As of November 12, 2026, Ketamine is illegal to sell (federally scheduled; state law on file reads illegal) in Kentucky. Federally Schedule III; lawful possession and use is by prescription or DEA registration only. Controlling source: 902 KAR 55:015 Section 3 (Schedule III adopts 21 CFR 1308.13).
Verified November 12, 2026 (hash check) · confidence: confirmedIs Ketamine Legal? Every state and federal law
Kentucky Ketamine ban status: ban in force
902 KAR 55:015 Section 3(1) schedules at the state level every substance on federal Schedule III (21 CFR 1308.13), which lists "Ketamine, its salts, isomers, and salts of isomers" at 1308.13(c)(7); Kentucky’s own Schedule III designations (pentazocine and three barbiturates) do not change that. The federal isomer language covers esketamine. Lawful channels are prescription ketamine, esketamine nasal spray (Spravato) under its FDA REMS, and compounded ketamine on a prescription. No Kentucky rule naming ketamine clinics or ketamine telehealth was found. 2-FDCK is temporarily Schedule I federally and is therefore Schedule I in Kentucky through Section 1(1). Federally Schedule III (see the federal page).
each substance that is scheduled or designated as a Schedule III controlled substance under 21 C.F.R. 1308.13 shall be scheduled or designated at the state level as a Schedule III controlled substance.
Among Kentucky’s 7 neighbors, Illinois, Indiana, Missouri, Ohio, Tennessee, Virginia and West Virginia are illegal, the same posture as Kentucky.
Open the interactive map · Every compound in Kentucky · Where Ketamine is banned · Embed this map
Federally scheduled or prohibited. Federally Schedule III; lawful possession and use is by prescription or DEA registration only Federal detail
8 instruments on file for this compound’s framework in Kentucky; 3 of 3 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
0b9c324d7f9d4db3Section 1. Schedule I Controlled Substances. (1) Each substance that is scheduled or designated as a Schedule I controlled substance under 21 C.F.R. 1308.11, including a substance temporarily scheduled or designated under 21 C.F.R. 1308.11(h) or 1308.49, shall be scheduled or designated at the state level as a Schedule I controlled substance. (2) The Cabinet for Health and Family Services designates the following as Schedule I controlled substances: (a) tianeptine; (b) bromazolam; and (c) 7-hydroxymitragynine (7-OH) concentrated at a level above 400 parts per million on a dry weight basis. This designation does not apply to mitragynine. (3) The following shall be exempt from control as a Schedule I substance: (a) Cannabis plant material, and products made therefrom, that contain tetrahydrocannabinols pursuant to the exemption established in 21 C.F.R. 1308.35; and (b) Any substance or product exempt from the definition of marijuana pursuant to KRS 218A.010(27)(a) – (f).
3cddb56c20a2aa66Each substance that is scheduled or designated as a Schedule I controlled substance under 21 C.F.R. 1308.11, including a substance temporarily scheduled or designated under 21 C.F.R. 1308.11(h) or 1308.49, shall be scheduled or designated at the state level as a Schedule I controlled substance.
7c6da3d222a626acSection 3. Schedule III Controlled Substances. (1) Except as provided by subsection (2) of this section, each substance that is scheduled or designated as a Schedule III controlled substance under 21 C.F.R. 1308.13 shall be scheduled or designated at the state level as a Schedule III controlled substance. (2) The Cabinet for Health and Family Services designates the following as Schedule III controlled substances: (a) Pentazocine; (b) Barbital; (c) Methylphenobarbital; and (d) Phenobarbital. (3) This section shall not apply to any material, compound, mixture, or preparation containing any quantity of an anabolic steroid substance, or any isomer, ester, salt, or derivative thereof that is: (a) Expressly intended for administration through implant to livestock or other nonhuman species; and (b) Approved by the United States Food and Drug Administration for use as described in this subsection.
6772edda9d772e93(8) “Controlled substance” means methamphetamine, or a drug, substance, or
immediate precursor in Schedules I through V and includes a controlled substance
analogue;
(9) (a) "Controlled substance analogue," except as provided in paragraph (b) of this
subsection, means a substance:
1. The chemical structure of which is substantially similar to the structure
of a controlled substance in Schedule I or II; and
2. Which has a stimulant, depressant, or hallucinogenic effect on the
central nervous system that is substantially similar to or greater than the
stimulant, depressant, or hallucinogenic effect on the central nervous
system of a controlled substance in Schedule I or II; or
3. With respect to a particular person, which such person represents or
intends to have a stimulant, depressant, or hallucinogenic effect on the
central nervous system that is substantially similar to or greater than the
stimulant, depressant, or hallucinogenic effect on the central nervous
system of a controlled substance in Schedule I or II.
