As of November 3, 2026, MGM-15 (dihydro-7-hydroxymitragynine) is illegal to sell (federally scheduled; state law on file reads illegal) in Louisiana. Federal Schedule I (DEA temporary order, drug code 9673), effective 2026-08-26 to 2028-08-26. Controlling source: LAC 46:LIII.2704 Added Controlled Dangerous Substances (Declaration of Emergency).
Verified November 3, 2026 (hash check) · confidence: confirmedIs MGM-15 Legal? Every state and federal law
Louisiana MGM-15 ban status: ban in force
By Declaration of Emergency under R.S. 40:962(C) and (H), the Louisiana Department of Health, Office of Public Health, adopted LAC 46:LIII.2704, adding mitragynine pseudoindoxyl, MGM-15 and MGM-16 to Schedule I of the Louisiana Uniform Controlled Dangerous Substances Law, including isomers, esters, ethers, salts and any material, compound, mixture or preparation containing any quantity; MGM-15 (dihydro-7-hydroxymitragynine) is named by its chemical name and common name. The rule was published in the October 2026 Louisiana Register (2610#001) and announced by the department on 2026-10-19; it remains in effect for the maximum period allowed for emergency rules or until a final rule is adopted. Also checked: R.S. 40:962(B) directs the secretary to add substances classified as controlled by the DEA, which requires secretary action; R.S. 40:964 Schedule I(G) lists 7-hydroxymitragynine and mitragynine with salts and isomers only, without derivative language; R.S. 40:966.1 defines kratom as any substance derived from the leaves of Mitragyna speciosa or any substance containing 7-hydroxymitragynine or mitragynine and prohibits its manufacture, distribution and possession, which may also reach a semi-synthetic derivative but is not needed for this status; no kratom consumer protection act (HB 778 of 2026, which would have added semi-synthetic language, was not enacted). The Louisiana Register of October 20, 2026 prints no adoption date for the emergency rule; an emergency rule takes effect on adoption (R.S. 49:962(A)(3)) and may run no longer than 180 days (R.S. 49:962(A)(4)) unless a final rule is adopted. Federally, the compound is Schedule I under the DEA temporary scheduling order (DEA-1644, FR Doc. 2026-17429, effective 2026-08-26 to 2028-08-26); that federal control applies regardless of this state row.
2. Methyl (E)-2-((2 S, 3 S, 7 aS, 12 aR, 12 bS)-3-ethyl-7 a -hydroxy-8-methoxy-1,2,3,4,6,7,7 a, 12,12 a, 12 b -decahydroindolo[2,3- a]quinolizin-2-yl)-3-methoxyacrylate (commonly known as MGM-15; also known as dihydro-7-hydroxymitragynine).
Among Louisiana's 3 neighbors, Arkansas, Mississippi and Texas are illegal, the same posture as Louisiana.
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Federally scheduled or prohibited. Federal Schedule I (DEA temporary order, drug code 9673), effective 2026-08-26 to 2028-08-26 Federal detail
6 instruments on file for this compound’s framework in Louisiana; 6 of 6 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
239b952237d06d4aG. Miscellaneous. Unless specifically excepted or contained within a pharmaceutical product approved by the United States Food and Drug Administration, or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including their salts, isomers, or salts of isomers, whenever the existence of such salts, isomers, or salts of isomers is possible within the specific chemical designation: (1) 7-hydroxymitragynine (2) Mitragynine (3) Tianeptine
0e7e25c001c90728§966.1. Unlawful possession, production, or distribution of kratom A. For purposes of this Section, "kratom" means any substance derived from the leaves of the Mitragyna speciosa tree or any substance containing 7-hydroxymitragynine or mitragynine. B.(1) Manufacture; distribution. It shall be unlawful for any person to knowingly produce, manufacture, distribute, or dispense, or possess with intent to produce, manufacture, distribute, or dispense, kratom. (2) Any person who violates Paragraph (1) of this Subsection for an amount of: (a) An aggregate weight of less than five hundred grams, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than three years, or both. (b) An aggregate weight of five hundred grams or more, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than five years, or both. C. Possession. It is unlawful for any person knowingly or intentionally to possess kratom. Any person who violates this Subsection shall be punished as follows: (1) On a conviction wherein the offender possesses twenty grams or less, the offender shall be fined not more than one hundred dollars. (2) On a first conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than five hundred dollars, imprisoned in the parish jail for not more than six months, or both. (3) On a second or any subsequent conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than one thousand dollars, imprisoned in the parish jail for not more than six months, or both. Acts 2025, No. 41, §1.
