Is Amanita muscaria / Muscimol Legal in South Carolina? (2026)

Legal

As of October 8, 2026, Amanita muscaria / Muscimol is legal to sell at retail in South Carolina. Not named on South Carolina schedules or in any state law; edibles reachable only via general food-adulteration law. Controlling source: S.C. Code Title 44, Ch. 53.

Verified October 8, 2026 · confidence: confirmed
Rule type
permanent
Tier
unscheduled

What the record says

Nothing in S.C. Code Sec. 44-53-190 (Schedule I) names Amanita muscaria, muscimol, or ibotenic acid (official text fetched 2026-10-07; psilocybin is listed, these are not). No South Carolina statute or rule names these compounds, so the only reach is general food adulteration law read with FDA's Dec. 18, 2024 determination that A. muscaria and its constituents are unapproved food additives, which does not reach inhaled products such as vapes. Analogue-act reach is remote because muscimol and ibotenic acid are not structurally similar to any Schedule I or II hallucinogen.

Citations

  1. S.C. Code Title 44, Ch. 53 (South Carolina Legislature, 2026-10-07) PRIMARYOFFICIAL
  2. FDA Alerts Industry and Consumers about the Use of Amanita Muscaria or its Constituents in Food (Constituent Update, Dec. 18, 2024) (U.S. Food and Drug Administration, 2026-10-07) PRIMARYOFFICIAL
  3. Amanita muscaria (Fly Agaric) Fact Sheet (Mar. 2026) (Legislative Analysis and Public Policy Association (LAPPA), 2026-10-07)OFFICIAL

Where Amanita muscaria / Muscimol stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among South Carolina's 2 neighbors, Georgia and North Carolina are legal, the same posture as South Carolina.

Open the interactive map · Every compound in South Carolina

Federal posture

Federal gray area. Not federally scheduled; FDA says A. muscaria, muscimol, ibotenic acid are unapproved food additives, unsafe in food. Federal detail

Verbatim law on file for South Carolina

2 instruments on file for this compound's framework in South Carolina; 3 of 3 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

S.C. Code § 44-53-190(D) (Schedule I hallucinogens — enumerated, 4-HO-MET absent); S.C. Code § 44-53-110(7) (controlled substance analogue)OFFICIAL
Instrument
statute
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-06-19
Fingerprint
2ac96b8e28ca164c
**§ 44-53-190(D) (hallucinogen chapeau)** — "(D) Any material, compound, mixture, or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers, and salts of isomers, unless specifically excepted, whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:"
— S.C. Code § 44-53-190(D), https://www.scstatehouse.gov/code/t44c053.php (OFFICIAL — SC Legislature). The enumerated tryptamines are Bufotenine, DET, DMT, Psilocybin, Psilocyn only; 4-HO-MET is not present, and no tryptamine structural class exists in § 44-53-190.
**§ 44-53-110(7) (controlled substance analogue)** — "'Controlled substance analogue' means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III."
— S.C. Code § 44-53-110(7), https://law.justia.com/codes/south-carolina/2022/title-44/chapter-53/section-44-53-110/ (MIRROR: Justia; canonical version identical).
S.C. Code Ann. Sec. 44-53-110(7) & Sec. 44-53-370(a)(1) · Controlled substance analogue definition and prohibited acts (analogue offense)OFFICIAL
Instrument
Controlled substance analogue definition and prohibited acts (analogue offense)
Source
https://www.scstatehouse.gov/code/t44c053.php
Retrieved
2026-07-20
Fingerprint
fcee94a41f3ee741
S.C. Code Ann. Section 44-53-110(7): (7) "Controlled substance analogue" means a substance that is intended for human consumption and that either has a chemical structure substantially similar to that of a controlled substance in Schedules I, II, or III or has a stimulant, depressant, analgesic, or hallucinogenic effect on the central nervous system that is substantially similar to that of a controlled substance in Schedules I, II, or III. Controlled substance analogue does not include a controlled substance; any substance generally recognized as safe and effective within the meaning of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 301 et seq.; any substance for which there is an approved new drug application; or, with respect to a particular person, any substance if an exemption is in effect for investigational use for that person under Section 505 of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. 355. S.C. Code Ann. Section 44-53-370(a): Except as authorized by this article it shall be unlawful for any person: (1) to manufacture, distribute, dispense, deliver, purchase, aid, abet, attempt, or conspire to manufacture, distribute, dispense, deliver, or purchase, or possess with the intent to manufacture, distribute, dispense, deliver, or purchase a controlled substance or a controlled substance analogue;

Related

Amanita muscaria / Muscimol in neighboring states

Amanita muscaria / Muscimol in other states

Same framework in South Carolina

Other compounds in South Carolina

Cite this page

Compound Analytics. "Is Amanita muscaria / Muscimol Legal in South Carolina? (2026)." Compound Laws, https://compoundlaws.com/compounds/amanita-muscimol/south-carolina/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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