Are Nicotine Vapes (e-cigarettes) Legal in Texas? (2026)

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2025 annual republication of Texas schedules of controlled substances

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https://www.sos.state.tx.us/texreg/archive/November142025/In%20Addition/202503976-1.pdf

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2026-11-02

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PURSUANT TO THE TEXAS CONTROLLED SUBSTANCES ACT, HEALTH AND 
SAFETY CODE, CHAPTER 481, THESE SCHEDULES SUPERCEDE PREVIOUS 
SCHEDULES AND CONTAIN THE MOST CURRENT VERSION OF THE 
SCHEDULES OF ALL CONTROLLED SUBSTANCES FROM THE PREVIOUS 
SCHEDULES AND MODIFICATIONS.  
This annual publication of the Texas Schedules of Controlled Substances was 
signed by Jennifer A. Shuford, M.D., M.P.H., Commissioner of Health, and 
will take effect 21 days following publication of this notice in the Texas 
Register. 
Changes to the schedules are designated by an asterisk (*). Additional 
information can be obtained by contacting the Department of State Health 
Services, Drugs and Medical Devices Branch, P.O. Box 149347, Austin, Texas 
78714-9347. The telephone number is (512) 834-6755  
and the website address is http://www.dshs.texas.gov/dmd. 
SCHEDULES 
Nomenclature: Controlled substances listed in these schedules are included 
by whatever official, common, usual, chemical, or trade name they may be 
designated. 
SCHEDULE I 
Schedule I consists of: 
-Schedule I Opiates 
The following opiates, including their isomers, esters, ethers, salts, and salts 
of isomers, esters, and ethers, unless specifically excepted, if the existence 
of these isomers, esters, ethers, and salts are possible within the specific 
chemical designation: 
(1) Acetyl-α-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl]-N­
phenylacetamide); 
(2) Acetylmethadol; 
(3) Acetyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide); 
(4) Acryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide) 
(Other name: acryloylfentanyl); 
(5) AH-7921 (3,4-dichloro-N-[1-(dimethylamino) 
cyclohexymethyl]benzamide); 
(6) Allylprodine; 
(7) Alphacetylmethadol (except levo-α-cetylmethadol, levo-α­
acetylmethadol, levomethadyl acetate, or LAAM); 
(8) α′-Methyl butyryl fentanyl (2-methyl-N-(1-phenethylpiperidin-4-yl)-N­
phenylbutanamide); 

 
 
 
 
 
 
 
 
 
(9) α-Methylfentanyl or any other derivative of fentanyl; 
(10) α-Methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4-piperidinyl] N­
phenylpropanamide); 
(11) Benzethidine; 
(12) β-Hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4-piperidinyl]-N­
phenylpropanamide); 
(13) β-Hydroxy-3-methylfentanyl (N-[1-(2-hydroxy-2-phenethyl)-3-methyl­
4-piperidinyl]-N-phenylpropanamide); 
(14) β-hydroxythiofentanyl (Other names: N-[1-[2-hydroxy-2-(thiophen-2­
yl)ethyl]piperidin-4-yl]-N-phenylproprionamide; N-[1-[2-hydroxy-2-(2­
thienyl)ethyl]-4-piperidnyl]-N-phenylpropanamide); 
(15) β-Methyl fentanyl (N-phenyl-N-(1-(2-phenylpropyl)piperidin-4­
yl)propionamide); 
(16) β′-Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N,3­
diphenylpropanamide) (Other name: 3-phenylpropanoyl fentanyl); 
(17) Betaprodine; 
(18) Brorphine (1–(1–(1–(4-bromophenyl)ethyl)piperidin-4–yl)–1,3-dihydro­
2H-benzo[d]imidazol-2-one); 
*(19) Butonitazene (2-(2-(4-butoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)­
N,N-diethylethan-1-amine); 
(20) Butyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbutanamide); 
(21) Clonitazene; 
*(22) Crotonyl fentanyl (Other name: (E)-N-(1-Phenethylpiperidin-4-yl)-N­
phenylbut-2-enamide); 
(23) Cyclopentyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-
Phenylcyclopentanecarboxamide);  
(24) Cyclopropyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenylcyclopropanecarboxamide); 
(25) Diampromide; 
(26) Diethylthiambutene; 
(27) Difenoxin; 
(28) Dimenoxadol; 
(29) 2′,5′-Dimethoxyfentanyl (N-(1-(2,5-dimethoxyphenethyl)piperidin-4­
yl)-N-phenylpropionamide); 
(30) Dimethylthiambutene; 
(31) Dioxaphetyl butyrate; 
(32) Dipipanone; 
(33) Ethylmethylthiambutene; 
*(34) 2-(2-(4-ethoxybenzyl)-1H-benzimidazol-1-yl)-N,N-diethylethan-1­
amine (Other names: etodesnitazene; etazene); 
(35) Etonitazene; 
(36) Etoxeridine; 
(37) Fentanyl carbamate (ethyl (1-phenethylpiperidin-4­
yl)(phenyl)carbamate); 
*(38) Flunitazene (N,N-diethyl-2-(2-(4-fluorobenzyl)-5-nitro-1H­
benzimidazol-1-yl)ethan-1-amine); 
(39) 4-Fluoroisobutyryl fentanyl (N-(4-fluorophenyl)-N-(1­
phenethylpiperidin-4-yl)isobutyramide) (Other name: p-fluoroisobutyryl 
fentanyl); 

 
 
 
 
 
 
 
(40) 2′-Fluoro o-fluorofentanyl (N-(1-(2-fluorophenethyl)piperidin-4-yl)-N­
(2-fluorophenyl)propionamide) (Other name: 2′-fluoro 2-fluorofentanyl); 
(41) Furanyl fentanyl (N-(1-phenethylpiperdin-4-yl)-N-phenylfuran-2­
carboxamide); 
(42) 3-Furanyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-3­
carboxamide); 
(43) Furethidine; 
(44) Hydroxypethidine; 
(45) Isobutyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenylisobutyramide); 
(46) Isotonitazene (N,N-diethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H­
benzimidazol-1-yl)ethan-1-amine); 
(47) Isovaleryl fentanyl (3-methyl-N-(1-phenethylpiperidin-4-yl)-N­
phenylbutanamide); 
(48) Ketobemidone; 
(49) Levophenacylmorphan; 
(50) m-Fluorofentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide); 
(51) m-Fluoroisobutyryl fentanyl (N-(3-fluorophenyl)-N-(1­
phenethylpiperidin-4-yl)isobutyramide); 
(52) Meprodine; 
(53) Methadol; 
(54) Methoxyacetyl fentanyl (2-methoxy-N-(1-phenethylpiperidin-4-yl)-N­
phenylacetamide); 
*(55) 2-Methyl AP-237 (1-(2-methyl-4-(3-phenylprop-2-en-1-yl)piperazin-1­
yl)butan-1-one); 
(56) 4′-Methyl acetyl fentanyl (N-(1-(4-methylphenethyl)piperidin-4-yl)-N­
phenylacetamide); 
(57) 3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-piperidyl]-N-
phenylpropanamide);  
(58) 3-Methylthiofentanyl (N-[3-methyl-1-(2-thienyl)ethyl-4-piperidinyl]-N­
phenylpropanamide); 
*(59) Metodesnitazene (N,N-diethyl-2-(2-(4-methoxybenzyl)-1H­
benzimidazol-1-yl)ethan-1-amine); 
(60) Metonitazene (N,N-diethyl-2-(2-(4-methoxybenzyl)-5-nitro-1H­
benzimidazol-1-yl)ethan-1-amine); 
(61) Moramide; 
(62) Morpheridine; 
(63) MPPP (1-methyl-4-phenyl-4-propionoxypiperidine);  
(64) MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine); 
(65) Noracymethadol; 
(66) Norlevorphanol; 
(67) Normethadone; 
(68) Norpipanone; 
*(69) 2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H­
benzimidazole (other names: N-pyrrolidino etonitazene; etonitazepyne); 
(70) Ocfentanil (N-(2-fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4­
yl)acetamide); 
(71) o-Fluoroacryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)acrylamide); 

 
 
 
 
 
 
(72) o-Fluorobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)butyramide) (Other name:2-fluorobutyryl fentanyl); 
(73) o-Fluorofentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide) (Other name: 2-fluorofentanyl); 
(74) o-Fluorofuranyl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide); 
(75) o-Fluoroisobutyryl fentanyl (N-(2-fluorophenyl)-N-(1­
phenethylpiperidin-4-yl)isobutyramide); 
(76) o-Methyl acetylfentanyl (N-(2-methylphenyl)-N-(1-phenethylpiperidin­
4-yl)acetamide) (Other name: 2-methyl acetylfentanyl); 
(77) o-Methyl methoxyacetyl fentanyl (2-methoxy-N-(2-methylphenyl)-N-(1­
phenethylpiperidin-4-yl)acetamide) (Other name: 2-methyl methoxyacetyl 
fentanyl); 
(78) p-Chloroisobutyryl fentanyl (N-(4-chlorophenyl)-N-(1- 
phenethylpiperidin-4-yl)isobutyramide); 
(79) p-Fluorobutyryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin­
4-yl)butyramide); 
(80) p-Fluorofentanyl (N-(4-fluorophenyl)-N-[1-(2-phenethyl)-4 piperidinyl] 
propanamide); 
(81) p-Fluoro furanyl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin­
4-yl)furan-2-carboxamide); 
(82) p-Methoxybutyryl fentanyl (N-(4-methoxyphenyl)-N-(1-
phenethylpiperidin-4-yl)butyramide; 
(83) p-Methoxyfuranyl fentanyl (N-(4-methoxyphenyl)-N-(1­
phenethylpiperidin-4-yl)furan-2-carboxamide); 
(84) p-Methylcyclopropyl fentanyl (N-(4-methylphenyl)-N-(1­
phenethylpiperidin-4-yl)cyclopropanecarboxamide); 
(85) p-Methylfentanyl (N-(4-methylphenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide) (Other name: 4-methylfentanyl); 
(86) PEPAP (1-(2-phenethyl)-4-phenyl-4-acetoxypiperidine); 
(87) Phenadoxone; 
(88) Phenampromide; 
(89) Phencyclidine; 
(90) Phenomorphan; 
(91) Phenoperidine; 
(92) Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbenzamide) 
(Other name: benzoyl fentanyl); 
(93) Piritramide; 
(94) Proheptazine; 
(95) Properidine; 
(96) Propiram; 
*(97) N,N-diethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1­
yl)ethan-1-amine (other name: protonitazene); 
(98) Tetrahydrofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenyltetrahydrofuran-2-carboxamide); 
(99) Thiofentanyl (N-phenyl-N-[1-(2-thienyl)ethyl-4-piperidinyl]­
propanamide); 
(100) Thiofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenylthiophene-2-carboxamide) (Other names: 2-thiofuranyl fentanyl; 
thiophene fentanyl); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(101) Tilidine; 
(102) Trimeperidine; 
(103) U-47700 (3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N­
methylbenzamide); 
(104) Valeryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenylpentanamide); and, 
(105) Zipeprol (1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]­
1-phenylpropan-2-ol). 
-Schedule I Opium Derivatives 
The following opium derivatives, their salts, isomers, and salts of isomers, 
unless specifically excepted, if the existence of these salts, isomers, and 
salts of isomers is possible within the specific chemical designation: 
(1) Acetorphine; 
(2) Acetyldihydrocodeine; 
(3) Benzylmorphine; 
(4) Codeine methylbromide; 
(5) Codeine-N-Oxide; 
(6) Cyprenorphine; 
(7) Desomorphine; 
(8) Dihydromorphine; 
(9) Drotebanol; 
(10) Etorphine (except hydrochloride salt); 
(11) Heroin; 
(12) Hydromorphinol; 
(13) Methyldesorphine; 
(14) Methyldihydromorphine; 
(15) Monoacetylmorphine; 
(16) Morphine methylbromide; 
(17) Morphine methylsulfonate; 
(18) Morphine-N-Oxide; 
(19) Myrophine; 
(20) Nicocodeine; 
(21) Nicomorphine; 
(22) Normorphine; 
(23) Pholcodine; and 
(24) Thebacon. 
-Schedule I Hallucinogenic Substances 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the 
following hallucinogenic substances or that contains any of the substance's 
salts, isomers, and salts of isomers if the existence of the salts, isomers, and 
salts of isomers is possible within the specific chemical designation (for the 
purposes of this Schedule I hallucinogenic substances section only, the term 
"isomer" includes optical, positional, and geometric isomers):  