f452eb21fdac1ada§964. SCHEDULE I — G. Miscellaneous. Unless specifically excepted or contained within a pharmaceutical product approved by the United States Food and Drug Administration, or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including their salts, isomers, or salts of isomers, whenever the existence of such salts, isomers, or salts of isomers is possible within the specific chemical designation: (1) 7-hydroxymitragynine (2) Mitragynine (3) Tianeptine. §966.1. Unlawful possession, production, or distribution of kratom. A. For purposes of this Section, "kratom" means any substance derived from the leaves of the Mitragyna speciosa tree or any substance containing 7-hydroxymitragynine or mitragynine. B.(1) Manufacture; distribution. It shall be unlawful for any person to knowingly produce, manufacture, distribute, or dispense, or possess with intent to produce, manufacture, distribute, or dispense, kratom. (2) Any person who violates Paragraph (1) of this Subsection for an amount of: (a) An aggregate weight of less than five hundred grams, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than three years, or both. (b) An aggregate weight of five hundred grams or more, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than five years, or both. C. Possession. It is unlawful for any person knowingly or intentionally to possess kratom. Any person who violates this Subsection shall be punished as follows: (1) On a conviction wherein the offender possesses twenty grams or less, the offender shall be fined not more than one hundred dollars. (2) On a first conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than five hundred dollars, imprisoned in the parish jail for not more than six months, or both. (3) On a second or any subsequent conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than one thousand dollars, imprisoned in the parish jail for not more than six months, or both. §989.2. C. For the purposes of this Section: (5) "Prohibited plant" means any combination of any of the parts, leaves, stems, stalks, seeds, materials, compounds, salts, derivatives, mixtures, preparations, or any resin extracted from any part of the following plants: (m) Mitragyna speciosa.
52ef0ebfb7c6d526§966.1. Unlawful possession, production, or distribution of kratom A. For purposes of this Section, "kratom" means any substance derived from the leaves of the Mitragyna speciosa tree or any substance containing 7-hydroxymitragynine or mitragynine. B.(1) Manufacture; distribution. It shall be unlawful for any person to knowingly produce, manufacture, distribute, or dispense, or possess with intent to produce, manufacture, distribute, or dispense, kratom. (2) Any person who violates Paragraph (1) of this Subsection for an amount of: (a) An aggregate weight of less than five hundred grams, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than three years, or both. (b) An aggregate weight of five hundred grams or more, shall be fined not more than fifty thousand dollars, imprisoned, with or without hard labor, for not less than one year nor more than five years, or both. C. Possession. It is unlawful for any person knowingly or intentionally to possess kratom. Any person who violates this Subsection shall be punished as follows: (1) On a conviction wherein the offender possesses twenty grams or less, the offender shall be fined not more than one hundred dollars. (2) On a first conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than five hundred dollars, imprisoned in the parish jail for not more than six months, or both. (3) On a second or any subsequent conviction, wherein the offender possesses more than twenty grams, the offender shall be fined not more than one thousand dollars, imprisoned in the parish jail for not more than six months, or both. Acts 2025, No. 41, §1. §989.2. Unlawful production, manufacturing, distribution, or possession of prohibited plant products; exceptions A.