In Florida, Compound Laws tracks 19 compounds: 2 legal to sell at retail, 6 restricted, 1 in a gray area, 4 illegal, 1 not yet verified, and 5 whose status varies by product form. Verified through October 22, 2026.
0bb460448ed99295DEPARTMENT OF LEGAL AFFAIRS - Emergency Rule 2ER26-1. Rulemaking Authority s. 893.035 F.S.; Law Implemented s. 893.03, s. 893.035 F.S. History-New 7-1-26. Published Florida Administrative Register 6/24/2026, Vol. 52/122. Adopted on Attorney General James Uthmeier's written findings of imminent hazard (filed with Secretary of State).
RULE TITLE (compounds added, with chemical designations): Addition of 7-Hydroxymitragynine (methyl (E)-2-[(2S,3S,7aS,12bS)-3-ethyl-7a-hydroxy-8-methoxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate); 9-Hydroxycorynantheidine (9-O-Demethylmitragynine, "8-OH"); 10-Hydroxycorynantheidine ("10-OH"); Mitragynine pseudoindoxyl (Methyl (E)-2-[(2S,6'S,7'S,8'aS)-6'-ethyl-4-methoxy-3-oxospiro[1H-indole-2,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine,-7'-yl]-3-methoxyprop-2-enoate); 7-Acetoxymitragynine; Dihydro-7-hydroxymitragynine ("MGM-15"); and 9-Fluoro-7-hydroxymitragynine ("MGM-16") TO SCHEDULE I, SUBSECTION 893.03(1)(a), F.S.
SUMMARY (verbatim): "The proposed emergency rule adds 7-hydroxymitragynine (\"7-OH\"), mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-hydroxymitragynine (\"8-OH\"), 10-hydroxymitragynine (\"10-OH\") dihydro-7-hydroxymitragynine (\"MGM-15\") and 9-fluoro-7-hydroxymitragynine (\"MGM-16\") at a level above (a) 1 milligram per gram (mg/g) for solid or powdered products, including encapsulated materials; or (b) 1 milligram per milliliter (mg/mL) for liquid products, including beverages, extracts, and tinctures; and 7-Hydroxymitragynine, Mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-Hydroxymitragynine, 10-Hydroxymitragynine, MGM-15, and MGM-16 (or any combination thereof) with less than 100 parts mitragynine for every one part of 7-OH (including Mitragynine pseudoindoxyl, 7-acetoxymitragynine, 8-Hydroxymitragynine, 10-Hydroxymitragynine, MGM-15, and MGM-16) by mass to Schedule I, subsection 893.03(l)(a), F.S."
FINDINGS (verbatim): "In written findings published on the date this emergency rule was filed with the Secretary of State's Office, Attorney General James Uthmeier has found that there is a need to schedule the above-mentioned substance in Schedule I, subsection 893.03(1)(a), F.S., on a temporary basis in order to curtail its abuse by Florida's children, young adults, and others. These circumstances present an imminent hazard to the public safety... The Legislature authorized the agency to adopt emergency rules to temporarily schedule substances in Schedule I, of section 893.03, F.S., pursuant to section 893.035(7), F.S."94b008015bc58e97**Named entry** — "x. 4-Hydroxy-MET (4-Hydroxy-N-methyl-N-ethyltryptamine)." — Fla. Stat. § 893.03(1)(c)194., https://www.flsenate.gov/Laws/Statutes/2025/893.03 (official Florida Senate, 2025 Florida Statutes) **Class catch-all** — "194. Substituted Tryptamines.—Unless specifically excepted or unless listed in another schedule, or contained within a pharmaceutical product approved by the United States Food and Drug Administration, any material, compound, mixture, or preparation containing a 2-(1H-indol-3-yl)ethanamine, for example tryptamine, structure with or without mono- or di-substitution of the amine nitrogen with alkyl or alkenyl groups, or by inclusion of the amino nitrogen atom in a cyclic structure, whether or not substituted at the alpha position with an alkyl group, whether or not substituted on the indole ring to any extent with any alkyl, alkoxy, halo, hydroxyl, or acetoxy groups, including, but not limited to: …" — Fla. Stat. § 893.03(1)(c)194., same URL
8d0bf52687353cb2581.217(3)(e) ["Hemp" means] "the plant Cannabis sativa L. and any part of that plant, including the seeds thereof" [and] "all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers thereof" [with a] "total delta-9-tetrahydrocannabinol concentration that does not exceed 0.3 percent on a dry-weight basis." (3)(f) ["Hemp extract" means a substance] "intended for ingestion, containing more than trace amounts of a cannabinoid, or for inhalation" [...]. (7)(b) [Hemp extract] "may only be sold to a business in this state if that business is properly permitted as required by this section." (7)(d) [Products containing hemp extract intended for ingestion or inhalation] "may not be sold in this state to a person who is under 21 years of age." (12)(a) [testing] "post-decarboxylation or other similarly reliable methods." [Bracketed spans summarized.]