 
 
 
 
 
 
 
 
 
 
 
(1) α-Ethyltryptamine (Other names: etryptamine; Monase; α-ethyl­
1H-indole-3-ethanamine; 3-(2-aminobutyl) indole; α-ET; AET); 
 
(2) 4-Bromo-2,5-dimethoxyamphetamine (Other names: 4-bromo­
2,5-dimethoxy-α-methylphenethylamine; 4-bromo-2,5-DMA); 
(3) 4-Bromo-2,5-dimethoxyphenethylamine (Other names: Nexus; 2C­
B; 2-(4-bromo-2,5-dimethoxyphenyl)-1-aminoethane; α-desmethyl DOB); 
(4) 2,5-Dimethoxyamphetamine (Other names: 2,5-dimethoxy-α­
methylphenethylamine; 2,5-DMA); 
(5) 2,5-Dimethoxy-4-ethylamphetamine (Other name: DOET);  
(6) 2,5-Dimethoxy-4-(n)-propylthiophenethylamine, its optical 
isomers, salts and salts of isomers (Other name: 2C-T-7);  
(7) 4-Methoxyamphetamine (Other names: 4-methoxy-α­
methylphenethylamine; paramethoxyamphetamine; PMA); 
(8) 5-Methoxy-3,4-methylenedioxyamphetamine (Other name: 
MMDA); 
(9) 4-Methyl-2,5-dimethoxyamphetamine (Other names: 
4-methyl-2,5-dimethoxy-α-methyl-phenethylamine; “DOM”;“STP”); 
(10) 3,4-Methylenedioxyamphetamine (Other names: MDA; Love 
Drug); 
(11) 3,4-Methylenedioxymethamphetamine (Other names: MDMA; 
MDM; Ecstasy; XTC); 
(12) 3,4-Methylenedioxy-N-ethylamphetamine (Other names: N-ethyl-
α-methyl-3,4(methylenedioxy)phenethylamine; N-ethyl MDA; MDE; MDEA); 
(13) N-Hydroxy-3,4-methylenedioxyamphetamine (Other name: N-
hydroxy MDA); 
(14) 3,4,5-Trimethoxyamphetamine (Other name: TMA); 
(15) 5-Methoxy-N,N-dimethyltryptamine (Other names: 5-methoxy-3­
[2-(dimethylamino)ethyl]indole; 5-MeO-DMT); 
(16) α-Methyltryptamine (Other name: AMT); 
(17) Bufotenine (Other names: 3-β-Dimethylaminoethyl)-5- 
hydroxyindole; 3-(2-dimethylaminoethyl)-5-indolol; N,N-dimethylserotonin; 
5-hydroxy-N,N-dimethyltryptamine; mappine); 
(18) Diethyltryptamine (Other names: N,N-Diethyltryptamine; DET); 
(19) Dimethyltryptamine (Other name: DMT); 
(20) 5-Methoxy-N,N-diisopropyltryptamine (Other name: 5-MeO-
DIPT); 
(21) Ibogaine (Other names: 7-Ethyl-6,6-β-7,8,9,10,12,13-octhydro­
2-methoxy-6,9-methano-5H-pyrido[1′,2′:1,2] azepino [5,4-b] indole; 
Tabernanthe iboga); 
(22) Lysergic acid diethylamide; 
(23) Marihuana, the term marihuana does not include hemp, as 
defined in Title 5, Agriculture Code, Chapter 121; 
(24) Mescaline; 
(25) Parahexyl (Other names: 3-Hexyl-1-hydroxy-7,8,9,10-tetrahydro­
6,6,9-trimethyl-6H-dibenzo[b,d]pyran; Synhexyl); 
(26) Peyote, unless unharvested and growing in its natural state, 
meaning all parts of the plant classified botanically as Lophophora williamsii 
Lemaire, whether growing or not, the seeds of the plant, an extract from a 
part of the plant, and every compound, manufacture, salt, derivative, 
mixture, or preparation of the plant, its seeds, or extracts; 

 
 
 
 
 
 
 
 
(27) N-ethyl-3-piperidyl benzilate; 
(28) N-methyl-3-piperidyl benzilate; 
(29) Psilocybin; 
(30) Psilocyn; 
(31) Tetrahydrocannabinols, meaning tetrahydrocannabinols naturally 
contained in a plant of the genus Cannabis (cannabis plant), except for 
tetrahydrocannabinols in hemp (as defined under Section 297A(1) of the 
Agricultural Marketing Act of 1946), as well as synthetic equivalents of the 
substances contained in the cannabis plant, or in the resinous extractives of 
such plant, and/or synthetic substances, derivatives, and their isomers with 
similar chemical structure and pharmacological activity to those substances 
contained in the plant, such as the following: 
1 cis or trans tetrahydrocannabinol, and their optical isomers; 
6 cis or trans tetrahydrocannabinol, and their optical isomers; 
3,4 cis or trans tetrahydrocannabinol, and its optical isomers;  
(Since nomenclature of these substances is not internationally 
standardized, compounds of these structures, regardless of numerical 
designation of atomic positions covered.) 
(32) Ethylamine analog of phencyclidine (Other names: 
N-ethyl-1-phenylcyclohexylamine; (1-phenylcyclohexyl)ethylamine; 
N-(1-phenylcyclohexyl)ethylamine; cyclohexamine; PCE); 
(33) Pyrrolidine analog of phencyclidine (Other names: 1-(1 phenyl- 
cyclohexyl)-pyrrolidine; PCPy; PHP; rolicyclidine); 
(34) Thiophene analog of phencyclidine (Other names: 1-[1-(2­
thienyl)-cyclohexyl]-piperidine; 2-thienyl analog of phencyclidine; TPCP; 
TCP); 
(35) 1-[1-(2-Thienyl)cyclohexyl]pyrrolidine (Other name: TCPy); 
(36) 4-Methylmethcathinone (Other names: 4-methyl-N­
methylcathinone; mephedrone); 
(37) 3,4-Methylenedioxypyrovalerone (Other name: MDPV); 
(38) 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (Other name: 2C­
E); 
(39) 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (Other name: 2C­
D); 
(40) 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (Other name: 2C­
C); 
(41) 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (Other name: 2C-I);  
(42) 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (Other name: 
2C-T-2); 
(43) 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (Other 
name: 2C-T-4); 
(44) 2-(2,5-Dimethoxyphenyl)ethanamine (Other name: 2C-H);  
(45) 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (Other name: 2C­
N); 
(46) 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (Other name: 
2C-P); 
(47) 3,4-Methylenedioxy-N-methylcathinone (Other name: 
Methylone); 

 
 
 
 
 
 
 
(48) (1-Pentyl-1H-indol-3-yl)(2,2,3,3­
tetramethylcyclopropyl)methanone (Other names: UR-144; 1-pentyl-3­
(2,2,3,3-tetramethylcyclopropoyl)indole); 
(49) [1-(5-Fluoro-pentyl)-1H-indol-3-yl](2,2,3,3­
tetramethylcyclopropyl)methanone (Other names: 5-fluoro-UR-144; 5-F-UR­
144; XLR11; (5-flouro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole); 
(50) N-(1-Adamantyl)-1-pentyl-1H-indazole-3-carboxamide (Other 
names: APINACA; AKB48); 
(51) Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (Other names: 
PB-22; QUPIC); 
(52) Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (Other 
names: 5-fluoro-PB-22; 5F-PB-22); 
(53) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H­
indazole-3-carboxamide (Other name: AB-FUBINACA); 
(54) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole­
3-carboxamide (Other name: ADB-PINACA); 
(55) 2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2­
methoxybenzyl)ethanamine (Other names: 25I-NBOMe; 2CI-NBOMe; 25I; 
Cimbi-5); 
(56) 2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2­
methoxybenzyl)ethanamine (Other names: 25C-NBOMe; 2C-C-NBOMe; 25C; 
Cimbi-82); 
(57) 2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2­
methoxybenzyl)ethanamine (Other names: 25B-NBOMe; 2C-B-NBOMe; 25B; 
Cimbi-36); 
(58) Marihuana extract, meaning an extract containing one or more 
cannabinoids that has been derived from any plant of the genus Cannabis, 
other than separated resin (whether crude or purified) obtained from the 
plant; 
(59) 4-Methyl-N-ethylcathinone (Other name: 4-MEC); 
(60) 4-Methyl-α-pyrrolidinopropiophenone (Other name: 4-MePPP); 
(61) α-Pyrrolidinopentiophenone (Other name: [α]-PVP); 
(62) 1-(1,3-Benzodioxol-5-yl)-2-(methylamino)butan-1-one  
(Other names: butylone; bk-MBDB); 
(63) 2-(Methylamino)-1-phenylpentan-1-one (Other name: 
pentedrone); 
(64) 1-(1,3-Benzodioxol-5-yl)-2-(methylamino)pentan-1-one  
(Other names: pentylone; bk-MBDP); 
(65) 4-Fluoro-N-methylcathinone (Other names: 4-FMC; flephedrone); 
(66) 3-Fluoro-N-methylcathinone (Other name: 3-FMC); 
(67) 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (Other 
name: naphyrone);  
(68) α-Pyrrolidinobutiophenone (Other name: α-PBP); 
(69) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H­
indazole-3-carboxamide (Other name: AB-CHMINACA);  
(70) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3­
carboxamide (Other name: AB-PINACA); 
(71) [1-(5-Fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone 
(Other name: THJ-2201); 

 
 
 
 
 
(72) 1-Methyl-4-phenyl-1,2,5,6-tetrahydro-pyridine (Other name: 
MPTP); 
(73) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexyl­
methyl)-1H-indazole-3-carboxamide (Other names: MAB-CHMINACA; ABD­
CHMINACA); 
(74) Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: 5F-ADB; 5F-MDMB-PINACA); 
(75) Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-caboxamido)-3­
methylbutanoate (Other name: 5F-AMB); 
(76) N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3­
carboxamide (Other names: 5F-APINACA; 5F-AKB48); 
(77) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)­
1H-indazole-3-carboxamide (Other name: ADB-FUBINACA); 
(78) Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: MDMB-CHMICA; MMB-CHMINACA); 
(79) Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other name: MDMB-FUBINACA); 
(80) Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3­
methylbutanoate (Other names: FUB-AMB; MMB-FUBINACA; AMB­
FUBINACA); 
(81) Naphthalen-1-yl-1-(5-fluoropentyl)-1H-indole-3-carboxylate 
(Other names: NM2201; CBL2201); 
(82) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H­
indazole-3-carboxamide (Other name: 5F-AB-PINACA); 
(83) 1-(4-Cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3­
carboxamide (Other names: 4-CN-CUMYL-BUTINACA; 4-cyano-CUMYL­
BUTINACA; 4-CN-CUMYL-BINACA; CUMYL-4CN-BINACA; SGT-78); 
(84) Methyl 2-(1-(Cyclohexylmethyl)-1H-indole-3-carboxamido)-3­
methylbutanoate (Other names: MMB-CHMICA; AMB-CHMICA); 
(85) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3­
b]pyridine-3-carboxamide (Other name: 5F-CUMYL-P7AICA); 
(86) 1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)pentan-1-one (Other 
names: N-ethylpentylone; ephylone); 
(87) Methyl 2-(1-(4-fluorobutyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate) (Other names: 4F-MDMB-BINACA; 4F-MDMB­
BUTINACA); 
(88) 1-(4-Methoxyphenyl)-N-methylpropan-2-amine (Other names: p­
methoxymethamphetamine; PMMA);  
(89) Ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other name: 5F-EDMB-PINACA);  
(90) Methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: 5F-MDMB-PICA; 5F-MDMB-2201); 
(91) N-(Adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3­
carboxamide (Other names: FUB-AKB48; FUB-APINACA; AKB48 N-(4­
fluorobenzyl)); 
(92) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3­
carboxamide (Other names: 5F-CUMYL-PINACA; SGT-25); 
(93) (1-(4-Fluorobenzyl)-1H-indol-3-yl)(2,2,3,3­
tetramethylcyclopropyl)methanone (Other name: FUB-144);  

