Is DMT Legal in Missouri? (2026)

Instrument

Executive Order 24-10 -- directing DHSS to designate foods containing unregulated psychoactive cannabis products as coming from an unapproved food source / containing an unapproved food additive, and to embargo and condemn such foods; directing Division of Alcohol and Tobacco Control to prohibit sale on liquor-licensed premises

Source

https://www.sos.mo.gov/library/reference/orders/2024/eo10

Retrieved

2026-07-02

Fingerprint

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EXECUTIVE ORDER 24-10

WHEREAS, there are currently no safety standards, packaging requirements, or other regulations related to the safety of consuming unregulated psychoactive cannabis products in Missouri; and

WHEREAS, unregulated psychoactive cannabis products include delta-8 tetrahydrocannabinol (THC), delta-10 THC, hexahydrocannabinol (HHC), tetrahydrocannabinol (THC-O), tetrahydrocannabiphoral (THCP), tetrahydrocannabivarin (THCV), and other similar compounds; and

WHEREAS, numerous Missourians have been negatively impacted by the consumption of foods with unregulated psychoactive cannabis products added to them; and

WHEREAS, Missouri children, and children across the nation, have been hospitalized due to consuming unregulated psychoactive cannabis products; and

WHEREAS, additional actions must be taken to protect consumers, including children, from the sale of foods that include unregulated psychoactive cannabis products; and

WHEREAS, the Missouri Department of Health and Senior Services (DHSS) is tasked with ensuring the protection of the public when it comes to food under Chapter 196, RSMo; and

WHEREAS, the DHSS is tasked with promulgating regulations that conform, insofar as practicable, with those promulgated under federal acts under Section 196.045, RSMo; and

WHEREAS, state law currently prohibits the sale of foods that are adulterated or misbranded under Section 196.015, RSMo; and

WHEREAS, the DHSS has promulgated rules and a Food Code under Section 196.045, RSMo, which align with the United States Food and Drug Administration (FDA); and

WHEREAS, the FDA and the Missouri Food Code require that all food come from approved sources; and

WHEREAS, the FDA and the Missouri Food Code require that food that is not from an approved source shall be discarded; and

WHEREAS, the FDA and the Missouri Food Code require that food additives must be approved food additives or come from approved food sources; and

WHEREAS, there is no unregulated psychoactive cannabis product that has been approved by the FDA as a food additive; and

WHEREAS, the FDA has stated that food additives must receive premarket approval, and the failure to obtain premarket approval causes the food to be marked as adulterated by the FDA; and

WHEREAS, Section 311.660, RSMo, provides the Missouri Division of Alcohol and Tobacco Control within the Missouri Department of Public Safety with the statutory authority to enforce Missouri's alcohol and tobacco laws and regulations to ensure a safe environment for citizens of Missouri; and

WHEREAS, Missouri regulations currently prohibit the sale of controlled substances on liquor-licensed premises, but are silent on the sale of other unregulated psychoactive cannabis products.

NOW, THEREFORE, I, MICHAEL L. PARSON, GOVERNOR OF THE STATE OF MISSOURI, by virtue and authority vested in me by the Constitution and laws of the State of Missouri, do hereby order the DHSS, beginning on September 1, 2024, to designate foods containing unregulated psychoactive cannabis products as foods that come from an unapproved food source or as foods that contain an unapproved food additive that comes from an unapproved food source as set forth in the 2022 FDA Food Code and the 2013 Missouri Food Code, or revisions of said codes. Additionally, the DHSS is to find foods that contain unregulated psychoactive cannabis products are deleterious, poisonous, and adulterated under Sections 196.070, RSMo, and 196.085, RSMo, and to take the necessary steps in accordance with statute and regulation to embargo and condemn any food containing unregulated psychoactive cannabis products. These provisions do not apply to products under the control or purview of the Division of Cannabis Regulation under Article XIV of the Missouri Constitution as long as all psychoactive cannabinoids in those products are sourced from establishments licensed under Article XIV of the Missouri Constitution.

I further direct the DHSS to produce and distribute information regarding how the DHSS will regulate products consistent with this Executive Order.

I further direct the Missouri Division of Alcohol and Tobacco Control to amend its regulations such that unregulated psychoactive cannabis products are prohibited from being sold on the premises of a liquor-licensed facility.