(1) It shall be unlawful for any person knowingly or intentionally to produce, manufacture, distribute, or possess with intent to produce, manufacture, or distribute a material, compound, mixture, or preparation which contains a prohibited plant and which meets any of the following criteria: (a) It is intended to be placed in the oral or nasal cavity. (b) It is prepared in such a manner as to be suitable for smoking in a pipe or cigarette, or other device. (c) It is to be burned and inhaled or exhaled in any manner or in any form. (2) Whoever violates the provisions of this Subsection shall be sentenced to a term of imprisonment with or without hard labor for not more than five years and may, in addition, be sentenced to pay a fine of not more than ten thousand dollars. B.(1) It shall be unlawful for any person knowingly or intentionally to possess material, compound, mixture, or preparation which contains a prohibited plant and which is intended to be placed in the oral or nasal cavity, is prepared in such a manner as to be suitable for smoking in a pipe or cigarette, or is to be burned and inhaled or exhaled in any manner or in any form. (2) Any person who violates the provisions of this Subsection shall be fined not more than five hundred dollars, imprisoned for not more than six months, or both. C. For the purposes of this Section: (1) "Distribute" means to sell, barter, trade, furnish, supply, or otherwise transfer in exchange for anything of value a material, compound, mixture, or preparation which contains a prohibited plant. (2) “Homeopathic drug” means any drug labeled as being homeopathic which is listed in the Homeopathic Pharmacopoeia of the United States, an addendum to it, or its supplements. The potencies of homeopathic drugs are specified in terms of dilution. Homeopathic drug products must contain diluents commonly used in homeopathic pharmaceutics. Drug products containing homeopathic ingredients in combination with non-homeopathic active ingredients are not homeopathic drug products. (3) “Manufacture” means the production, preparation, propagation, compounding, or processing of a material, compound, mixture, or preparation which contains a prohibited plant either directly or indirectly by extraction from substances of natural origin, or independently by means of chemical synthesis, or by a combination of extraction and chemical synthesis. Manufacturer includes any person who packages, repackages, or labels any container holding a material, compound, mixture, or preparation which contains a prohibited plant. (4) “Production” includes the manufacture, planting, cultivation, growing, or harvesting of a prohibited plant. (5) "Prohibited plant" means any combination of any of the parts, leaves, stems, stalks, seeds, materials, compounds, salts, derivatives, mixtures, preparations, or any resin extracted from any part of the following plants: (a) Artemisia vulgaris (Mugwort). (b) Canavalia rosea (Bay bean). (c) Leonotis leonurus (Lion's tail). (d) Leonotis nepetifolia (Lion's ear). (e) Leonurus sibiricus (Honeyweed). (f) Mitragyna speciosa. (g) Nelumbo nucifera (Sacred Lotus). (h) Nymphaea caerulea (Blue Lotus, Egyptian Lotus). (i) Pedicularis densiflora (Indian warrior). (j) Salvia divinorum. (k) Scutellaria nana (Dwarf skullcap). (l) Turnera diffusa (Damiana). (m) Zornia latifolia. D. The provisions of this Section shall not apply to any dosage form which is legally obtainable from a retail establishment without a prescription and is recognized by the United States Food and Drug Administration as a homeopathic drug. E. The provisions of this Section shall not apply to the possession, planting, cultivation, growing, or harvesting of a prohibited plant strictly for aesthetic, landscaping, or decorative purposes. F. The provisions of this Section shall not apply to any dosage form which is labeled as a dietary supplement and is manufactured in compliance with the requirements of sections 402(g)(2), 415, and 761 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 342(g)(2), 350d, and 379aa-1). Acts 2010, No. 565, §1; Acts 2015, No. 373, §1, eff. July 1, 2015; Acts 2018, No. 206, §4; Acts 2025, No. 41, §1. G. Miscellaneous. Unless specifically excepted or contained within a pharmaceutical product approved by the United States Food and Drug Administration, or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including their salts, isomers, or salts of isomers, whenever the existence of such salts, isomers, or salts of isomers is possible within the specific chemical designation: (1) 7-hydroxymitragynine (2) Mitragynine (3) Tianeptine