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(94) N-Ethylhexedrone (Other name: 2-(ethylamino)-1-phenylhexan­
1-one); 
(95) α-Pyrrolidinohexanophenone (Other names: α-PHP; α­
pyrrolidinohexiophenone; 1-phenyl-2-(pyrrolidin-1-yl)hexan-1-one); 
 
(96) 4-Methyl-α-ethylaminopentiophenone (Other names: 4–MEAP; 2­
(ethylamino)-1-(4-methylphenyl)pentan-1-one); 
(97) 4′-Methyl-α-pyrrolidinohexiophenone (Other names: MPHP; 4′­
methyl-α-pyrrolidinohexanophenone; 1-(4-methylphenyl)-2-(pyrrolidin-1­
yl)hexan-1-one); 
(98) α-Pyrrolidinoheptaphenone (Other names: PV8; 1-phenyl-2­
(pyrrolidin-1-yl)heptan-1-one); 
(99) 4′-Chloro-α-pyrrolidinovalerophenone (Other names: 4-chloro-α­
PVP; 4′-chloro-α-pyrrolidinopentiophenone; 1-(4-chlorophenyl)-2­
(pyrrolidin-1-yl)pentan-1-one); 
 
(100) 2-(ethylamino)-2-(3-methoxyphenyl)cyclohexan-1-one (Other 
names: methoxetamine; MXE); and, 
 
(101) 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)butan-1-one (Other 
names: eutylone; bk-EBDB). 
-Schedule I Depressants 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the 
following substances having a depressant effect on the central nervous 
system, including the substance's salts, isomers, and salts of isomers if the 
existence of the salts, isomers, and salts of isomers is possible within the 
specific chemical designation: 
(1) Gamma-hydroxybutyric acid (Other names: GHB; gamma­
hydroxybutyrate; 4-hydroxybutyrate; 4-hydroxybutanoic acid; sodium 
oxybate; sodium oxybutyrate); 
(2) Mecloqualone; and
 
(3) Methaqualone. 
-Schedule I Stimulants 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the 
following substances having a stimulant effect on the central nervous 
system, including the substance's salts, isomers, and salts of isomers if the 
existence of the salts, isomers, and salts of isomers is possible within the 
specific chemical designation: 
(1) Amineptine 7-((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5­
yl)amino)heptanoic acid; 
(2) Aminorex (Other names: aminoxaphen; 2-amino-5-phenyl-2­
oxazoline; 4,5-dihydro-5-phenyl-2-oxazolamine); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(3) N-Benzylpiperazine (Other names: BZP; 1-benzylpiperazine), its 
optical isomers, salts and salts of isomers; 
(4) Cathinone (Other names: 2-amino-1-phenyl-1-propanone; α­
aminopropiophenone; 2-aminopropiophenone; norephedrone); 
 
(5) 4,4′-Dimethylaminorex (4,4′-DMAR; 4,5-dihydro-4-methyl-5-(4­
methylphenyl)-2-oxazolamine; 4-methyl-5-(4-methylphenyl)-4,5-dihydro­
1,3-oxazol-2-amine); 
*(6) Ethylphenidate (ethyl 2-phenyl-2-(piperidin-2-yl)acetate); 
(7) Fenethylline; 
(8) Methcathinone (Other names: 2-(methylamino)-propiophenone; α­
(methylamino)propiophenone; 2-(methylamino)-1-phenylpropan-1-one; α­
N-methylaminopropiophenone; monomethylpropion; ephedrone; N­
methylcathinone; methylcathinone; AL-464; AL-422; AL-463; UR1432);  
(9) Mesocarb N-phenyl-N’–(3-(1-phenylpropan-2-yl)-1,2,3-oxadiazol­
3-ium-5-yl)carbamimidate);
 
(10) Methiopropamine N-methyl-1-(thiophen-2yl)propan-2-amine; 
(11) 4-Methylaminorex (Other names: U4Euh; McN-422); 
(12) N-Ethylamphetamine; and 
(13) N,N-Dimethylamphetamine (Other names: N,N-α­
trimethylbenzene-ethaneamine; N,N-α-trimethylphenethylamine). 
-Schedule I Cannabimimetic Agents 
Unless specifically exempted or unless listed in another schedule, any 
material, compound, mixture, or preparation which contains any quantity of 
cannabimimetic agents, or which contains their salts, isomers, and salts of 
isomers whenever the existence of such salts, isomers, and salts of isomers 
is possible within the specific chemical designation: 
(1) The term 'cannabimimetic agents' means any substance that is a 
cannabinoid receptor type 1 (CB1 receptor) agonist as demonstrated by 
binding studies and functional assays within any of the following structural 
classes:
 
 
(1-1) 2-(3-Hydroxycyclohexyl)phenol with substitution at the 
5-position of the phenolic ring by alkyl or alkenyl, whether or not substituted 
on the cyclohexyl ring to any extent; 
(1–2) 3-(1-Naphthoyl)indole or 3-(1-naphthylmethane)indole 
by substitution at the nitrogen atom of the indole ring, whether or not 
further substituted on the indole ring to any extent, whether or not 
substituted on the naphthoyl or naphthyl ring to any extent; 
(1–3) 3-(1-Naphthoyl)pyrrole by substitution at the nitrogen 
atom of the pyrrole ring, whether or not further substituted in the pyrrole 
ring to any extent, whether or not substituted on the naphthoyl ring to any 
extent; 
(1–4) 1-(1-Naphthylmethylene)indene by substitution of the 
3-position of the indene ring, whether or not further substituted in the 
indene ring to any extent, whether or not substituted on the naphthyl ring to 
any extent; and, 
(1-5) 3-Phenylacetylindole or 3-benzoylindole by substitution 
at the nitrogen atom of the indole ring, whether or not further substituted in 

 
 
        
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
the indole ring to any extent, whether or not substituted on the phenyl ring 
to any extent. 
(2) 5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol 
(Other name: CP-47,497); 
 
(3) 5-(1,1-Dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol 
(Other names: cannabicyclohexanol, CP-47,497 C8 homolog); 
(4) 1-Pentyl-3-(1-naphthoyl)indole (Other names: JWH-018; 
AM678); 
(5) 1-Butyl-3-(1-naphthoyl)indole (Other name: JWH-073); 
(6) 1-Hexyl-3-(1-naphthoyl)indole (Other name: JWH-019); 
(7) 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole (Other name: 
JWH-200); 
(8) 1-Pentyl-3-(2-methoxyphenylacetyl)indole (Other name: JWH­
250); 
(9) 1-Pentyl-3-[1-(4-methoxynaphthoyl)]indole (Other name: JWH­
081); 
(10) 1-Pentyl-3-(4-methyl-1-naphthoyl)indole (Other name: JWH­
122); 
(11) 1-pentyl-3-(4-chloro-1-naphthoyl)indole (Other name: JWH­
398); 
(12) 1-(5-Fluoropentyl)-3-(1-naphthoyl)indole (Other name: 
AM2201); 
(13) 1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole (Other name: 
AM694); 
(14) 1-Pentyl-3-[(4-methoxy)-benzoyl]indole (Other names: SR-19, 
RCS-4); 
(15) 1-Cyclohexylethyl-3-(2-methoxyphenylacetyl)indole (Other 
names: SR-18;RCS-8); and 
(16) 1-Pentyl-3-(2-chlorophenylacetyl)indole (Other name: JWH- 
203). 
-Schedule I Temporarily Listed Substances Subject to Emergency 
Scheduling by the U.S. Drug Enforcement Administration 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the 
following substances or that contains any of the substance's isomers, esters, 
ethers, salts and salts of isomers, esters, and ethers if the existence of the 
salts, esters, ethers isomers, and salts of isomers, esters, ethers is possible 
within the specific chemical designation:  
(1) Fentanyl-related substances. 
(1-1) Fentanyl-related substance means any substance not 
otherwise listed under another Administration Controlled Substance Code 
Number, and for which no exemption or approval is in effect under Section 
505 of the Federal Food, Drug, and Cosmetic Act [21 U.S.C. 355], that is 
structurally related to fentanyl by one or more of the following modifications: 
(1-1-1) Replacement of the phenyl portion of the 
phenethyl group by any monocycle, whether or not further substituted in or 
on the monocycle, 

 
                   
                    
 
                   
                    
 
 
 
 
 
       (1-1-2) Substitution in or on the phenethyl group with 
alkyl, alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino or nitro groups, 
      (1-1-3) Substitution in or on the piperidine ring with alkyl, 
alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, amino or nitro 
groups,
       (1-1-4) Replacement of the aniline ring with any aromatic 
monocycle whether or not further substituted in or on the aromatic 
monocycle, and/or 
(1-1-5) Replacement of the N-propionyl group by another 
acyl group. 
(1–2) This definition includes, but is not limited to, the following 
substances: 
(1-2-1) N-(1-(2-Fluorophenethyl)piperidin-4- 
yl)-N-(2-fluorophenyl)propionamide (Other name: 2′-fluoro-o­
fluorofentanyl); 
(1-2-2) N-(2-Methylphenyl)-N-(1-
phenethylpiperidin-4-yl)acetamide (Other name:o-methyl acetylfentanyl); 
(1-2-3) N-(1-Phenethylpiperidin-4-yl)-N,3­
diphenylpropanamide (Other names: β′-phenyl fentanyl; hydrocinnamoyl 
fentanyl); and, 
(1-2-4) N-(1-Phenethylpiperidin-4-yl)-N-phenylthiophene­
2-carboxamide (Other name: thiofuranyl fentanyl).  
(2) 4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2­
f][1,2,4]triazolo[4,3-α][1,4]diazepine (Other name: etizolam); 
 
(3) 8-chloro-6-(2-fluorophenyl)-1-methyl-4H­
benzo[f][1,2,4]triazolo[4,3-α][1,4]diazepine (Other name: flualprazolam); 
 
(4) 6-(2-chlorophenyl)-1-methyl-8-nitro-4H­
benzo[f][1,2,4]triazolo[4,3-α][1,4]diazepine (Other name: clonazolam); 
 
(5) 8-bromo-6-(2-fluorophenyl)-1-methyl-4H­
benzo[f][1,2,4]triazolo[4,3-α][1,4]diazepine (Other names: 8-bromo-6-(2­
fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-α][1,4]benzodiazepine and 
flubromazolam); 
 
(6) 7-chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H­
benzo[e][1,4]diazepin-2-one (Other name: diclazepam); 
 
(7) Methyl 3,3-dimethyl-2-(1-(pent-4-en-1-yl)-1H-indazole-3­
carboxamido)butanoate (Other name: MDMB–4en–PINACA); 
(8) Methyl 2-[[1-(4-fluorobutyl)indole-3-carbonyl]amino]-3,3­
dimethyl-butanoate (Other names: 4F–MDMB–BUTICA; 4F–MDMB–BICA); 
(9) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(pent-4-en-1-yl)-1H­
indazole-3-carboxamide (Other name: ADB–4en–PINACA); 
 
(10) 5-Pentyl-2-(2-phenylpropan-2-yl)pyrido[4,3-b]indol-1-one (Other 
names: CUMYL–PEGACLONE; SGT–151); 
 
(11) Ethyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3­
dimethyl-butanoate (Other names: 5F–EDMB–PICA; 5F–EDMB–2201); 
 
(12) Methyl 2-(1-(4-fluorobenzyl)-1H-indole-3-carboxamido)-3-methyl 
butanoate (Other name: MMB–FUBICA); 
*(13) N-ethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H-benzimidazol-1­
yl)ethan-1-amine (Other name: N-desethyl isotonitazene); and 
 
*(14) 2-(4-ethoxybenzyl)-5-nitro-1-(2-(piperidin-1-yl)ethyl)-1H­
benzimidazole (Other names: N-piperidinyl etonitazene; etonitazepipne). 