(b) Such term does not include:
1. Any substance for which there is an approved new drug application;
2. With respect to a particular person, any substance if an exemption is in
effect for investigational use for that person pursuant to federal law to
the extent conduct with respect to such substance is pursuant to such
exemption; or
3. Any substance to the extent not intended for human consumption before
the exemption described in subparagraph 2. of this paragraph takes
effect with respect to that substance;
(1) A person is guilty of possession of a controlled substance in the first degree when
he or she knowingly and unlawfully possesses:
(a) A controlled substance that is classified in Schedules I or II and is a narcotic
drug;
(b) A controlled substance analogue;
(c) Methamphetamine;
(d) Lysergic acid diethylamide;
(e) Phencyclidine;
(f) Gamma hydroxybutyric acid (GHB), including its salts, isomers, salts of
isomers, and analogues; or
(g) Flunitrazepam, including its salts, isomers, and salts of isomers.b4a516b78e2f53ac“Controlled substance” means methamphetamine, or a drug, substance, or immediate precursor in Schedules I through V and includes a controlled substance analogue; (a) "Controlled substance analogue," except as provided in paragraph (b) of this subsection, means a substance: 1. The chemical structure of which is substantially similar to the structure of a controlled substance in Schedule I or II; and 2. Which has a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled substance in Schedule I or II; or 3. With respect to a particular person, which such person represents or intends to have a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled substance in Schedule I or II. (b) Such term does not include: 1. Any substance for which there is an approved new drug application; 2. With respect to a particular person, any substance if an exemption is in effect for investigational use for that person pursuant to federal law to the extent conduct with respect to such substance is pursuant to such exemption; or 3. Any substance to the extent not intended for human consumption before the exemption described in subparagraph 2. of this paragraph takes effect with respect to that substance;
b785931f9bf5b7eb(1) A person is guilty of possession of a controlled substance in the first degree when he or she knowingly and unlawfully possesses: (a) A controlled substance that is classified in Schedules I or II and is a narcotic drug; (b) A controlled substance analogue; (c) Methamphetamine; (d) Lysergic acid diethylamide; (e) Phencyclidine; (f) Gamma hydroxybutyric acid (GHB), including its salts, isomers, salts of isomers, and analogues; or (g) Flunitrazepam, including its salts, isomers, and salts of isomers.
b9c3da9132067b01218A.1450 Trafficking in salvia -- Penalty.
(1) A person is guilty of trafficking in salvia when he or she knowingly and unlawfully
traffics in salvia for human consumption.
(2) Trafficking in salvia is a Class A misdemeanor.bd424db3bd65ad24438.343 Prohibition on sale of nitrous oxide -- Definition -- Exceptions -- Penalties.
(1) As used in this section, "nitrous oxide" means any of the following substances:
(a) N2O;
(b) Dinitrogen monoxide;
(c) Dinitrogen oxide;
(d) Nitrogen oxide;
(e) Butyl nitrite;
(f) Isobutyl nitrite;
(g) Secondary butyl nitrite;
(h) Tertiary butyl nitrite; or
(i) Laughing gas.
(2) A retailer shall not sell, distribute, give away, or cause to be sold any device,
canister, tank, or receptacle that either exclusively contains nitrous oxide or
exclusively contains a chemical compound mixed with nitrous oxide.
(3) Nitrous oxide shall only be available for the uses as authorized by this subsection.
This section shall not prohibit:
(a) The sale or distribution of medical gases that contain nitrous oxide by a
wholesaler licensed by the Kentucky Board of Pharmacy;
(b) Any person who administers nitrous oxide for the purpose of providing
medical or dental care, if administered by a dentist or dental hygienist in
accordance with KRS 313.060;
(c) The possession or use of nitrous oxide substances by a manufacturer as part of
a manufacturing process or industrial operation;
(d) The possession, use, or sale of nitrous oxide as a propellant in food
preparation for restaurant, food service, or houseware products; or
(e) The possession, use, or sale of nitrous oxide for automotive purposes.
(4) Any retailer that violates this section shall be subject to:
(a) A two thousand five hundred dollar ($2,500) fine to the owner of a retail
establishment for a first citation issued for a violation of this section;
(b) A five thousand dollar ($5,000) fine to the owner of a retail establishment for
a second citation issued for a violation of this section; and
(c) Up to thirty (30) days in jail for a third citation issued for a violation of this
section.
(5) Each citation shall be specific to the premises of the retailer where the violation
occurred.
Effective: June 27, 2025
History: Created 2025 Ky. Acts ch. 78, sec. 16, effective June 27, 2025.Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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