283e6354684326ae500.03 Definitions; construction; applicability.- (1) For the purpose of this chapter, the term: (n) "Food" includes: 1. Articles used for food or drink for human consumption; 2. Chewing gum; 3. Articles used for components of any such article; 4. Articles for which health claims are made, which claims are approved by the Secretary of the United States Department of Health and Human Services and which claims are made in accordance with s. 343(r) of the federal act, and which are not considered drugs solely because their labels or labeling contain health claims; 5. Dietary supplements as defined in 21 U.S.C. s. 321(ff)(1) and (2); and 6. Hemp extract as defined in s. 581.217. The term includes any raw, cooked, or processed edible substance; ice; any beverage; or any ingredient used, intended for use, or sold for human consumption. (4) For the purposes of this chapter, hemp extract is considered a food that requires time and temperature control for the safety and integrity of the product.
4b167cd4056ad38c581.217 State hemp program.- (1) CREATION AND PURPOSE.-The state hemp program is created within the department to regulate the cultivation of hemp in the state. This section constitutes the state plan for the regulation of the cultivation of hemp for purposes of 7 U.S.C. s. 1639p. (2) LEGISLATIVE FINDINGS.-The Legislature finds that: (a) Hemp is an agricultural commodity. (b) Hemp-derived cannabinoids, including, but not limited to, cannabidiol, are not controlled substances or adulterants if they are in compliance with this section. (3) DEFINITIONS.-As used in this section, the term: (a) "Attractive to children" means manufactured in the shape of humans, cartoons, or animals; manufactured in a form that bears any reasonable resemblance to an existing candy product that is familiar to the public as a widely distributed, branded food product such that a product could be mistaken for the branded product, especially by children; or containing any color additives. (b) "Certifying agency" has the same meaning as in s. 578.011(8). (c) "Contaminants unsafe for human consumption" includes, but is not limited to, any microbe, fungus, yeast, mildew, herbicide, pesticide, fungicide, residual solvent, metal, or other contaminant found in any amount that exceeds any of the accepted limitations as determined by rules adopted by the Department of Health in accordance with s. 381.986, or other limitation pursuant to the laws of this state, whichever amount is less. (d) "Cultivate" means planting, watering, growing, or harvesting hemp. (e) "Hemp" means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof, and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers thereof, whether growing or not, that has a total delta-9-tetrahydrocannabinol concentration that does not exceed 0.3 percent on a dry-weight basis, with the exception of hemp extract, which may not exceed 0.3 percent total delta-9-tetrahydrocannabinol on a wet-weight basis. (f) "Hemp extract" means a substance or compound intended for ingestion, containing more than trace amounts of a cannabinoid, or for inhalation which is derived from or contains hemp and which does not contain controlled substances. The term does not include synthetic cannabidiol or seeds or seed-derived ingredients that are generally recognized as safe by the United States Food and Drug Administration. (g) "Independent testing laboratory" means a laboratory that: 1. Does not have a direct or indirect interest in the entity whose product is being tested; 2. Does not have a direct or indirect interest in a facility that cultivates, processes, distributes, dispenses, or sells hemp or hemp extract in the state or in another jurisdiction or cultivates, processes, distributes, dispenses, or sells marijuana, as defined in s. 381.986; and 3. Is accredited by a third-party accrediting body as a competent testing laboratory pursuant to ISO/IEC 17025 of the International Organization for Standardization.