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
SCHEDULE II 
Schedule II consists of: 
-Schedule II Substances, Vegetable Origin or Chemical Synthesis 
The following substances, however produced, except those narcotic drugs 
listed in other schedules: 
(1) Opium and opiate, and a salt, compound, derivative, or 
preparation of opium or opiate, other than thebaine-derived butorphanol, 
naldemedine, nalmefene, naloxegol, naloxone, 6β-naltrexol, naltrexone, and 
samidorphan and their respective salts, but including: 
(1-1) Codeine (Other names: Morphine methyl ester; methyl 
morphine); 
(1–2) Dihydroetorphine (Other name: DHE); 
(1–3) Ethylmorphine (Other name: Dionin); 
(1–4) Etorphine hydrochloride (Other names: Etorphine HCl; 
M99); 
(1-5) Granulated opium; 
(1-6) Hydrocodone (Other name: dihydrocodeinone); 
(1–7) Hydromorphone (Other names: Dilaudid; 
dihydromophinone); 
(1–8) Metopon; 
(1-9) Morphine (Other names: MS Contin; Roxanol; Oramorph; 
RMS; MSIR); 
 
(1-10) Noroxymorphone; 
(1-11) Opium extracts; 
(1-12) Opium fluid extracts;
 
(1-13) Oripavine; 
(1-14) Oxycodone (Other names: OxyContin; Percocet; Endocet; 
Roxicodone; Roxicet); 
(1-15) Oxymorphone (Other name: Numorphan); 
(1-16) Powdered opium; 
(1-17) Raw opium (Other name: gum opium); 
(1-18) Thebaine; and 
(1-19) Tincture of opium (Other name: Laudanum). 
(2) A salt, compound, isomer, derivative, or preparation of a 
substance that is chemically equivalent or identical to a substance described 
by paragraph (1) of Schedule II substances, vegetable origin or chemical 
synthesis, other than the isoquinoline alkaloids of opium; 
(3) Opium poppy and poppy straw; 
(4) Cocaine, including: 
(4-1) its salts, its optical, positional, and geometric isomers, and 
the salts of those isomers;  
(4-2) Coca leaves and any salt, compound, derivative, or 
preparation of coca leaves and ecgonine and their salts, isomers, derivatives 
and salts of isomers and derivatives and any salt, compound derivative or 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
preparation thereof which is chemically equivalent or identical to a substance 
described by this paragraph, except that the substances shall not include:
 
 
 
(4-2-1) Decocainized coca leaves or extractions of coca 
leaves which extractions do not contain cocaine or ecgonine; or  
 
 
 
(4-2-2) Ioflupane. 
(5) Concentrate of poppy straw, meaning the crude extract of poppy 
straw in liquid, solid, or powder form that contains the phenanthrene 
alkaloids of the opium poppy. 
-Schedule II Opiates   
The following opiates, including their isomers, esters, ethers, salts, and salts 
of isomers, if the existence of these isomers, esters, ethers, and salts is 
possible within the specific chemical designation: 
(1) Alfentanil (Other name: Alfenta); 
(2) Alphaprodine (Other name: Nisentil); 
(3) Anileridine (Other name: Leritine); 
(4) Bezitramide (Other name: Burgodin); 
(5) Carfentanil (Other name: Wildnil); 
(6) Dextropropoxyphene, bulk (nondosage form) (Other name: 
Propoxyphene); 
(7) Dihydrocodeine (Other names: Didrate; Parzone); 
(8) Diphenoxylate; 
(9) Fentanyl (Other names: Duragesic; Oralet; Actiq; Sublimaze; 
Innovar); 
(10) Isomethadone (Other name: Isoamidone); 
(11) Levo-alphacetylmethadol (Other names: levo-α-acetylmethadol; 
levomethadyl acetate, LAAM); 
(12) Levomethorphan; 
(13) Levorphanol; 
(14) Metazocine; 
(15) Methadone (Other names: Dolophine; Methadose; Amidone); 
(16) Methadone Intermediate (Other name: 4-cyano-2­
dimethylamino-4,4-diphenyl butane); 
(17) Moramide Intermediate (Other name: 2-methyl-3-morpholino­
1,1-diphenylpropane-carboxylic acid);  
(18) Oliceridine (Other name: N-[(3-methoxythiophen-2-yl)methyl] 
({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro [4.5]decan-9-yl]ethyl})amine 
fumarate); 
(19) Pethidine (meperidine); 
(20) Pethidine Intermediate-A (Other name: 4-cyano-1-methyl-4­
phenylpiperidine); 
(21) Pethidine Intermediate-B (Other name: ethyl-4-phenylpiperidine­
4-carboxylate); 
(22) Pethidine Intermediate-C (Other name: 1-methyl-4­
phenylpiperidine-4-carboxylic acid); 
(23) Phenazocine (Other names: Narphen; Prinadol); 
(24) Piminodine;
 
(25) Racemethorphan; 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(26) Racemorphan (Other name: Dromoran); 
(27) Remifentanil (Other name: Ultiva); 
(28) Sufentanil (Other name: Sufenta; 
(29) Tapentadol; and 
(30) Thiafentanil (Other name: methyl 4-(2-methoxy-N­
phenylacetamido)-1-(2-(thiophen-2-yl)ethyl)piperidine-4-carboxylate). 
-Schedule II Stimulants 
Unless listed in another schedule and except as provided by the Texas 
Controlled Substances Act, Health and Safety Code, Section 481.033, a 
material, compound, mixture, or preparation that contains any quantity of 
the following substances having a potential for abuse associated with a 
stimulant effect on the central nervous system: 
(1) Amphetamine, its salts, optical isomers, and salts of its optical 
isomers; 
(2) Methamphetamine, including its salts, optical isomers, and salts of 
optical isomers; 
(3) Methylphenidate and its salts; 
(4) Phenmetrazine and its salts; and 
(5) Lisdexamfetamine, including its salts, isomers, and salts of its 
isomers. 
-Schedule II Depressants 
Unless listed in another schedule, a material, compound, mixture, or 
preparation that contains any quantity of the following substances having a 
depressant effect on the central nervous system, including the substance's 
salts, isomers, and salts of isomers if the existence of the salts, isomers, and 
salts of isomers is possible within the specific chemical designation: 
(1) Amobarbital; 
(2) Glutethimide; 
(3) Pentobarbital; and 
(4) Secobarbital. 
-Schedule II Hallucinogenic Substances 
(1) Nabilone (Other name: (±)-trans-3-(1,1-dimethylheptyl)-6,6a,7,8, 
10,10a-hexahydro-1-hydroxy-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one); 
and 
(2) Dronabinol in oral solution in drug products approved for 
marketing by the U.S. Food and Drug Administration. 
-Schedule II Precursors 
Unless specifically excepted or listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the 
following substances: 

 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
(1) Immediate precursor to methamphetamine: 
(1-1) Phenylacetone and methylamine if possessed together with 
intent to manufacture methamphetamine; 
(2) Immediate precursor to amphetamine and methamphetamine: 
 
 
(2-1) Phenylacetone (Other names: phenyl-2-propanone; P2P; 
benzyl methyl ketone; methyl benzyl ketone); 
(3) Immediate precursors to phencyclidine (PCP): 
 
 
(3-1) 1-phenylcyclohexylamine; 
(3-2) 1-piperidinocyclohexanecarbonitrile (PCC); and 
(4) Immediate precursor to fentanyl: 
 
 
(4-1) 4-anilino-N-phenethylpiperidine (ANPP). 
SCHEDULE III 
Schedule III consists of: 
-Schedule III Depressants  
Unless listed in another schedule and except as provided by the Texas 
Controlled Substances Act, Health and Safety Code, Section 481.033, a 
material, compound, mixture, or preparation that contains any quantity of 
the following substances having a potential for abuse associated with a 
depressant effect on the central nervous system: 
(1) A compound, mixture, or preparation containing amobarbital, 
secobarbital, pentobarbital, or any of their salts and one or more active 
medicinal ingredients that are not listed in a schedule; 
(2) A suppository dosage form containing amobarbital, secobarbital, 
pentobarbital, or any of their salts and approved by the U.S. Food and Drug 
Administration for marketing only as a suppository; 
(3) A substance that contains any quantity of a derivative of barbituric 
acid, or any salt of a derivative of barbituric acid, except those substances 
that are specifically listed in other schedules; 
(4) Chlorhexadol; 
(5) Any drug product containing gamma hydroxybutyric acid, including 
its salts, isomers, and salts of isomers, for which an application is approved 
under Section 505 of the Federal Food Drug and Cosmetic Act. 
(6) Ketamine, its salts, isomers, and salts of isomers. Some other 
names for ketamine: (±)-2-(2-chlorophenyl)-2-(methylamino)­
cyclohexanone;  
(7) Lysergic acid; 
(8) Lysergic acid amide; 
(9) Methyprylon; 
(10) Perampanel, and its salts, isomers, and salts of isomers;  
(11) Sulfondiethylmethane; 
(12) Sulfonethylmethane; 
(13) Sulfonmethane; and, 
(14) Tiletamine and zolazepam or any salt thereof (Other name for a 
tiletamine zolazepam combination product: Telazol. Other name for 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
tiletamine: 2-(ethylamino)-2-(2-thienyl) cyclohexanone. Other name for 
zolazepam: 4-(2-fluorophenyl)-6,8-dihydro-1,3,8 trimethyl-pyrazolo[3,4­
e][1,4] diazepin-7(1H)-one, flupyrazapon.) 
-Schedule III 
(1) Nalorphine. 
-Schedule III Narcotics 
Unless specifically excepted or unless listed in another schedule:  
(1) A material, compound, mixture, or preparation containing limited 
quantities of any of the following narcotic drugs, or any of their salts: 
(1-1) not more than 1.8 grams of codeine, or any of its salts, per 
100 milliliters or not more than 90 milligrams per dosage unit, with an 
equal or greater quantity of an isoquinoline alkaloid of opium; 
(1–2) not more than 1.8 grams of codeine, or any of its salts, per 
100 milliliters or not more than 90 milligrams per dosage unit, with 
one or more active, nonnarcotic ingredients in recognized therapeutic 
amounts; 
(1–3) not more than 1.8 grams of dihydrocodeine, or any of its 
salts, per 100 milliliters or not more than 90 milligrams per dosage unit, 
with one or more active, nonnarcotic ingredients in recognized therapeutic 
amounts; 
(1–4) not more than 300 milligrams of ethylmorphine, or any of 
its salts, per 100 milliliters or not more than 15 milligrams per dosage 
unit, with one or more active, non-narcotic ingredients in recognized 
therapeutic amounts; 
(1-5) not more than 500 milligrams of opium per 100 milliliters 
or per 100 grams, or not more than 25 milligrams per dosage unit, 
with one or more active, nonnarcotic ingredients in recognized 
therapeutic amounts; 
(1-6) not more than 50 milligrams of morphine, or any of its 
salts, per 100 milliliters or per 100 grams with one or more active, 
nonnarcotic ingredients in recognized therapeutic amounts; and  
(2) any material, compound, mixture, or preparation containing any of 
the following narcotic drugs or their salts: 
 
