Are Psilocybin Mushrooms Legal in Iowa? (2026)

Instrument

Schedule I hallucinogenic substances (official text)

Source

https://www.legis.iowa.gov/docs/code/124.204.pdf

Retrieved

2026-11-01

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schedule, any material, compound, mixture, or preparation, which contains any quantity
of the following hallucinogenic substances, or which contains any of its salts, isomers,
and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is
possible within the specific chemical designation (for purposes of this subsection only, the
term "isomer" includes the optical, position and geometric isomers):

aj. 3,4-Methylenedioxyl-N-methylcathinone (Methylone).
ak. 5-methoxy-N,N-dimethyltryptamine. Some trade or other names:

Instrument

Schedule I, hallucinogenic substances

Source

https://www.legis.iowa.gov/docs/code/124.204.pdf

Retrieved

2026-10-28

Fingerprint

3819178ffcef7a1d

4. Hallucinogenic substances. Unless specifically excepted or unless listed in another
schedule, any material, compound, mixture, or preparation, which contains any quantity
of the following hallucinogenic substances, or which contains any of its salts, isomers,
and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is
possible within the specific chemical designation (for purposes of this subsection only, the
term "isomer" includes the optical, position and geometric isomers):

a. 4-bromo-2,5-dimethoxy-amphetamine. Some trade or other names:

4-bromo-2,5-dimethoxy-a-methylphenethylamine; 4-bromo-2,5-DMA.

b. 2,5-dimethoxyamphetamine. Some trade or other names: 2,5-dimethoxy-a-

methylphenethylamine; 2,5-DMA.

c. 4-methoxyamphetamine. Some trade or other names: 4-methoxy-a-

methylphenethylamine; paramethoxyamphetamine, PMA.

d. 5-methoxy-3,4-methylenedioxy-amphetamine.
e. 4-methyl-2,5-dimethoxyl-amphetamine. Some trade or other names: 4-methyl-2,5-

dimethoxy-a-methylphenethylamine; “DOM”; and “STP”.

f. 3,4-methylenedioxy amphetamine, also known as MDA.
g. 3,4,5-trimethoxy amphetamine.
h. Bufotenine. Some trade or other names: 3-(B-Dimethylaminoethyl)-5-hydroxyindole;

3-(2-dimethylaminoethyl)-5-indolol; N, N-dimethylserotonin; 5-hydroxy-N,N-

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Iowa Code 2026, Section 124.204 (114, 4)

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CONTROLLED SUBSTANCES, §124.204

dimethyltryptamine; mappine.

i. Diethyltryptamine. Some trade or other names: N,N-Diethyltryptamine; DET.
j. Dimethyltryptamine. Some trade or other names: DMT.
k.

Ibogaine. Some trade or other names: 7-Ethyl-6,6B,7,8,9,10,12,13-octahydro-2-
methoxy-6,9-methano-5H-pyrido [1’,2’:1,2] azepino [5,4-b] indole; Tabernanthe iboga.

l. Lysergic acid diethylamide.
m. Marijuana, except as otherwise provided in subsection 7.
n. Mescaline.
o. Parahexyl. Some trade or other names: 3-Hexyl-1-hydroxy-7,8,9,10-tetrahydro-6,6,9-

trimethyl-6H-dibenzo [b,d]pyran; Synhexyl.

p. Peyote, except as otherwise provided in subsection 8. Meaning all parts of the plant
presently classified botanically as Lophophora williamsii Lemaire, whether growing or not,
the seeds thereof, any extract from any part of such plant, and every compound, manufacture,
salt, derivative, mixture, or preparation of such plant, its seeds or extracts.

q. N-ethyl-3-piperidyl benzilate.
r. N-methyl-3-piperidyl benzilate.
s. Psilocybin.
t. Psilocyn.
u. (1) Tetrahydrocannabinols, meaning tetrahydrocannabinols naturally contained in
a plant of the genus Cannabis (Cannabis plant) as well as synthetic equivalents of the
substances contained in the Cannabis plant, or in the resinous extractives of such plant,
and synthetic substances, derivatives, and their isomers with similar chemical structure and
pharmacological activity to those substances contained in the plant, such as the following:

(a) 1 cis or trans tetrahydrocannabinol, and their optical isomers.
(b) 6 cis or trans tetrahydrocannabinol, and their optical isomers.
(c) 3,4 cis or trans tetrahydrocannabinol, and their optical isomers. (Since nomenclature
of these substances is not internationally standardized, compounds of these structures,
regardless of numerical designation of atomic positions covered.)