6091966a00665b1a(e) "Hemp" means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof, and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers thereof, whether growing or not, that has a total delta-9-tetrahydrocannabinol concentration that does not exceed 0.3 percent on a dry-weight basis, with the exception of hemp extract, which may not exceed 0.3 percent total delta-9-tetrahydrocannabinol on a wet-weight basis. (f) "Hemp extract" means a substance or compound intended for ingestion, containing more than trace amounts of a cannabinoid, or for inhalation which is derived from or contains hemp and which does not contain controlled substances. The term does not include synthetic cannabidiol or seeds or seed-derived ingredients that are generally recognized as safe by the United States Food and Drug Administration. (7) DISTRIBUTION AND RETAIL SALE OF HEMP EXTRACT.-- (a) Hemp extract may only be distributed and sold in the state if the product: 1. Has a certificate of analysis prepared by an independent testing laboratory that states: a. The hemp extract is the product of a batch tested by the independent testing laboratory; b. The batch contained a total delta-9-tetrahydrocannabinol concentration that did not exceed 0.3 percent pursuant to the testing of a random sample of the batch; c. The batch does not contain contaminants unsafe for human consumption; and d. The batch was processed in a facility that holds a current and valid permit issued by a human health or food safety regulatory entity with authority over the facility, and that facility meets the human health or food safety sanitization requirements of the regulatory entity. Such compliance must be documented by a report from the regulatory entity confirming that the facility meets such requirements. 2. Is distributed or sold in a container that includes: a. A scannable barcode or quick response code linked to the certificate of analysis of the hemp extract batch by an independent testing laboratory; b. The batch number; c. The Internet address of a website where batch information may be obtained; d. The expiration date; and e. The number of milligrams of each marketed cannabinoid per serving. (d) Products that are intended for human ingestion or inhalation and that contain hemp extract, including, but not limited to, snuff, chewing gum, and other smokeless products, may not be sold in this state to a person who is under 21 years of age.
d5864334ac8438a4(7) DISTRIBUTION AND RETAIL SALE OF HEMP EXTRACT.- (a) Hemp extract may only be distributed and sold in the state if the product: 1. Has a certificate of analysis prepared by an independent testing laboratory that states: a. The hemp extract is the product of a batch tested by the independent testing laboratory; b. The batch contained a total delta-9-tetrahydrocannabinol concentration that did not exceed 0.3 percent pursuant to the testing of a random sample of the batch; c. The batch does not contain contaminants unsafe for human consumption; and d. The batch was processed in a facility that holds a current and valid permit issued by a human health or food safety regulatory entity with authority over the facility, and that facility meets the human health or food safety sanitization requirements of the regulatory entity. Such compliance must be documented by a report from the regulatory entity confirming that the facility meets such requirements. 2. Is distributed or sold in a container that includes: a. A scannable barcode or quick response code linked to the certificate of analysis of the hemp extract batch by an independent testing laboratory; b. The batch number; c. The Internet address of a website where batch information may be obtained; d. The expiration date; and e. The number of milligrams of each marketed cannabinoid per serving. 3. Is distributed or sold in a container that: a. Is suitable to contain products for human consumption; b. Is composed of materials designed to minimize exposure to light; c. Mitigates exposure to high temperatures; d. Is not attractive to children; and e. Is compliant with the United States Poison Prevention Packaging Act of 1970, 15 U.S.C. ss. 1471 et seq., without regard to provided exemptions. (b) Hemp extract may only be sold to a business in this state if that business is properly permitted as required by this section. (c) Hemp extract distributed or sold in this state is subject to the applicable requirements of chapter 500, chapter 502, or chapter 580. (d) Products that are intended for human ingestion or inhalation and that contain hemp extract, including, but not limited to, snuff, chewing gum, and other smokeless products, may not be sold in this state to a person who is under 21 years of age. A person who violates this paragraph commits a misdemeanor of the second degree, punishable as provided in s. 775.082 or s. 775.083. A person who commits a second or subsequent violation of this paragraph within 1 year after the initial violation commits a misdemeanor of the first degree, punishable as provided in s. 775.082 or s. 775.083. (e) Hemp extract distributed or sold in violation of this subsection is subject to s. 500.172 and penalties as provided in s. 500.121. Hemp extract products found to be mislabeled or attractive to children are subject to an immediate stop-sale order.