 
(2-1) Buprenorphine. 
-Schedule III Stimulants 
Unless listed in another schedule, a material, compound, mixture, or 
preparation that contains any quantity of the following substances having a 
stimulant effect on the central nervous system, including the substance's 
salts, optical, positional, or geometric isomers, and salts of the substance's 
isomers, if the existence of the salts, isomers, and salts of isomers is 
possible within the specific chemical designation: 
(1) Benzphetamine; 

 
 
 
 
 
 
 
 
  
 
(2) Chlorphentermine; 
(3) Clortermine; and 
(4) Phendimetrazine. 
-Schedule III Anabolic Steroids and Hormones 
Anabolic steroids. Unless specifically excepted or unless listed in another 
schedule, any substance meeting the definition of anabolic steroid as set 
forth in 21 CFR Section 1300.01, including any material, compound, mixture, 
or preparation containing any quantity of the following substances, including 
its salts, esters and ethers: 
(1) 5α-androstan-3,17-dione; 
(2) 5α-androstan-3,6,17-trione; 
(3) 1-androstenediol (3β,17β-dihydroxy-5α-androst-1-ene); 
(4) 1-androstenediol (3α,17β-dihydroxy-5α-androst-1-ene); 
(5) 4-androstenediol (3β,17β-dihydroxy-androst-4-ene);  
(6) 5-androstenediol (3β,17β-dihydroxy-androst-5-ene);  
(7) 1-androstenedione (5α-androst-1-en-3,17-dione); 
(8) 4-androstenedione (androst-4-en-3,17-dione); 
(9) 5-androstenedione (androst-5-en-3,17-dione); 
(10) bolasterone (7α,17α-dimethyl-17β-hydroxyandrost-4-en-3-one);  
(11) boldenone (17β-hydroxyandrost-1,4-diene-3-one);  
(12) boldione (androsta-1,4-diene-3,17-dione); 
(13) 6-bromo-androsta-1,4-diene-3,17-dione; 
(14) 6-bromo-androstan-3,17-dione; 
(15) calusterone (7β,17α-dimethyl-17β-hydroxyandrost-4-en-3-one);  
(16) 4-chloro-17α-methyl-androsta-1,4-diene-3,17β-diol; 
(17) 4-chloro-17α-methyl-androst-4-ene-3β,17β-diol; 
(18) 4-chloro-17α-methyl-17β-hydroxy-androst-4-en-3-one;  
(19) 4-chloro-17α-methyl-17β-hydroxy-androst-4-ene-3,11-dione;  
(20) clostebol (4-chloro-17β-hydroxyandrost-4-en-3-one);  
(21) dehydrochloromethyltestosterone (4-chloro-17β-hydroxy-17α-methyl­
androst-1,4-dien-3-one); 
(22) desoxymethyltestosterone (17α-methyl-5α-androst-2-en-17β-ol) (Other 
name: madol); 
(23) 4-dihydrotestosterone (17β-hydroxy-androstan-3-one); 
(24) Δ1-dihydrotestosterone (17β-hydroxy-5α-androst-1-en-3-one) (Other 
name: 1-testosterone); 
(25) 3β,17β-dihydroxy-5α-androstane; 
(26) 3α,17β-dihydroxy-5α-androstane; 
(27) 2α,17α-dimethyl-17β-hydroxy-5β-androstan-3-one; 
(28) drostanolone (17β-hydroxy-2α-methyl-5α-androstan-3-one); 
(29) 2α,3α-epithio-17α-methyl-5α-androstan-17β-ol; 
(30) estra-4,9,11-triene-3,17-dione;  

 
(31) 13β-ethyl-17β-hydroxygon-4-en-3-one; 
(32) ethylestrenol (17α-ethyl-17β-hydroxyestr-4-ene);  
(33) fluoxymesterone (9-fluoro-17α-methyl-11β,17β-dihydroxyandrost-4­
en-3-one); 
(34) formebolone (2-formyl-17α-methyl-11α,17β-dihydroxyandrost-1,4­
dien-3-one); 
(35) furazabol (17α-methyl-17β-hydroxyandrostano[2,3-c]furazan);  
(36) [3,2-c]furazan-5α-androstan-17β-ol; 
(37) 18a-homo-3-hydroxy-estra-2,5(10)-dien-17-one; 
(38) 4-hydroxy-19-nortestosterone (4,17β-dihydroxy-estr-4-en-3-one);  
(39) 4-hydroxy-androst-4-ene-3,17-dione;  
(40) 17β-hydroxy-androstano[2,3-d]isoxazole; 
(41) 17β-hydroxy-androstano[3,2-c]isoxazole; 
(42) 3β-hydroxy-estra-4,9,11-trien-17-one; 
(43) 4-hydroxytestosterone (4,17β-dihydroxy-androst-4-en-3-one);  
(44) mestanolone (17α-methyl-17β-hydroxy-5α-androstan-3-one); 
(45) mesterolone (1α-methyl-17β-hydroxy-5α-androstan-3-one); 
(46) methandienone (17α-methyl-17β-hydroxyandrost-1,4-dien-3-one);  
(47) methandriol (17α-methyl-3β,17β-dihydroxyandrost-5-ene); 
(48) methasterone (2α,17α-dimethyl-5α-androstan-17β-ol-3-one or 2α,17α­
dimethyl-17β-hydroxy-5α-androstan-3-one); 
(49) methenolone (1-methyl-17β-hydroxy-5α-androst-1-en-3-one); 
(50) 17α-methyl-androsta-1,4-diene-3,17β-diol; 
(51) 17α-methyl-5α-androstan-17β-ol; 
(52) 17α-methyl-androstan-3-hydroxyimine-17β-ol; 
(53) 6α-methyl-androst-4-ene-3,17-dione; 
(54) 17α-methyl-androst-2-ene-3,17β-diol; 
(55) 17α-methyl-3β,17β-dihydroxy-5α-androstane; 
(56) 17α-methyl-3α,17β-dihydroxy-5α-androstane; 
(57) 17α-methyl-3β,17β-dihydroxyandrost-4-ene; 
(58) 17α-methyl-4-hydroxynandrolone (17α-methyl-4-hydroxy-17β­
hydroxyestr-4-en-3-one); 
(59) methyldienolone (17α-methyl-17β-hydroxyestra-4,9(10)-dien-3-one);  
(60) 17α-methyl-Δ1-dihydrotestosterone (17β-hydroxy-17α-methyl-5α­
androst-1-en-3-one) (Other name: 17-α-methyl-1-testosterone); 
(61) methyltestosterone (17α-methyl-17β-hydroxyandrost-4-en-3-one); 
(62) methyltrienolone (17α-methyl-17β-hydroxyestra-4,9,11-trien-3-one);  
(63) mibolerone (7α,17α-dimethyl-17β-hydroxyestr-4-en-3-one);  
(64) nandrolone (17β-hydroxyestr-4-en-3-one);  
(65) 19-nor-4-androstenediol (3β,17β-dihydroxyestr-4-ene); 
(66) 19-nor-4-androstenediol (3α,17β-dihydroxyestr-4-ene); 
(67) 19-nor-5-androstenediol (3β,17β-dihydroxyestr-5-ene); 
(68) 19-nor-5-androstenediol (3α,17β-dihydroxyestr-5-ene); 

 
  
 
 
 
 
  
 
 
 
 
 
(69) 19-nor-4,9(10)-androstadienedione (estra-4,9(10)-diene-3,17-dione); 
(70) 19-nor-4-androstenedione (estr-4-en-3,17-dione); 
(71) 19-nor-5-androstenedione (estr-5-en-3,17-dione); 
(72) norbolethone (13β,17α-diethyl-17β-hydroxygon-4-en-3-one); 
(73) norclostebol (4-chloro-17β-hydroxyestr-4-en-3-one);  
(74) norethandrolone (17α-ethyl-17β-hydroxyestr-4-en-3-one);  
(75) normethandrolone (17α-methyl-17β-hydroxyestr-4-en-3-one);  
(76) oxandrolone (17α-methyl-17β-hydroxy-2-oxa-5α-androstan-3-one); 
(77) oxymesterone (17α-methyl-4,17β-dihydroxyandrost-4-en-3-one);  
(78) oxymetholone (17α-methyl-2-hydroxymethylene-17β-hydroxy-5α­
androstan-3-one); 
(79) prostanozol (17β-hydroxy-5α-androstano[3,2-c]pyrazole or [3,2­
c]pyrazole-5α-androstan-17β-ol); 
(80) [3,2-c]pyrazole-androst-4-en-17β-ol; 
(81) stanozolol (17α-methyl-17β-hydroxy-5α-androst-2-eno[3,2-c]­
pyrazole); 
(82) stenbolone (17β-hydroxy-2-methyl-5α-androst-1-en-3-one); 
(83) testolactone (13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic 
acid lactone); 
(84) testosterone (17β-hydroxyandrost-4-en-3-one); 
(85) tetrahydrogestrinone (13β,17α-diethyl-17β-hydroxygon-4,9,11-trien-3­
one); and 
(86) trenbolone (17β-hydroxyestr-4,9,11-trien-3-one). 
-Schedule III Hallucinogenic Substances 
(1) Dronabinol (synthetic) in sesame oil and encapsulated in a soft 
gelatin capsule in U.S. Food and Drug Administration approved drug product. 
(Some other names for dronabinol: 
(6aR-trans)-6a,7,8,10a-tetrahydro-6,6,9-tri­
methyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol; (-)-∆-9­
(trans)-tetrahydrocannabinol). 
SCHEDULE IV 
Schedule IV consists of: 
-Schedule IV Depressants  
Except as provided by the Texas Controlled Substances Act, Health and 
Safety Code, Section 481.033, a material, compound, mixture, or 
preparation that contains any quantity of the following substances or any of 
the substance's salts, isomers, and salts of isomers if the existence of the 
salts, isomers, and salts of isomers is possible within the specific chemical 
designation having a potential for abuse associated with a depressant effect 
on the central nervous system: 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(1) Alfaxalone (5α-pregnan-3α-ol-11,20-dione); 
(2) Alprazolam; 
(3) Barbital; 
(4) Brexanolone (3α-hydroxy-5α-pregnan-20-one) (Other name: 
allopregnanolone); 
(5) Bromazepam; 
(6) Camazepam;   
(7) Chloral betaine; 
(8) Chloral hydrate; 
(9) Chlordiazepoxide; 
(10) Clobazam; 
(11) Clonazepam; 
(12) Clorazepate; 
(13) Clotiazepam; 
(14) Cloxazolam; 
(15) Daridorexant; 
(16) Delorazepam; 
(17) Diazepam; 
(18) Dichloralphenazone; 
(19) Estazolam; 
(20) Ethchlorvynol;
 
(21) Ethinamate; 
(22) Ethyl loflazepate; 
(23) Fludiazepam; 
(24) Flunitrazepam; 
(25) Flurazepam; 
(26) Fospropofol;
 
(27) Halazepam; 
(28) Haloxazolam; 
(29) Ketazolam; 
(30) Lemborexant; 
(31) Loprazolam; 
(32) Lorazepam; 
(33) Lormetazepam; 
(34) Mebutamate;
 
(35) Medazepam;
 
(36) Meprobamate; 
(37) Methohexital; 
(38) Methylphenobarbital (Other name: mephobarbital);
 
(39) Midazolam; 
(40) Nimetazepam; 
(41) Nitrazepam; 
(42) Nordiazepam;
 
(43) Oxazepam; 
(44) Oxazolam; 
(45) Paraldehyde; 
(46) Petrichloral; 
(47) Phenobarbital; 
(48) Pinazepam; 

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
                
 
 
  
 
(49) Prazepam; 
(50) Quazepam; 
(51) Remimazolam;
 
(52) Suvorexant; 
(53) Temazepam; 
(54) Tetrazepam; 
(55) Triazolam; 
(56) Zaleplon; 
(57) Zolpidem; 
(58) Zopiclone; and 
(59) Zuranolone. 
-Schedule IV Stimulants 
Unless listed in another schedule, a material, compound, mixture, or 
preparation that contains any quantity of the following substances having a 
stimulant effect on the central nervous system, including the substance's 
salts, optical, positional, or geometric isomers, and salts of those isomers if 
the existence of the salts, isomers, and salts of isomers is possible within the 
specific chemical designation: 
(1) Cathine [(+)-norpseudoephedrine]; 
(2) Diethylpropion; 
(3) Fencamfamin; 
(4) Fenproporex;
 
(5) Mazindol; 
(6) Mefenorex; 
(7) Modafinil; 
(8) Pemoline (including organometallic complexes and their chelates); 
(9) Phentermine; 
(10) Pipradrol; 
(11) Serdexmethylphenidate; 
(12) Sibutramine; 
(13) Solriamfetol ((R)-2-amino-3-phenylpropyl carbamate) (Other 
names: benzenepropanol; β-amino-carbamate (ester));  
and 
(14) SPA [1-dimethylamino-1,2-diphenylethane].  
-Schedule IV Narcotics 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation containing limited quantities of the 
following narcotic drugs or their salts: 
(1) Not more than 1 milligram of difenoxin and not less than 25 
micrograms of atropine sulfate per dosage unit; 
(2) Dextropropoxyphene 
(α-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane); and 
(3) 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol 
(Other name: tramadol). 