(2) Subparagraph (1) does not include tetrahydrocannabinol to the extent excluded in

subsection 7.

v. Ethylamine analog of phencyclidine. Some trade or other names: N-ethyl-1-
phenylcyclohexylamine, (1-phenylcyclohexyl)ethylamine, N-(1-phenylcyclohexyl)
ethylamine, cyclohexamine, PCE.

w. Pyrrolidine analog of phencyclidine. Some trade or other names:

1-(1-phenylcyclohexyl)-pyrrolidine, PCPy, PHP.

x. Thiophene analog of phencyclidine. Some trade or other names: 1-[1-(2-thienyl)-

cyclohexyl]-piperidine, 2-thienylanalog of phencyclidine, TPCP, TCP.

y. 1-[1-(2-thienyl)cyclohexyl]pyrrolidine. Some other names: TCPy.
z. 3,4-methylenedioxymethamphetamine (MDMA).
aa. 3,4-methylenedioxy-N-ethylamphetamine (also known as N-ethyl-

alpha-methyl-3,4(methylenedioxy)phenethylamine, N-ethyl MDA, MDE, MDEA).
ab. N-hydroxy-3,4-methylenedioxyamphetamine (also known as N-hydroxy-

alpha-methyl-3,4(methylenedioxy)phenethylamine, and N-hydroxy MDA).

ac. 2,5-dimethoxy-4-ethylamphet-amine. Some trade or other names: DOET.
ad. Alpha-ethyltryptamine.

Some trade or other names:

etryptamine; Monase;

a-ethyl-1H-indole-3-ethanamine; 3-(2-aminobutyl) indole; alpha-ET; and AET.

ae. 4-Bromo-2,5-dimethoxyphenethylamine. Some trade or other names: 2-(4-bromo-

2,5-dimethoxyphenyl)-1-aminoethane; alpha-desmethyl DOB; 2C-B, Nexus.
af. 2,5-dimethoxy-4-(n)-propylthiophenethylamine. Other name: 2C-T-7.
ag. Alpha-methyltryptamine. Other name: AMT.
ah. 5-methoxy-N,N-diisopropyltryptamine. Other name: 5-MeO-DIPT.
ai. (1) Salvia divinorum.
(2) Salvinorin A.
(3) HU-210. [(6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-

yl) 6a,7,10,10a-tetrahydrobenzo[c] chromen-1-ol)].

(4) HU-211(dexanabinol, (6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-

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Iowa Code 2026, Section 124.204 (114, 4)

§124.204, CONTROLLED SUBSTANCES

6

methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c] chromen-1-ol).

(5) Unless specifically exempted or unless listed in another schedule, any material,
compound, mixture, or preparation which contains any quantity of cannabimimetic agents,
or which contains their salts, isomers, and salts of isomers whenever the existence of such
salts, isomers, and salts of isomers is possible within the specific chemical designation.

(a) The term "cannabimimetic agents" means any substance that is a cannabinoid
receptor type 1 (CB1 receptor) agonist as demonstrated by binding studies and functional
assays within any of the following structural classes:

(i) 2-(3-hydroxycyclohexyl)phenol with substitution at the 5-position of the phenolic ring

by alkyl or alkenyl, whether or not substituted on the cyclohexyl ring to any extent.

(ii) 3-(1-naphthoyl)indole or 3-(1-naphthylmethane)indole by substitution at the nitrogen
atom of the indole ring, whether or not further substituted on the indole ring to any extent,
whether or not substituted on the naphthoyl or naphthyl ring to any extent.