447954c043eaafec3. Methyl (E)-2-((2 S, 3 S, 7 aS, 12 aR, 12b S)-3-ethyl-9- fluoro-7 a -hydroxy-8-methoxy-1,2,3,4,6,7,7 a, 12,12 a, 12 b -decahydroindolo[2,3- a]quinolizin-2-yl)-3-methoxyacrylate (commonly known as MGM-16; also known as 9-fluoro- dihydro-7-hydroxymitragynine; 10-fluoro-dihydro-7- hydroxymitragynine (depending on numbering convention)). listed in Subsection A of internationally standardized, compounds of the listed structures, regardless of numerical designation of atomic positions, are covered and included. B. Since nomenclature of this Section are not the substances or AUTHORITY NOTE: Promulgated in accordance with R.S. 40:962, R.S. 40:963, and R.S. 49:962. HISTORICAL NOTE: Promulgated by the Department of Health, Office of Public Health, LR 52: 2610#001 Bruce D. Greenstein Secretary DECLARATION OF EMERGENCY Department of Health Office of Public Health Added Controlled Dangerous Substances (LAC 46:LIII.2704) The Department of Health, Office of Public Health (LDH/OPH), pursuant to the rulemaking authority granted to the Secretary by R.S. 40:962(C) and (H), hereby adopts the following Emergency Rule for the protection of public health. This rule is being promulgated in accordance with the Administrative Procedure Act (R.S. 49:950, et seq.), particularly R.S. 49:962, and shall remain in effect for the maximum period allowed under the Act or until adoption of a final Rule, whichever occurs first. Based on the criteria, factors, and guidance set forth in R.S. 40:962(C) and 40:963, the secretary, under this rulemaking, has determined that the substances listed below have a high potential for abuse and should be scheduled as controlled dangerous substances under Schedule I to avoid an imminent peril to the public health, safety, or welfare. In reaching the decision to designate the substances listed below as controlled dangerous substances under Schedule I, the secretary has considered the criteria set forth in R.S. 40:963 and the specific factors listed therein. The secretary has determined that Schedule I is the most appropriate due to his findings that the substances added herein have a high potential for abuse, the substances have no currently accepted medical use for treatment in the United States, and there is a lack of accepted safety for use of the substances under medical supervision. In determining that the substances poses an imminent peril to the public health, safety, or welfare, such that they should be added to Schedule I by emergency rule, the secretary has considered the factors set forth in R.S. 40:962(C)(4), (5), and (6). Title 46 PROFESSIONAL AND OCCUPATIONAL STANDARDS Part LIII. Pharmacists Chapter 27. Controlled Dangerous Substances Subchapter A. General Provisions §2704. Added Controlled Dangerous Substances A. Unless specifically excepted or contained within a pharmaceutical product approved by the United States Food and Drug Administration, the following drugs or substances, including any possible isomers, esters, ethers, salts, and salts of isomers, esters, and ethers thereof, and any material, compound, mixture, or preparation which contains any quantity thereof, are added to Schedule I of the Louisiana Uniform Controlled Dangerous Substances Law, R.S. 40:961 et seq.: 1. Methyl (E)-2-((1′ S, 6′ S, 7′S)-6′-ethyl-4-methoxy-3- oxo-3′,5′,6′,7′,8′,8 a ′-hexahydro-2′ H -spiro[indoline-2,1′- indolizine]-7′-yl)-3-methoxyacrylate (commonly known as mitragynine pseudoindoxyl). 2. Methyl (E)-2-((2 S, 3 S, 7 aS, 12 aR, 12 bS)-3-ethyl-7 a -hydroxy-8-methoxy-1,2,3,4,6,7,7 a, 12,12 a, 12 b - decahydroindolo[2,3- a]quinolizin-2-yl)-3-methoxyacrylate (commonly known as MGM-15; also known as dihydro-7- hydroxymitragynine).