IN WITNESS WHEREOF, I have hereunto set my hand and caused to be affixed the Great Seal of the State of Missouri, in the City of Jefferson, on this 1st day of August, 2024.

MICHAEL L. PARSON, GOVERNOR

ATTEST: JOHN R. ASHCROFT, SECRETARY OF STATE

Instrument

Substances, how placed in schedules; Schedule I hallucinogenic substances

Source

https://revisor.mo.gov/main/OneSection.aspx?section=195.017

Retrieved

2026-10-28

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(5)  Any material, compound, mixture or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers and salts of isomers, unless specifically excepted, whenever the existence of these salts, isomers, and salts of isomers is possible within the specific chemical designation:

  (a)  Alpha-ethyltryptamine;

  (b)  4-bromo-2,5-dimethoxyamphetamine;

  (c)  4-bromo-2,5-dimethoxyphenethylamine;

  (d)  2,5-dimethoxyamphetamine;

  (e)  2,5-dimethoxy-4-ethylamphetamine;

  (f)  2,5-dimethoxy-4-(n)-propylthiophenethylamine;

  (g)  2-(2,5-Dimethoxy-4-(n)-propylphenyl) ethanamine;

  (h)  2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine;

  (i)  2-(2,5-Dimethoxy-4-methylphenyl) ethanamine;

  (j)  2-(2,5-Dimethoxy-4-nitro-phenyl) ethanamine;

  (k)  2-(2,5-Dimethoxyphenyl) ethanamine;

  (l)  2-(4-Chloro-2,5-dimethoxyphenyl) ethanamine;

  (m)  2-(4-Ethylthio-2,5-dimethoxyphenyl) ethanamine;

  (n)  2-(4-Iodo-2,5-dimethoxyphenyl) ethanamine;

  (o)  2-(4-
Isopropylthio
)-2,5-dimethoxyphenyl) ethanamine;

  (p)  4-methoxyamphetamine;

  (q)  5-methoxy-3,4-methylenedioxyamphetamine;

  (r)  4-methyl-2, 5-dimethoxyamphetamine;

  (s)  3,4-methylenedioxyamphetamine;

  (t)  3,4-methylenedioxymethamphetamine;

  (u)  3,4-methylenedioxy-N-ethylamphetamine;

  (v)  N-hydroxy-3, 4-methylenedioxyamphetamine;

  (w)  3,4,5-trimethoxyamphetamine;

  (x)  5-MeO-DMT or 5-methoxy-N,N-dimethyltryptamine;

  (y)  Alpha-methyltryptamine;

  (z)  Bufotenine;

  (aa)  Diethyltryptamine;

  (bb)  Dimethyltryptamine;

  (cc)  5-methoxy-N,N-diisopropyltryptamine;

  (dd)  Ibogaine;

  (ee)  Lysergic acid diethylamide;

  (ff)  Marijuana or marihuana, except industrial hemp;

  (gg)  Mescaline;

  (hh)  Parahexyl;

  (ii)  Peyote, to include all parts of the plant presently classified botanically as Lophophora williamsii Lemaire, whether growing or not; the seeds thereof; any extract from any part of such plant; and every compound, manufacture, salt, derivative, mixture or preparation of the plant, its seed or extracts;

  (jj)  N-ethyl-3-piperidyl benzilate;

  (kk)  N-methyl-3-piperidyl benzilate;

  (ll)  Psilocybin;

  (mm)  Psilocyn;

  (nn)  Tetrahydrocannabinols naturally contained in a plant of the genus Cannabis (cannabis plant), except industrial hemp, as well as synthetic equivalents of the substances contained in the cannabis plant, or in the resinous extractives of such plant, or synthetic substances, derivatives and their isomers, or both, with similar chemical structure and pharmacological activity to those substances contained in the plant, such as the following:

  a.  1 cis or trans tetrahydrocannabinol and their optical isomers;

  b.  6 cis or trans tetrahydrocannabinol and their optical isomers;

  c.  3,4 cis or trans tetrahydrocannabinol and their optical isomers;

  d.  Any compounds of these structures, regardless of numerical designation of atomic positions covered;

  (oo)  Ethylamine analog of phencyclidine;

  (pp)  Pyrrolidine analog of phencyclidine;

  (qq)  Thiophene analog of phencyclidine;