 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
  
 
 
 
 
 
 
 
 
 
-Schedule IV Other Substances 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, substance's salts: 
(1) Butorphanol, including its optical isomers;  
(2) Carisoprodol; 
(3) Eluxadoline (other name: 5-[[[(2S)-2-amino-3-[4­
(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H­
imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid) including its 
salts, isomers, and salts of isomers; 
(4) Lorcarserin including its salts, isomers and salts of isomers, 
whenever the existence of such salts, isomers, and salts of isomers is 
possible; and 
(5) Pentazocine, its salts, derivatives, compounds, or mixtures. 
SCHEDULE V 
Schedule V consists of: 
-Schedule V Narcotics Containing Nonnarcotic Active Medicinal 
Ingredients 
A compound, mixture, or preparation containing limited quantities of any of 
the following narcotic drugs that also contain one or more nonnarcotic active 
medicinal ingredients in sufficient proportion to confer on the compound, 
mixture, or preparation valuable medicinal qualities other than those 
possessed by the narcotic drug alone: 
(1) Not more than 200 milligrams of codeine, or any of its salts, per 
100 milliliters or per 100 grams; 
(2) Not more than 100 milligrams of dihydrocodeine, or any of its 
salts, per 100 milliliters or per 100 grams; 
(3) Not more than 100 milligrams of ethylmorphine, or any of its salts, 
per 100 milliliters or per 100 grams; 
(4) Not more than 2.5 milligrams of diphenoxylate and not less than 
25 micrograms of atropine sulfate per dosage unit; 
(5) Not more than 15 milligrams of opium per 29.5729 milliliters or per 
28.35 grams; and 
(6) Not more than 0.5 milligram of difenoxin and not less than 25 
micrograms of atropine sulfate per dosage unit. 
-Schedule V Stimulants 
Unless specifically exempted or excluded or unless listed in another 
schedule, a compound, mixture, or preparation which contains any quantity 
of the following substances having a stimulant effect on the central nervous 
system, including its salts, isomers, and salts of isomers: 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(1) Pyrovalerone. 
-Schedule V Depressants 
Unless specifically exempted or excluded or unless listed in another 
schedule, any material, compound, mixture, or preparation, which contains 
any quantity of the following substances having a depressant effect on the 
central nervous system, including its salts, isomers, and salts of isomers, 
unless specifically excepted, if the existence of these salts, isomers, and 
salts of isomers is possible within the specific chemical designation: 
(1) Brivaracetam ((2S)-2-[(4R)-2-oxo-4-propylpyrrolidin-1­
yl]butanamide) (Other names; BRV; UCB-34714; Briviact); 
(2) Cenobamate [(1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl] 
carbamate; 
(3) Ezogabine including its salts, isomers and salts of isomers, 
whenever the existence of such salts, isomers and salts of isomers is 
possible; 
(4) Ganaxolone (3α-hydroxy-3β-methyl-5α-pregnan-20-one); 
(5) Lacosamide [(R)-2-acetoamido-N-benzyl-3-methoxy­
proprionamide]; 
(6) Lasmiditan [2,4,6-trifluoro-N-(6-(1-methylpiperidine-4­
carbonyl)pyridine-2-yl)benzamide]; and, 
(7) Pregabalin [(S)-3-(aminomethyl)-5-methylhexanoic acid].

Instrument

Order Placing Dipentylone in Schedule I, Temporarily Placing N-Pyrrolidino Metonitazene, N-Pyrrolidino Protonitazene, and Seven Benzimidazole-Opioids in Schedule I, and Permanently Placing Seven Specific Fentanyl-Related Substances in Schedule I

Source

https://www.sos.state.tx.us/texreg/archive/March132026/In%20Addition/202601019-1.pdf

Retrieved

2026-11-02

Fingerprint

15e984f1f3c381f7

I. The U.S. Drug Enforcement Administration (DEA) issued a final rule creating a 
specific listing for 1-(1,3-benzodioxol-5-yl)-2-(dimethylamino)pentan-1-one (other 
names: dipentylone, N,N-dimethylpentylone), including their isomers, esters, 
ethers, salts, and salts of isomers, esters, and ethers whenever the existence of 
such isomers, esters, ethers, and salts is possible within the specific chemical 
designation, in schedule I of the Controlled Substances Act (CSA) effective August 
8, 2025. This final rule was published in the Federal Register, Volume 90, Number 
151, pages 38396-38398. 
Dipentylone is already a controlled substance in the United States under schedule I, 
as it is a positional isomer of the schedule I hallucinogen N-ethylpentylone. This 
scheduling action creates a specific listing for dipentylone. 
II. The DEA issued a temporary order placing 
2-(4-methoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole 
(commonly known as, N-pyrrolidinometonitazene or metonitazepyne) and 5-nitro­
2-(4-propoxybenzyl)-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole (commonly 
known as, N-pyrrolidino protonitazene or protonitazepyne), including their isomers, 
esters, ethers, salts, and salts of isomers, esters, and ethers whenever the 
existence of such isomers, esters, ethers, and salts is possible, in schedule I of the 
CSA effective August 15, 2025. This final rule was published in the Federal Register, 
Volume 90, Number 156, pages 39314-39319. 
This scheduling action was taken to avoid an imminent hazard to public safety and 
pursuant to N-pyrrolidino metonitazene and N-pyrrolidino protonitazene having: 
 
a high potential for abuse; 
 
no currently accepted medical use in treatment in the United States; and 
 
a lack of accepted safety for use under medical supervision. 
III. The DEA issued a temporary order extending the temporary schedule I status of 
seven specific fentanyl-related substances effective December 31, 2024. This 
temporary scheduling order was published in the Federal Register, Volume 89, 
Number 249, pages 106311-106315. The order extends the temporary scheduling 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
of the following seven controlled substances in schedule I of the CSA, including 
their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers 
whenever the existence of such isomers, esters, ethers, and salts is possible within 
the specific chemical designation: 
 
beta-methylacetyl fentanyl (N-phenyl-N-(1-(2-phenylpropyl)piperidin-4­
yl)acetamide), 
 
meta-fluorofuranyl fentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide), 
 
ortho-chlorofentanyl (N-(2-chlorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide), 
 
ortho-methylcyclopropyl fentanyl(N-(2-methylphenyl)-N-(1­
phenethylpiperidin-4-yl)cyclopropanecarboxamide), 
 
para-chlorofentanyl (N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide), 
 
para-fluoro valeryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)pentanamide), and 
 
tetrahydrothiofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenyltetrahydrothiophene-2-carboxamide; other name: 
tetrahydrothiophene fentanyl). 
The DEA issued a final rule permanently placing these seven specific fentanyl­
related substances, including their isomers, esters, ethers, salts, and salts of 
isomers, esters, and ethers, in schedule I of the CSA effective September 18, 2025. 
This final rule was published in the Federal Register, Volume 90, Number 179, 
pages 44979-44984. 
This scheduling action was taken pursuant to beta-methylacetyl fentanyl, meta­
fluorofuranyl fentanyl, ortho-chlorofentanyl, ortho-methylcyclopropyl fentanyl, 
para-chlorofentanyl, para-fluoro valeryl fentanyl, and tetrahydrothiofuranyl fentanyl 
having: 
 
a high potential for abuse due to their analgesic effects that are mediated by 
mu-opioid receptor agonism; 
 
no currently accepted medical use in treatment in the United States; and 
 
a lack of accepted safety for use under medical supervision. 
IV. The DEA issued a temporary order extending the temporary schedule I status of 
five designer benzodiazepines effective July 26, 2025. This temporary scheduling 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
order was published in the Federal Register, Volume 90, Number 141, pages 
35236-35238. The order extends the temporary scheduling of the following five 
controlled substances in schedule I of the CSA, including their isomers, esters, 
ethers, salts, and salts of isomers, esters, and ethers whenever the existence of 
such isomers, esters, ethers, and salts is possible within the specific chemical 
designation: 
 
clonazolam (6-(2-chlorophenyl)-1-methyl-8-nitro-4H­
benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine); 
 
diclazepam (7-chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H­
benzo[e][1,4]diazepin-2-one); 
 
etizolam (4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2­
f][1,2,4]triazolo[4,3-a][1,4]diazepine); 
 
flualprazolam (8-chloro-6-(2-fluorophenyl)-1-methyl-4H­
benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine); and 
 
flubromazolam (8-bromo-6-(2-fluorophenyl)-1-methyl-4H­
benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine). 
V. The DEA issued a temporary order placing seven benzimidazole-opioids, including 
their isomers, esters ethers, salts, and salts of isomers, esters, and ethers 
whenever the existence of such isomers, esters, ethers, and salts is possible, as 
identified below, in schedules I of the CSA, effective October 15, 2025. This 
temporary scheduling order was published in the Federal Register, Volume 90, 
Number 179, pages 48259-48266. 
 
