As of October 8, 2026, Amanita muscaria / Muscimol is legal to sell at retail in South Carolina. Not named on South Carolina schedules or in any state law; edibles reachable only via general food-adulteration law. Controlling source: S.C. Code Title 44, Ch. 53.
Verified October 8, 2026 · confidence: confirmedNothing in S.C. Code Sec. 44-53-190 (Schedule I) names Amanita muscaria, muscimol, or ibotenic acid (official text fetched 2026-10-07; psilocybin is listed, these are not). No South Carolina statute or rule names these compounds, so the only reach is general food adulteration law read with FDA's Dec. 18, 2024 determination that A. muscaria and its constituents are unapproved food additives, which does not reach inhaled products such as vapes. Analogue-act reach is remote because muscimol and ibotenic acid are not structurally similar to any Schedule I or II hallucinogen.
Among South Carolina's 2 neighbors, Georgia and North Carolina are legal, the same posture as South Carolina.
Open the interactive map · Every compound in South Carolina
Federal gray area. Not federally scheduled; FDA says A. muscaria, muscimol, ibotenic acid are unapproved food additives, unsafe in food. Federal detail
2 instruments on file for this compound's framework in South Carolina; 3 of 3 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
2ac96b8e28ca164c**§ 44-53-190(D) (hallucinogen chapeau)** — "(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:" — S.C. Code § 44-53-190(D), https://www.scstatehouse.gov/code/t44c053.php (OFFICIAL — SC Legislature). The enumerated tryptamines are Bufotenine, DET, DMT, Psilocybin, Psilocyn only; 4-HO-MET is not present, and no tryptamine structural class exists in § 44-53-190. **§ 44-53-110(7) (controlled substance analogue)** — "'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III." — S.C. Code § 44-53-110(7), https://law.justia.com/codes/south-carolina/2022/title-44/chapter-53/section-44-53-110/ (MIRROR: Justia; canonical version identical).
fcee94a41f3ee741S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;
Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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