  (rr)  1-
[
1-(2-thienyl)cyclohexyl
]
pyrrolidine;

  (ss)  Salvia divinorum;

  (tt)  Salvinorin A;

Instrument

Substances, how placed in schedules (Schedule I, hallucinogenic substances)

Source

https://revisor.mo.gov/main/OneSection.aspx?section=195.017

Retrieved

2026-11-06

Fingerprint

970cc73abbffa0c9

  (5)  Any material, compound, mixture or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers and salts of isomers, unless specifically excepted, whenever the existence of these salts, isomers, and salts of isomers is possible within the specific chemical designation:

  (a)  Alpha-ethyltryptamine;

  (b)  4-bromo-2,5-dimethoxyamphetamine;

  (c)  4-bromo-2,5-dimethoxyphenethylamine;

  (d)  2,5-dimethoxyamphetamine;

  (e)  2,5-dimethoxy-4-ethylamphetamine;

  (f)  2,5-dimethoxy-4-(n)-propylthiophenethylamine;

  (g)  2-(2,5-Dimethoxy-4-(n)-propylphenyl) ethanamine;

  (h)  2-(2,5-Dimethoxy-4-ethylphenyl) ethanamine;

  (i)  2-(2,5-Dimethoxy-4-methylphenyl) ethanamine;

  (j)  2-(2,5-Dimethoxy-4-nitro-phenyl) ethanamine;

  (k)  2-(2,5-Dimethoxyphenyl) ethanamine;

  (l)  2-(4-Chloro-2,5-dimethoxyphenyl) ethanamine;

  (m)  2-(4-Ethylthio-2,5-dimethoxyphenyl) ethanamine;

  (n)  2-(4-Iodo-2,5-dimethoxyphenyl) ethanamine;

  (o)  2-(4-
Isopropylthio
)-2,5-dimethoxyphenyl) ethanamine;

  (p)  4-methoxyamphetamine;

  (q)  5-methoxy-3,4-methylenedioxyamphetamine;

  (r)  4-methyl-2, 5-dimethoxyamphetamine;

  (s)  3,4-methylenedioxyamphetamine;

  (t)  3,4-methylenedioxymethamphetamine;

  (u)  3,4-methylenedioxy-N-ethylamphetamine;

  (v)  N-hydroxy-3, 4-methylenedioxyamphetamine;

  (w)  3,4,5-trimethoxyamphetamine;

  (x)  5-MeO-DMT or 5-methoxy-N,N-dimethyltryptamine;

  (y)  Alpha-methyltryptamine;

  (z)  Bufotenine;

  (aa)  Diethyltryptamine;

  (bb)  Dimethyltryptamine;

  (cc)  5-methoxy-N,N-diisopropyltryptamine;

  (dd)  Ibogaine;

  (ee)  Lysergic acid diethylamide;

  (ff)  Marijuana or marihuana, except industrial hemp;

  (gg)  Mescaline;

  (hh)  Parahexyl;

  (ii)  Peyote, to include all parts of the plant presently classified botanically as Lophophora williamsii Lemaire, whether growing or not; the seeds thereof; any extract from any part of such plant; and every compound, manufacture, salt, derivative, mixture or preparation of the plant, its seed or extracts;

  (jj)  N-ethyl-3-piperidyl benzilate;

  (kk)  N-methyl-3-piperidyl benzilate;

  (ll)  Psilocybin;

  (mm)  Psilocyn;

  (nn)  Tetrahydrocannabinols naturally contained in a plant of the genus Cannabis (cannabis plant), except industrial hemp, as well as synthetic equivalents of the substances contained in the cannabis plant, or in the resinous extractives of such plant, or synthetic substances, derivatives and their isomers, or both, with similar chemical structure and pharmacological activity to those substances contained in the plant, such as the following:

  a.  1 cis or trans tetrahydrocannabinol and their optical isomers;

  b.  6 cis or trans tetrahydrocannabinol and their optical isomers;

  c.  3,4 cis or trans tetrahydrocannabinol and their optical isomers;

  d.  Any compounds of these structures, regardless of numerical designation of atomic positions covered;

  (oo)  Ethylamine analog of phencyclidine;

  (pp)  Pyrrolidine analog of phencyclidine;

  (qq)  Thiophene analog of phencyclidine;

  (rr)  1-
[
1-(2-thienyl)cyclohexyl
]
pyrrolidine;