2-(2-((2,3-dihydrobenzofuran-5-yl)methyl)-5-nitro-1H-benzimidazol-1-yl)­
N,N-diethylethan-1-amine (other name: ethyleneoxynitazene); 
 
2-(2-(benzodioxol-5-ylmethyl)-5-nitro-1H-benzimidazol-1-yl)-N,N­
diethylethan-1-amine (other names: methylenedioxynitazene; 3′,4′­
methylenedioxynitazene); 
 
2-(2-(4-ethoxybenzyl)-5-methyl-1H-benzimidazol-1-yl)-N,N-diethylethan-1­
amine (other name: 5-methyl etodesnitazene); 
 
2-(2-(4-ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N-ethylethan-1-amine 
(other name: N-desethyl etonitazene); 
 
N-ethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1-amine 
(other name: N-desethyl protonitazene); 
 
2-(2-(4-ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N,N-dimethylethan-1­
amine (other name: N,N-dimethylamino etonitazene); and 
 
2-(4-isopropoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(other name: N-pyrrolidino isotonitazene). 
This scheduling action was taken to avoid an imminent hazard to the public safety 
and pursuant to ethyleneoxynitazene, methylenedioxynitazene, 5-methyl 
etodesnitazene, N-desethyl etonitazene, N-desethyl protonitazene, N,N­
dimethylamino etonitazene, and N-pyrrolidino isotonitazene having: 
 
A high potential for abuse; 
 
No currently accepted medical use in treatment in the United States; and 
 
a lack of accepted safety for use under medical supervision. 
Pursuant to the Texas Controlled Substances Act, Health and Safety Code Section 
481.034(g), at least thirty-one days have expired since notice of the above 
referenced actions were published in the Federal Register. In the capacity as 
Commissioner of the Texas Department of State Health Services, Jennifer Shuford, 
M.D., does hereby order that the substances dipentylone be placed in schedule I, 
N-pyrrolidino metonitazene, N-pyrrolidino protonitazene, and seven benzimidazole­
opioids be temporarily placed in Schedule I, and seven specific fentanyl-related 
substances be permanently placed in Schedule I. 
Note: Additions are marked by an asterisk (*). 
-Schedule I Opiates 
The following opiates, including their isomers, esters, ethers, salts, and salts of 
isomers, esters, and ethers, unless specifically excepted, if the existence of these 
isomers, esters, ethers, and salts are possible within the specific chemical 
designation: 
(1) Acetyl-α-methylfentanyl (N-[1-(1-methyl-2-phenethyl)-4-piperidinyl]-N­
phenylacetamide); 
(2) Acetylmethadol; 
(3) Acetyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide); 
(4) Acryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylacrylamide) (Other 
name: acryloylfentanyl); 
(5) AH-7921 (3,4-dichloro-N-[1-(dimethylamino) cyclohexymethyl]benzamide); 
(6) Allylprodine; 
(7) Alphacetylmethadol (except levo-α-cetylmethadol, levo-α-acetylmethadol, 
levomethadyl acetate, or LAAM); 
(8) α′-Methyl butyryl fentanyl (2-methyl-N-(1-phenethylpiperidin-4-yl)-N­
phenylbutanamide); 
(9) α-Methylfentanyl or any other derivative of fentanyl; 

 
 
 
 
 
 
 
 
 
 
(10) α-Methylthiofentanyl (N-[1-methyl-2-(2-thienyl)ethyl-4-piperidinyl] N­
phenylpropanamide); 
(11) Benzethidine; 
(12) β-Hydroxyfentanyl (N-[1-(2-hydroxy-2-phenethyl)-4-piperidinyl]-N­
phenylpropanamide); 
(13) β-Hydroxy-3-methylfentanyl (N-[1-(2-hydroxy-2-phenethyl)-3-methyl-4­
piperidinyl]-N-phenylpropanamide); 
(14) β-hydroxythiofentanyl (Other names: N-[1-[2-hydroxy-2-(thiophen-2­
yl)ethyl]piperidin-4-yl]-N-phenylproprionamide; N-[1-[2-hydroxy-2-(2­
thienyl)ethyl]-4-piperidnyl]-N-phenylpropanamide); 
(15) β-Methyl fentanyl (N-phenyl-N-(1-(2-phenylpropyl)piperidin-4­
yl)propionamide); 
*(16) β-Methylacetyl fentanyl (N-phenyl-N-(1-(2-phenylpropyl)piperidin-4­
yl)acetamide); 
(17) β′-Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N,3-diphenylpropanamide) 
(Other name: 3-phenylpropanoyl fentanyl); 
(18) Betaprodine; 
(19) Brorphine (1–(1–(1–(4-bromophenyl)ethyl)piperidin-4–yl)–1,3-dihydro-2H­
benzo[d]imidazol-2-one); 
(20) Butonitazene (2-(2-(4-butoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N,N­
diethylethan-1-amine); 
(21) Butyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbutanamide); 
(22) Clonitazene; 
(23) Crotonyl fentanyl (Other name: (E)-N-(1-Phenethylpiperidin-4-yl)-N­
phenylbut-2-enamide); 
(24) Cyclopentyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-
Phenylcyclopentanecarboxamide);  
(25) Cyclopropyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenylcyclopropanecarboxamide); 
(26) Diampromide; 
(27) Diethylthiambutene; 
(28) Difenoxin; 
(29) Dimenoxadol; 
(30) 2′,5′-Dimethoxyfentanyl (N-(1-(2,5-dimethoxyphenethyl)piperidin-4-yl)-N­
phenylpropionamide); 
(31) Dimethylthiambutene; 
(32) Dioxaphetyl butyrate; 
(33) Dipipanone; 
(34) Ethylmethylthiambutene; 
(35) 2-(2-(4-ethoxybenzyl)-1H-benzimidazol-1-yl)-N,N-diethylethan-1-amine 
(Other names: etodesnitazene; etazene); 
(36) Etonitazene; 
(37) Etoxeridine; 
(38) Fentanyl carbamate (ethyl (1-phenethylpiperidin-4-yl)(phenyl)carbamate); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
(39) Flunitazene (N,N-diethyl-2-(2-(4-fluorobenzyl)-5-nitro-1H-benzimidazol-1­
yl)ethan-1-amine); 
(40) 4-Fluoroisobutyryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)isobutyramide) (Other name: p-fluoroisobutyryl fentanyl); 
(41) 2′-Fluoro o-fluorofentanyl (N-(1-(2-fluorophenethyl)piperidin-4-yl)-N-(2­
fluorophenyl)propionamide) (Other name: 2′-fluoro 2-fluorofentanyl); 
(42) Furanyl fentanyl (N-(1-phenethylpiperdin-4-yl)-N-phenylfuran-2­
carboxamide); 
(43) 3-Furanyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylfuran-3­
carboxamide); 
(44) Furethidine; 
(45) Hydroxypethidine; 
(46) Isobutyryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide);  
(47) Isotonitazene (N,N-diethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H­
benzimidazol-1-yl)ethan-1-amine); 
(48) Isovaleryl fentanyl (3-methyl-N-(1-phenethylpiperidin-4-yl)-N­
phenylbutanamide); 
(49) Ketobemidone; 
(50) Levophenacylmorphan; 
(51) m-Fluorofentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide); 
*(52) m-Fluorofuranyl fentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide); 
(53) m-Fluoroisobutyryl fentanyl (N-(3-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)isobutyramide); 
(54) Meprodine; 
(55) Methadol; 
(56) Methoxyacetyl fentanyl (2-methoxy-N-(1-phenethylpiperidin-4-yl)-N­
phenylacetamide); 
(57) 2-Methyl AP-237 (1-(2-methyl-4-(3-phenylprop-2-en-1-yl)piperazin-1­
yl)butan-1-one); 
(58) 4′-Methyl acetyl fentanyl (N-(1-(4-methylphenethyl)piperidin-4-yl)-N­
phenylacetamide); 
(59) 3-Methylfentanyl (N-[3-methyl-1-(2-phenylethyl)-4-piperidyl]-N-
phenylpropanamide);  
(60) 3-Methylthiofentanyl (N-[3-methyl-1-(2-thienyl)ethyl-4-piperidinyl]-N­
phenylpropanamide); 
(61) Metodesnitazene (N,N-diethyl-2-(2-(4-methoxybenzyl)-1H-benzimidazol-1­
yl)ethan-1-amine); 
(62) Metonitazene (N,N-diethyl-2-(2-(4-methoxybenzyl)-5-nitro-1H-benzimidazol­
1-yl)ethan-1-amine); 
(63) Moramide; 
(64) Morpheridine; 
(65) MPPP (1-methyl-4-phenyl-4-propionoxypiperidine);  
(66) MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine); 

 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
(67) Noracymethadol; 
(68) Norlevorphanol; 
(69) Normethadone; 
(70) Norpipanone; 
(71) 2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzimidazole 
(other names: N-pyrrolidino etonitazene; etonitazepyne); 
(72) Ocfentanil (N-(2-fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4­
yl)acetamide); 
*(73) o-Chlorofentanyl (N-(2-chlorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide); 
(74) o-Fluoroacryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)acrylamide); 
(75) o-Fluorobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)butyramide) (Other name:2-fluorobutyryl fentanyl); 
(76) o-Fluorofentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide) (Other name: 2-fluorofentanyl); 
(77) o-Fluorofuranyl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide); 
(78) o-Fluoroisobutyryl fentanyl (N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)isobutyramide); 
(79) o-Methyl acetylfentanyl (N-(2-methylphenyl)-N-(1-phenethylpiperidin-4­
yl)acetamide) (Other name: 2-methyl acetylfentanyl); 
*(80) o-Methylcyclopropyl fentanyl (N-(2-methylphenyl)-N-(1-phenethylpiperidin-4­
yl)cyclopropanecarboxamide); 
(71) o-Methyl methoxyacetyl fentanyl (2-methoxy-N-(2-methylphenyl)-N-(1­
phenethylpiperidin-4-yl)acetamide) (Other name: 2-methyl methoxyacetyl 
fentanyl); 
(82) p-Chloroisobutyryl fentanyl (N-(4-chlorophenyl)-N-(1- phenethylpiperidin-4­
yl)isobutyramide); 
*(83) p-Chlorofentanyl (N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide); 
(84) p-Fluorobutyryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)butyramide); 
(85) p-Fluorofentanyl (N-(4-fluorophenyl)-N-[1-(2-phenethyl)-4 piperidinyl] 
propanamide); 
(86) p-Fluoro furanyl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide); 
*(87) p-Fluoro valeryl fentanyl (N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4­
yl)pentanamide); 
(88) p-Methoxybutyryl fentanyl (N-(4-methoxyphenyl)-N-(1- phenethylpiperidin-4­
yl)butyramide;  
(89) p-Methoxyfuranyl fentanyl (N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4­
yl)furan-2-carboxamide); 
(90) p-Methylcyclopropyl fentanyl (N-(4-methylphenyl)-N-(1-phenethylpiperidin-4­
yl)cyclopropanecarboxamide); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
(91) p-Methylfentanyl (N-(4-methylphenyl)-N-(1-phenethylpiperidin-4­
yl)propionamide) (Other name: 4-methylfentanyl); 
(92) PEPAP (1-(2-phenethyl)-4-phenyl-4-acetoxypiperidine); 
(93) Phenadoxone; 
(94) Phenampromide; 
(95) Phencyclidine; 
(96) Phenomorphan; 
(97) Phenoperidine; 
(98) Phenyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylbenzamide) (Other 
name: benzoyl fentanyl); 
(99) Piritramide; 
(100) Proheptazine; 
(101) Properidine; 
(102) Propiram; 
(103) N,N-diethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1­
amine (other name: protonitazene); 
(104) Tetrahydrofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenyltetrahydrofuran-2-carboxamide); 
*(105) Tetrahydrothiofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N­
phenyltetrahydrothiophene-2-carboxamide) (Other name: tetrahydrothiophene 
fentanyl); 
(106) Thiofentanyl (N-phenyl-N-[1-(2-thienyl)ethyl-4-piperidinyl]-propanamide); 
(107) Thiofuranyl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylthiophene-2­
carboxamide) (Other names: 2-thiofuranyl fentanyl; thiophene fentanyl); 
(108) Tilidine; 
(109) Trimeperidine; 
(110) U-47700 (3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N­
methylbenzamide); 
(111) Valeryl fentanyl (N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide); and, 
(112) Zipeprol (1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1­
phenylpropan-2-ol). 
-Schedule I Hallucinogenic Substances 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the following 
hallucinogenic substances or that contains any of the substance's salts, isomers, 
and salts of isomers if the existence of the salts, isomers, and salts of isomers is 
possible within the specific chemical designation (for the purposes of this Schedule I 
hallucinogenic substances section only, the term "isomer" includes optical, 
positional, and geometric isomers): 
(1) α-Ethyltryptamine (Other names: etryptamine; Monase; α-ethyl-1H­
indole-3-ethanamine; 3-(2-aminobutyl) indole; α-ET; AET); 

