal · DEA temporary Schedule I - mitragynine pseudoindoxyl, MGM-15, MGM-16 (DEA-1644 / FR 2026-17429)
  Second DEA Notice of Intent filed with the Federal Register on 7/1/2026 (companion to the 7-OH NOI, DEA-1570), placing three 7-OH-RELATED substances — mitragynine pseudoindoxyl (MP), MGM-15, and MGM-16 — into Schedule I under 21 U.S.C. 811(h). HHS confirmed these have no accepted medical use and a high potential for abuse. Same procedural clock as the 7-OH NOI: 30-day notice period, temporary order cannot issue before ~2026-08-05, effective on Federal Register publication of the order, 2-year duration (+1 yr possible). Unlike the 7-OH NOI there is NO concentration threshold here — these named substances are controlled outright. Confirm the exact companion docket number when the Federal Register posts on 7/6/2026.
• 2026-11-13 · Federal · DEA to replace pseudoindoxyl Schedule I order with a threshold order (re-notice) (DEA-1570 / FR 2026-20943)
  On or after Nov 13, 2026 DEA intends to withdraw the Aug 26 order (FR 2026-17429) and place pseudoindoxyl in Schedule I only above a threshold: more than 1 mg/g or 1 mg/mL alone or combined with 7-OH, or mitragynine under 100 times the pseudoindoxyl or combined amount. Until then it stays Schedule I at any amount. MGM-15 and MGM-16 stay Schedule I unchanged (FR 2026-20942).

Verbatim law on file for Florida

1 instrument on file for this compound's framework in Florida; 3 of 3 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

DEPARTMENT OF LEGAL AFFAIRS - Emergency Rule 2ER26-1. Rulemaking Authority s. 893.035 F.S.; Law Implemented s. 893.03, s. 893.035 F.S. History-New 7-1-26. Published Florida Administrative Register 6/24/2026, Vol. 52/122. Adopted on Attorney General James Uthmeier's written findings of imminent hazard (filed with Secretary of State).

RULE TITLE (compounds added, with chemical designations): Addition of 7-Hydroxymitragynine (methyl (E)-2-[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine (9-O-Demethylmitragynine, "8-OH"); 10-Hydroxycorynantheidine ("10-OH"); Mitragynine pseudoindoxyl (Methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine,-7'-yl]-3-methoxyprop-2-enoate); 7-Acetoxymitragynine; Dihydro-7-hydroxymitragynine ("MGM-15"); and 9-Fluoro-7-hydroxymitragynine ("MGM-16") TO SCHEDULE I, SUBSECTION 893.03(1)(a), F.S.

SUMMARY (verbatim): "The proposed emergency rule adds 7-hydroxymitragynine (\"7-OH\"), mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-hydroxymitragynine (\"8-OH\"), 10-hydroxymitragynine (\"10-OH\") dihydro-7-hydroxymitragynine (\"MGM-15\") and 9-fluoro-7-hydroxymitragynine (\"MGM-16\") at a level above (a) 1 milligram per gram (mg/g) for solid or powdered products, including encapsulated materials; or (b) 1 milligram per milliliter (mg/mL) for liquid products, including beverages, extracts, and tinctures; and 7-Hydroxymitragynine, Mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-Hydroxymitragynine, 10-Hydroxymitragynine, MGM-15, and MGM-16 (or any combination thereof) with less than 100 parts mitragynine for every one part of 7-OH (including Mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-Hydroxymitragynine, 10-Hydroxymitragynine, MGM-15, and MGM-16) by mass to Schedule I, subsection 893.03(l)(a), F.S."

FINDINGS (verbatim): "In written findings published on the date this emergency rule was filed with the Secretary of State's Office, Attorney General James Uthmeier has found that there is a need to schedule the above-mentioned substance in Schedule I, subsection 893.03(1)(a), F.S., on a temporary basis in order to curtail its abuse by Florida's children, young adults, and others. These circumstances present an imminent hazard to the public safety... The Legislature authorized the agency to adopt emergency rules to temporarily schedule substances in Schedule I, of section 893.03, F.S., pursuant to section 893.035(7), F.S."

Related

Mitragynine Pseudoindoxyl in neighboring states

• Mitragynine Pseudoindoxyl in Alabama Illegal
• Mitragynine Pseudoindoxyl in Georgia Illegal

Mitragynine Pseudoindoxyl in other states

Same framework in Florida

• 7-OH (7-Hydroxymitragynine) in Florida Illegal
• Kratom (Whole Leaf / Mitragynine) in Florida Restricted
• Speciociliatine in Florida Restricted

Other compounds in Florida

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