084249498b14f5ceDECLARATION OF EMERGENCY Department of Health Office of Public Health Added Controlled Dangerous Substances (LAC 46:LIII.2704) The Department of Health, Office of Public Health (LDH/OPH), pursuant to the rulemaking authority granted to the Secretary by R.S. 40:962(C) and (H), hereby adopts the following Emergency Rule for the protection of public health. This rule is being promulgated in accordance with the Administrative Procedure Act (R.S. 49:950, et seq.), particularly R.S. 49:962, and shall remain in effect for the maximum period allowed under the Act or until adoption of a final Rule, whichever occurs first. Based on the criteria, factors, and guidance set forth in R.S. 40:962(C) and 40:963, the secretary, under this rulemaking, has determined that the substances listed below have a high potential for abuse and should be scheduled as controlled dangerous substances under Schedule I to avoid an imminent peril to the public health, safety, or welfare. In reaching the decision to designate the substances listed below as controlled dangerous substances under Schedule I, the secretary has considered the criteria set forth in R.S. 40:963 and the specific factors listed therein. The secretary has determined that Schedule I is the most appropriate due to his findings that the substances added herein have a high potential for abuse, the substances have no currently accepted medical use for treatment in the United States, and there is a lack of accepted safety for use of the substances under medical supervision. In determining that the substances poses an imminent peril to the public health, safety, or welfare, such that they should be added to Schedule I by emergency rule, the secretary has considered the factors set forth in R.S. 40:962(C)(4), (5), and (6). Title 46 PROFESSIONAL AND OCCUPATIONAL STANDARDS Part LIII. Pharmacists Chapter 27.Controlled Dangerous Substances Subchapter A.General Provisions §2704.Added Controlled Dangerous Substances A. Unless specifically excepted or contained within a pharmaceutical product approved by the United States Food and Drug Administration, the following drugs or substances, including any possible isomers, esters, ethers, salts, and salts of isomers, esters, and ethers thereof, and any material, compound, mixture, or preparation which contains any quantity thereof, are added to Schedule I of the Louisiana Uniform Controlled Dangerous Substances Law, R.S. 40:961 et seq.: 1. Methyl (E)-2-((1′ S, 6′ S, 7′S)-6′-ethyl-4-methoxy-3-oxo-3′,5′,6′,7′,8′,8 a ′-hexahydro-2′ H -spiro[indoline-2,1′-indolizine]-7′-yl)-3-methoxyacrylate (commonly known as mitragynine pseudoindoxyl). 2. Methyl (E)-2-((2 S, 3 S, 7 aS, 12 aR, 12 bS)-3-ethyl-7 a -hydroxy-8-methoxy-1,2,3,4,6,7,7 a, 12,12 a, 12 b -decahydroindolo[2,3- a]quinolizin-2-yl)-3-methoxyacrylate (commonly known as MGM-15; also known as dihydro-7-hydroxymitragynine). 3. Methyl (E)-2-((2 S, 3 S, 7 aS, 12 aR, 12b S)-3-ethyl-9-fluoro-7 a -hydroxy-8-methoxy-1,2,3,4,6,7,7 a, 12,12 a, 12 b -decahydroindolo[2,3- a]quinolizin-2-yl)-3-methoxyacrylate (commonly known as MGM-16; also known as 9-fluoro-dihydro-7-hydroxymitragynine; or 10-fluoro-dihydro-7-hydroxymitragynine (depending on numbering convention)). B. Since nomenclature of the substances listed in Subsection A of this Section are not internationally standardized, compounds of the listed structures, regardless of numerical designation of atomic positions, are covered and included. AUTHORITY NOTE:Promulgated in accordance with R.S. 40:962, R.S. 40:963, and R.S. 49:962. HISTORICAL NOTE:Promulgated by the Department of Health, Office of Public Health, LR 52: Bruce D. Greenstein Secretary 2610#001
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