  (ss)  Salvia divinorum;

  (tt)  Salvinorin A;

  (uu)  Synthetic cannabinoids:

  a.  Any compound structurally derived from 3-(1-naphthoyl)indole or 1H-indol-3-yl-(1-naphthyl)methane by substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent, whether or not substituted in the naphthyl ring to any extent.  Including, but not limited to:

  (i)  AM2201, or 1-(5-fluoropentyl)-3-(1-naphthoyl)indole;

  (ii)  JWH-007, or 1-pentyl-2-methyl-3-(1-naphthoyl)indole;

  (iii)  JWH-015, or 1-propyl-2-methyl-3-(1-naphthoyl)indole;

  (iv)  JWH-018, or 1-pentyl-3-(1-naphthoyl)indole;

  (v)  JWH-019, or 1-hexyl-3-(1-naphthoyl)indole;

  (vi)  JWH-073, or 1-butyl-3-(1-naphthoyl)indole;

  (vii)  JWH-081, or 1-pentyl-3-(4-methoxy-1-naphthoyl)indole;

  (viii)  JWH-098, or 1-pentyl-2-methyl-3-(4-methoxy-1-naphthoyl)indole;

  (ix)  JWH-122, or 1-pentyl-3-(4-methyl-1-naphthoyl)indole;

  (x)  JWH-164, or 1-pentyl-3-(7-methoxy-1-naphthoyl)indole;

  (xi)  JWH-200, or 1-(2-(4-(morpholinyl)ethyl))-3-(1-naphthoyl)indole;

  (xii)  JWH-210, or 1-pentyl-3-(4-ethyl-1-naphthoyl)indole;

  (xiii)  JWH-398, or 1-pentyl-3-(4-chloro-1-naphthoyl)indole;

  b.  Any compound structurally derived from 3-(1-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the pyrrole ring to any extent, whether or not substituted in the naphthyl ring to any extent;

  c.  Any compound structurally derived from 1-(1-naphthylmethyl)indene by substitution at the 3-position of the indene ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indene ring to any extent, whether or not substituted in the naphthyl ring to any extent;

  d.  Any compound structurally derived from 3-phenylacetylindole by substitution at the nitrogen atom of the indole ring with alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent, whether or not substituted in the phenyl ring to any extent.  Including, but not limited to:

  (i)  JWH-201, or 1-pentyl-3-(4-methoxyphenylacetyl)indole;

  (ii)  JWH-203, or 1-pentyl-3-(2-chlorophenylacetyl)indole;

  (iii)  JWH-250, or 1-pentyl-3-(2-methoxyphenylacetyl)indole;

  (iv)  JWH-251, or 1-pentyl-3-(2-methylphenylacetyl)indole;

  (v)  RCS-8, or 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole;

  e.  Any compound structurally derived from 2-(3-hydroxycyclohexyl)phenol by substitution at the 5-position of the phenolic ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not substituted in the cyclohexyl ring to any extent.  Including, but not limited to CP 47, 497 and homologues, or 2-
[
(1R,3S)-3-hydroxycyclohexyl
]
-5-(2-methyloctan-2-yl)phenol, where side chain n=5, and homologues where side chain n-4,6, or 7;

  f.  Any compound containing a 3-(benzoyl)indole structure with substitution at the nitrogen atom of the indole ring by alkyl, haloalkyl, alkenyl, cycloalkylmethyl, cycloalkylethyl, 1-(N-methyl-2-piperidinyl)methyl or 2-(4-morpholinyl)ethyl group, whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent.  Including, but not limited to:

  (i)  AM-694, or 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole;

  (ii)  RCS-4, or 1-pentyl-3-(4-methoxybenzoyl)indole (SR-19 and RCS-4);

  g.  CP 50,556-1, or
[
(6S,6aR,9R,10aR)-9-hydroxy-6-methyl-3-
[
(2R)-5-phenylpentan-2-yl
]
 oxy-5,6,6a,7,8,9,10,10a-octahydrophenanthridin-1-yl
]
 acetate;

  h.  HU-210, or (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo
[
c
]
chromen-1-ol;

  i.  HU-211, or Dexanabinol,(6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo
[
c
]
chromen-1-ol;

  j.  Dimethylheptylpyran, or DMHP;