(iii) 3-(1-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring,
whether or not further substituted in the pyrrole ring to any extent, whether or not
substituted on the naphthoyl ring to any extent.

(iv) 1-(1-naphthylmethylene)indene by substitution of the 3-position of the indene ring,
whether or not further substituted in the indene ring to any extent, whether or not substituted
on the naphthyl ring to any extent.

(v) 3-phenylacetylindole or 3-benzoylindole by substitution at the nitrogen atom of the
indole ring, whether or not further substituted in the indole ring to any extent, whether or
not substituted on the phenyl ring to any extent.

(b) Such terms include:
(i) 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497).
(ii) 1-pentyl-3-(1-naphthoyl)indole (JWH-018 and AM678).
(iii) 1-butyl-3-(1-naphthoyl)indole (JWH-073).
(iv) 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200).
(v) 1-hexyl-3-(1-naphthoyl)indole (JWH-019).
(vi) 1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH-081).
(vii) 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122).
(viii) 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250).
(ix) RCS-4 and SR-19 1-pentyl-3-[(4methoxy)-benzoyl]indole.
(x) RCS-8 and SR 18 1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole.
(xi) AM2201 1-(5-fluoropentyl)-3-(1-naphthoyl)indole.
JWH-203 1-pentyl-3-(2-chlorophenylacetyl)indole.
(xii)
JWH-398 1-pentyl-3-(4-chloro-1-naphthoyl)indole.
(xiii)
(xiv) AM694 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole.
(xv) 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol

(Cannabicyclohexanol or CP-47,497 C8-homolog).

aj. 3,4-Methylenedioxyl-N-methylcathinone (Methylone).
ak. 5-methoxy-N,N-dimethyltryptamine. Some trade or other names:

5-methoxy-3-[2-(dimethylamino)ethyl]indole; 5-MeO-DMT.
al. 4-methyl-N-ethylcathinone. Other names: 4-MEC, 2-

(ethylamino)-1-(4-methylphenyl)propan-1-one.

am. 4-methyl-alpha-pyrrolidinopropiophenone.

Other names: 4-MePPP, MePPP, 4-methyl-[alpha]-pyrrolidinopropiophenone,
1-(4-methylphenyl)-2-(pyrrolidin-1-yl)-propan-1-one.

an. Alpha-pyrrolidinopentiophenone. Other names: [alpha]-PVP,

[alpha]-pyrrolidinovalerophenone, 1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one.

ao. Butylone. Other names: bk-MBDB, 1-(1,3-benzodioxol-5-yl)-

2-(methylamino)butan-1-one.

ap. Pentedrone. Other names: [alpha]-methylaminovalerophenone,

2-(methylamino)-1-phenylpentan-1-one.

aq. Pentylone. Other names: bk-MBDP, 1-(1,3-benzodioxol-5-yl)-

2-(methylamino)pentan-1-one.

ar. 4-fluoro-N-methylcathinone. Other names: 4-FMC, flephedrone,

Wed Dec 10 22:44:26 2025

Iowa Code 2026, Section 124.204 (114, 4)

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CONTROLLED SUBSTANCES, §124.204

1-(4-fluorophenyl)-2-(methylamino)propan-1-one.

as. 3-fluoro-N-methylcathinone. Other names: 3-FMC, 1-(3-

fluorophenyl)-2-(methylamino)propan-1-one.

at. Naphyrone. Other names: naphthylpyrovalerone,

1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one.

au. Alpha-pyrrolidinobutiophenone. Other names: [alpha]-PBP,

1-phenyl-2-(pyrrolidin-1-yl)butan-1-one.

av. Marijuana extract meaning an extract containing one or more cannabinoids that has
been derived from any plant of the genus Cannabis, containing greater than 0.3 percent
tetrahydrocannabinol on a dry weight basis, other than the separated resin (whether crude
or purified) obtained from the plant.

aw. Any substance, compound, mixture, or preparation which contains any quantity of
any synthetic cathinone that is not approved as a pharmaceutical, including but not limited
to the following:

(1) 4-methylmethcathinone (Mephedrone).
(2) 3,4-methylenedioxypyrovalerone (MDPV).
(3) 4-methoxymethcathinone (methedrone; Bk-PMMA).
(4) 3,4-methylenedioxyethcathinone (ethylone).
(5) N,N-dimethylcathinone(metamfepramone).
(6) Alpha-pyrrolidinopropiophenone (alpha-PPP).
(7) 4-methoxy-alpha-pyrrolidinopropiophenone (MOPPP).
(8) 3,4-methylenedioxy-alpha-pyrrolidinopropiophenone (MDPPP).
(9) 6,7-dihydro-5H-indeno-(5,6-d)-1,3-dioxol-6-amine) (MDAI).
(10) 3-fluoromethcathinone.
(11) 4’-Methyl-alpha-pyrrolidinobutiophenone (MPBP).
(12) 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E).
(13) 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D).
(14) 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C).
(15) 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I).
(16) 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2).
(17) 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4).
(18) 2-(2,5-Dimethoxyphenyl)ethanamine (2C-H).
(19) 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N).
(20) 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C-P).
ax.

(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)

methanone. Other names: UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole.

ay.

[1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-

tetramethylcyclopropyl)methanone. Other names: 5-fluoro-UR-144, 5-F-UR-144, XLR11, 1-
(5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole.

az. N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide.

Other names: APINACA, AKB48.

ba. 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)

ethanamine. Other names: 25I-NBOMe,2C-I-NBOMe, 25I, Cimbi-5.

bb. 2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)

ethanamine. Other names: 25C-NBOMe,2C-C-NBOMe, 25C, Cimbi-82.

bc. 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)

ethanamine. Other names: 25B-NBOMe,2C-B-NBOMe, 25B, Cimbi-36.
bd. Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate. Other names:

PB-22, QUPIC.

be. Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate. Other

names: 5-fluoro-PB-22, 5F-PB-22.

bf. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-

indazole-3-carboxamide. Other names: AB-FUBINACA.

bg. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-

indazole-3-carboxamide. Other name: ADB-PINACA.

bh. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-

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Iowa Code 2026, Section 124.204 (114, 4)

§124.204, CONTROLLED SUBSTANCES

8

1H-indazole-3-carboxamide. Other name: AB-CHMINACA.

bi. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-

carboxamide. Other name: AB-PINACA.

bj.

[1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalene-1-yl)

methanone. Other name: THJ-2201.

bk. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-

(cyclohexylmethyl)-1H-indazole-3-carboxamide. Other names: MAB-CHMINACA;
ADB-CHMINACA.

bl. Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-

dimethylbutanoate. Other names: 5F-ADB; 5F-MDMB-PINACA.

bm. Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-

3-methylbutanoate. Other name: 5F-AMB.

bn. N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-

carboxamide. Other names: 5F-APINACA, 5F-AKB48.

bo. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-

1H-indazole-3-carboxamide. Other name: ADB-FUBINACA.

bp. Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-
dimethylbutanoate. Other names: MDMB-CHMICA, MMB-CHMINACA.
bq. Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-

dimethylbutanoate. Other name: MDMB-FUBINACA.

br. Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-

methylbutanoate. Other names: FUB-AMB, MMB-FUBINACA, AMB-FUBINACA.

bs. methyl

2-(1-(4-fluorobutyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate.

Other names: 4F-MDMB-BINACA, 4F-MDMB-BUTINACA.

bt. 1-(4-methoxyphenyl)-N-methylpropan-2-amine. Other names: para-

methoxymethamphetamine, PMMA.

bu. Naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate. Other names: NM2201

or CBL2201.

bv. N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-

1H-indazole-3-carboxamide. Other name: 5F-AB-PINACA.

bw. 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-

carboxamide. Other names: 4-CN-CUMYL-BUTINACA, 4-cyano-CUMYL-BUTINACA,
4-CN-CUMYL BINACA, CUMYL-4CN-BINACA, or SGT-78.