8620c99cca2dd898192. Substituted Phenethylamines.-Unless specifically excepted or unless listed in another schedule, or contained within a pharmaceutical product approved by the United States Food and Drug Administration, any material, compound, mixture, or preparation, including its salts, isomers, esters, or ethers, and salts of isomers, esters, or ethers, whenever the existence of such salts is possible within any of the following specific chemical designations, any compound containing a phenethylamine structure, without a beta-keto group, and without a benzyl group attached to the amine group, whether or not the compound is further modified with or without substitution on the phenyl ring to any extent with alkyl, alkylthio, nitro, alkoxy, thio, halide, fused alkylenedioxy, fused furan, fused benzofuran, fused dihydrofuran, or fused tetrahydropyran substituents, whether or not further substituted on a ring to any extent, with or without substitution at the alpha or beta position by any alkyl substituent, with or without substitution at the nitrogen atom, and with or without inclusion of the 2-amino nitrogen atom in a cyclic structure, including, but not limited to: a. 2C-B (4-Bromo-2,5-dimethoxyphenethylamine). b. 2C-E (4-Ethyl-2,5-dimethoxyphenethylamine). c. 2C-T-4 (4-Isopropylthio-2,5-dimethoxyphenethylamine). d. 2C-C (4-Chloro-2,5-dimethoxyphenethylamine). e. 2C-T (4-Methylthio-2,5-dimethoxyphenethylamine). f. 2C-T-2 (4-Ethylthio-2,5-dimethoxyphenethylamine). g. 2C-T-7 (4-(n)-Propylthio-2,5-dimethoxyphenethylamine). h. 2C-I (4-Iodo-2,5-dimethoxyphenethylamine). i. 2C-D (4-Methyl-2,5-dimethoxyphenethylamine). j. 2C-H (2,5-Dimethoxyphenethylamine). k. 2C-N (4-Nitro-2,5-dimethoxyphenethylamine). l. 2C-P (4-(n)-Propyl-2,5-dimethoxyphenethylamine). m. MDMA (3,4-Methylenedioxymethamphetamine). n. MBDB (Methylbenzodioxolylbutanamine) or (3,4-Methylenedioxy-N-methylbutanamine). o. MDA (3,4-Methylenedioxyamphetamine). p. 2,5-Dimethoxyamphetamine. q. Fluoroamphetamine. r. Fluoromethamphetamine. s. MDEA (3,4-Methylenedioxy-N-ethylamphetamine). t. DOB (4-Bromo-2,5-dimethoxyamphetamine). u. DOC (4-Chloro-2,5-dimethoxyamphetamine). v. DOET (4-Ethyl-2,5-dimethoxyamphetamine). w. DOI (4-Iodo-2,5-dimethoxyamphetamine). x. DOM (4-Methyl-2,5-dimethoxyamphetamine). y. PMA (4-Methoxyamphetamine). z. N-Ethylamphetamine. aa. 3,4-Methylenedioxy-N-hydroxyamphetamine. bb. 5-Methoxy-3,4-methylenedioxyamphetamine. cc. PMMA (4-Methoxymethamphetamine). dd. N,N-Dimethylamphetamine. ee. 3,4,5-Trimethoxyamphetamine. ff. 4-APB (4-(2-Aminopropyl)benzofuran). gg. 5-APB (5-(2-Aminopropyl)benzofuran). hh. 6-APB (6-(2-Aminopropyl)benzofuran). ii. 7-APB (7-(2-Aminopropyl)benzofuran). jj. 4-APDB (4-(2-Aminopropyl)-2,3-dihydrobenzofuran). kk. 5-APDB (5-(2-Aminopropyl)-2,3-dihydrobenzofuran). ll. 6-APDB (6-(2-Aminopropyl)-2,3-dihydrobenzofuran). mm. 7-APDB (7-(2-Aminopropyl)-2,3-dihydrobenzofuran). nn. 4-MAPB (4-(2-Methylaminopropyl)benzofuran). oo. 5-MAPB (5-(2-Methylaminopropyl)benzofuran). pp. 6-MAPB (6-(2-Methylaminopropyl)benzofuran). qq. 7-MAPB (7-(2-Methylaminopropyl)benzofuran). rr. 5-EAPB (5-(2-Ethylaminopropyl)benzofuran). ss. 5-MAPDB (5-(2-Methylaminopropyl)-2,3-dihydrobenzofuran), which does not include phenethylamine, mescaline as described in subparagraph 20., substituted cathinones as described in subparagraph 191., N-Benzyl phenethylamine compounds as described in subparagraph 193., or methamphetamine as described in subparagraph (2)(c)5.
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