bx. Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-
methylbutanoate. Other names: MMB-CHMICA or AMB-CHMICA.

by. 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-

pyrrolo[2,3-b]pyridine-3-carboxamide. Other name: 5F-CUMYL-P7AICA.

bz. 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)-pentan-1-one. Other

names: N-ethylpentylone or ephylone.

ca. Ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-

dimethylbutanoate. Other name: 5F-EDMB-PINACA.

cb. Methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-
dimethylbutanoate. Other names: 5F-MDMB-PICA; 5F-MDMB-2201.

cc. N-(adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-

carboxamide. Other names: FUB-AKB48; FUB-APINACA; AKB48 N-(4-FLUOROBENZYL).

cd. 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-

carboxamide. Other names: 5F-CUMYL-PINACA; SGT-25.

ce.

(1-(4-fluorobenzyl)-1H-indol-3-yl) (2,2,3,3-tetramethylcyclopropyl) methanone. Other

name: FUB-144.

cf. 2-(ethylamino)-1-phenylhexan-1-one). Other names: N-Ethylhexedrone;

alpha-ethylaminohexanophenone.

cg. Alpha-Pyrrolidinohexanophenone. Other names: alpha-PHP;

alpha-pyrrolidinohexanophenone; 1-phenyl-2-(pyrrolidin-1-yl)hexan-1-one.
ch. 4-Methyl-alpha-ethylaminopentiophenone. Other names: 4-MEAP;

2-(ethylamino)-1-(4-methylphenyl)pentan-1-one.

ci. 4’-Methyl-alpha-pyrrolidinohexiophenone. Other names: MPHP; 4’-methyl-

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Iowa Code 2026, Section 124.204 (114, 4)

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CONTROLLED SUBSTANCES, §124.204

alpha-pyrrolidinohexanophenone; 1-(4-methylphenyl)-2-(pyrrolidin-1-yl)hexan-1-one.

cj. alpha-Pyrrolidinoheptaphenone. Other names: PV8; 1-phenyl-2-

(pyrrolidin-1-yl)heptan-1-one.

ck. 4’-Chloro-alpha-pyrrolidinovalerophenone. Other names:

4-chloro-alpha-PVP; 4’-chloro-alpha-pyrrolidinopentiophenone; 1-(4-chlorophenyl)-2-
(pyrrolidin-1-yl)pentan-1-one.

cl. 2-(ethylamino)-2-(3-methoxyphenyl)cyclohexan-1-one. Other

names: methoxetamine; MXE.

cm. 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)

butan-1-one. Some trade or other names: eutylone; bk-EBDB.
cn. N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-butyl-1H-

indazole-3-carboxamide. Other name: ADB-BUTINACA.

co. 4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one. Other

name: alpha-PiHP.

cp. 2-(methylamino)-1-(3-methylphenyl)propan-1-one. Other

names: 3-MMC; 3-methylmethcathinone.

Instrument

Nitrous oxide

Source

https://www.legis.iowa.gov/docs/code/2026/126.22.pdf

Retrieved

2026-10-31

Fingerprint

79d245afd23ff27d

126.22 Nitrous oxide.
  1. Unlawful possession. Any person who possesses nitrous oxide or any substance
containing nitrous oxide, with the intent to breathe, inhale, or ingest for the purpose of
causing a condition of intoxication, elation, euphoria, dizziness, stupefaction, or dulling of
the senses, or who knowingly and with the intent to do so is under the influence of nitrous
oxide or any material containing nitrous oxide, is guilty of a serious misdemeanor. This
subsection shall not apply to a person who is under the influence of nitrous oxide or any
material containing nitrous oxide for the purpose of medical, surgical, or dental care by a
person duly licensed to administer such an agent.
  2. Unlawful distribution. Any person who distributes nitrous oxide, or possesses nitrous
oxide with intent to distribute to any other person, if such distribution is with the intent to
induce unlawful inhaling of the substance or is with the knowledge that the other person will
unlawfully inhale the substance, is guilty of a serious misdemeanor.
  97 Acts, ch 39, §6