 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(2) 4-Bromo-2,5-dimethoxyamphetamine (Other names: 4-bromo­
2,5-dimethoxy-α-methylphenethylamine; 4-bromo-2,5-DMA); 
(3) 4-Bromo-2,5-dimethoxyphenethylamine (Other names: Nexus; 2C-B; 2­
(4-bromo-2,5-dimethoxyphenyl)-1-aminoethane; α-desmethyl DOB);  
(4) 2,5-Dimethoxyamphetamine (Other names: 2,5-dimethoxy-α­
methylphenethylamine; 2,5-DMA); 
(5) 2,5-Dimethoxy-4-ethylamphetamine (Other name: DOET); 
(6) 2,5-Dimethoxy-4-(n)-propylthiophenethylamine, its optical isomers, salts 
and salts of isomers (Other name: 2C-T-7); 
(7) 4-Methoxyamphetamine (Other names: 4-methoxy-α­
methylphenethylamine; paramethoxyamphetamine; PMA); 
(8) 5-Methoxy-3,4-methylenedioxyamphetamine (Other name: MMDA); 
(9) 4-Methyl-2,5-dimethoxyamphetamine (Other names: 
4-methyl-2,5-dimethoxy-α-methyl-phenethylamine; “DOM”;“STP”); 
(10) 3,4-Methylenedioxyamphetamine (Other names: MDA; Love Drug); 
(11) 3,4-Methylenedioxymethamphetamine (Other names: MDMA; MDM; 
Ecstasy; XTC); 
(12) 3,4-Methylenedioxy-N-ethylamphetamine (Other names: N-ethyl- α­
methyl-3,4(methylenedioxy)phenethylamine; N-ethyl MDA; MDE; MDEA); 
(13) N-Hydroxy-3,4-methylenedioxyamphetamine (Other name: N-hydroxy 
MDA); 
(14) 3,4,5-Trimethoxyamphetamine (Other name: TMA); 
(15) 5-Methoxy-N,N-dimethyltryptamine (Other names: 5-methoxy-3-[2­
(dimethylamino)ethyl]indole; 5-MeO-DMT); 
(16) α-Methyltryptamine (Other name: AMT); 
(17) Bufotenine (Other names: 3-β-Dimethylaminoethyl)-5- hydroxyindole; 
3-(2-dimethylaminoethyl)-5-indolol; N,N-dimethylserotonin; 5-hydroxy-N,N­
dimethyltryptamine; mappine); 
(18) Diethyltryptamine (Other names: N,N-Diethyltryptamine; DET); 
(19) Dimethyltryptamine (Other name: DMT); 
(20) 5-Methoxy-N,N-diisopropyltryptamine (Other name: 5-MeO-DIPT); 
(21) Ibogaine (Other names: 7-Ethyl-6,6-β-7,8,9,10,12,13-octhydro-2­
methoxy-6,9-methano-5H-pyrido[1′,2′:1,2] azepino [5,4-b] indole; Tabernanthe 
iboga); 
(22) Lysergic acid diethylamide; 
(23) Marihuana, the term marihuana does not include hemp, as defined in 
Title 5, Agriculture Code, Chapter 121; 
(24) Mescaline; 
(25) Parahexyl (Other names: 3-Hexyl-1-hydroxy-7,8,9,10-tetrahydro-6,6,9­
trimethyl-6H-dibenzo[b,d]pyran; Synhexyl); 
(26) Peyote, unless unharvested and growing in its natural state, meaning all 
parts of the plant classified botanically as Lophophora williamsii Lemaire, whether 
growing or not, the seeds of the plant, an extract from a part of the plant, and 
every compound, manufacture, salt, derivative, mixture, or preparation of the 
plant, its seeds, or extracts; 

 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
  
 
 
  
  
 
 
 
 
(27) N-ethyl-3-piperidyl benzilate; 
(28) N-methyl-3-piperidyl benzilate; 
(29) Psilocybin; 
(30) Psilocyn; 
(31) Tetrahydrocannabinols, meaning tetrahydrocannabinols naturally 
contained in a plant of the genus Cannabis (cannabis plant), except for 
tetrahydrocannabinols in hemp (as defined under Section 297A(1) of the 
Agricultural Marketing Act of 1946), as well as synthetic equivalents of the 
substances contained in the cannabis plant, or in the resinous extractives of such 
plant, and/or synthetic substances, derivatives, and their isomers with similar 
chemical structure and pharmacological activity to those substances contained in 
the plant, such as the following: 
1 cis or trans tetrahydrocannabinol, and their optical isomers; 
6 cis or trans tetrahydrocannabinol, and their optical isomers; 
3,4 cis or trans tetrahydrocannabinol, and its optical isomers; 
(Since nomenclature of these substances is not internationally standardized, 
compounds of these structures, regardless of numerical designation of atomic 
positions covered.) 
(32) Ethylamine analog of phencyclidine (Other names: 
N-ethyl-1-phenylcyclohexylamine; (1-phenylcyclohexyl)ethylamine; 
N-(1-phenylcyclohexyl)ethylamine; cyclohexamine; PCE); 
(33) Pyrrolidine analog of phencyclidine (Other names: 1-(1 phenyl- 
cyclohexyl)-pyrrolidine; PCPy; PHP; rolicyclidine); 
(34) Thiophene analog of phencyclidine (Other names: 1-[1-(2-thienyl)­
cyclohexyl]-piperidine; 2-thienyl analog of phencyclidine; TPCP; TCP); 
(35) 1-[1-(2-Thienyl)cyclohexyl]pyrrolidine (Other name: TCPy); 
(36) 4-Methylmethcathinone (Other names: 4-methyl-N-methylcathinone; 
mephedrone); 
(37) 3,4-Methylenedioxypyrovalerone (Other name: MDPV); 
(38) 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (Other name: 2C-E); 
(39) 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (Other name: 2C-D); 
(40) 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (Other name: 2C-C);  
(41) 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (Other name: 2C-I); 
(42) 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (Other name: 2C-T­
2); 
(43) 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (Other name: 
2C-T-4); 
(44) 2-(2,5-Dimethoxyphenyl)ethanamine (Other name: 2C-H);  
(45) 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (Other name: 2C-N); 
(46) 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (Other name: 2C-P); 
(47) 3,4-Methylenedioxy-N-methylcathinone (Other name: Methylone); 
(48) (1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone 
(Other names: UR-144; 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(49) [1-(5-Fluoro-pentyl)-1H-indol-3-yl](2,2,3,3­
tetramethylcyclopropyl)methanone (Other names: 5-fluoro-UR-144; 5-F-UR-144; 
XLR11; (5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole); 
(50) N-(1-Adamantyl)-1-pentyl-1H-indazole-3-carboxamide (Other names: 
APINACA; AKB48); 
(51) Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (Other names: PB-22; 
QUPIC);  
(52) Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (Other names: 
5-fluoro-PB-22; 5F-PB-22); 
(53) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole­
3-carboxamide (Other name: AB-FUBINACA); 
(54) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3­
carboxamide (Other name: ADB-PINACA); 
(55) 2-(4-Iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine 
(Other names: 25I-NBOMe; 2CI-NBOMe; 25I; Cimbi-5); 
(56) 2-(4-Chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine 
(Other names: 25C-NBOMe; 2C-C-NBOMe; 25C; Cimbi-82); 
(57) 2-(4-Bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine 
(Other names: 25B-NBOMe; 2C-B-NBOMe; 25B; Cimbi-36); 
(58) Marihuana extract, meaning an extract containing one or more 
cannabinoids that has been derived from any plant of the genus Cannabis, other 
than separated resin (whether crude or purified) obtained from the plant; 
(59) 4-Methyl-N-ethylcathinone (Other name: 4-MEC);  
(60) 4-Methyl-α-pyrrolidinopropiophenone (Other name: 4-MePPP); 
(61) α-Pyrrolidinopentiophenone (Other name: [α]-PVP); 
(62) 1-(1,3-Benzodioxol-5-yl)-2-(methylamino)butan-1-one  
(Other names: butylone; bk-MBDB); 
(63) 2-(Methylamino)-1-phenylpentan-1-one (Other name: pentedrone); 
(64) 1-(1,3-Benzodioxol-5-yl)-2-(methylamino)pentan-1-one  
(Other names: pentylone; bk-MBDP); 
(65) 4-Fluoro-N-methylcathinone (Other names: 4-FMC; flephedrone); 
(66) 3-Fluoro-N-methylcathinone (Other name: 3-FMC); 
(67) 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (Other name: 
naphyrone);  
(68) α-Pyrrolidinobutiophenone (Other name: α-PBP); 
(69) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H­
indazole-3-carboxamide (Other name: AB-CHMINACA);  
(70) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3­
carboxamide (Other name: AB-PINACA); 
(71) [1-(5-Fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (Other 
name: THJ-2201); 
(72) 1-Methyl-4-phenyl-1,2,5,6-tetrahydro-pyridine (Other name: MPTP); 
(73) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexyl-methyl)-1H­
indazole-3-carboxamide (Other names: MAB-CHMINACA; ABD-CHMINACA);  

 
 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
  
 
 
 
 
 
 
 
(74) Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: 5F-ADB; 5F-MDMB-PINACA); 
(75) Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-caboxamido)-3­
methylbutanoate (Other name: 5F-AMB); 
(76) N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide 
(Other names: 5F-APINACA; 5F-AKB48); 
(77) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H­
indazole-3-carboxamide (Other name: ADB-FUBINACA); 
(78) Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: MDMB-CHMICA; MMB-CHMINACA); 
(79) Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other name: MDMB-FUBINACA); 
(80) Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3­
methylbutanoate (Other names: FUB-AMB; MMB-FUBINACA; AMB-FUBINACA); 
(81) Naphthalen-1-yl-1-(5-fluoropentyl)-1H-indole-3-carboxylate (Other 
names: NM2201; CBL2201); 
(82) N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole­
3-carboxamide (Other name: 5F-AB-PINACA); 
(83) 1-(4-Cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 
(Other names: 4-CN-CUMYL-BUTINACA; 4-cyano-CUMYL-BUTINACA; 4-CN-CUMYL­
BINACA; CUMYL-4CN-BINACA; SGT-78); 
(84) Methyl 2-(1-(Cyclohexylmethyl)-1H-indole-3-carboxamido)-3­
methylbutanoate (Other names: MMB-CHMICA; AMB-CHMICA); 
(85) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b]pyridine­
3-carboxamide (Other name: 5F-CUMYL-P7AICA); 
(86) 1-(1,3-Benzodioxol-5-yl)-2-(ethylamino)pentan-1-one (Other names: N­
ethylpentylone; ephylone); 
(87) Methyl 2-(1-(4-fluorobutyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate) (Other names: 4F-MDMB-BINACA; 4F-MDMB-BUTINACA); 
(88) 1-(4-Methoxyphenyl)-N-methylpropan-2-amine (Other names: p­
methoxymethamphetamine; PMMA); 
(89) Ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3­
dimethylbutanoate (Other name: 5F-EDMB-PINACA); 
(90) Methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3­
dimethylbutanoate (Other names: 5F-MDMB-PICA; 5F-MDMB-2201); 
(91) N-(Adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide 
(Other names: FUB-AKB48; FUB-APINACA; AKB48 N-(4-fluorobenzyl)); 
(92) 1-(5-Fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide 
(Other names: 5F-CUMYL-PINACA; SGT-25); 
(93) (1-(4-Fluorobenzyl)-1H-indol-3-yl)(2,2,3,3­
tetramethylcyclopropyl)methanone (Other name: FUB-144); 
(94) N-Ethylhexedrone (Other name: 2-(ethylamino)-1-phenylhexan-1-one); 
(95) α-Pyrrolidinohexanophenone (Other names: α-PHP; α­
pyrrolidinohexiophenone; 1-phenyl-2-(pyrrolidin-1-yl)hexan-1-one); 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
                           
 
 
                           
 
                           
 
                           
 
 
 
(96) 4-Methyl-α-ethylaminopentiophenone (Other names: 4–MEAP; 2­
(ethylamino)-1-(4-methylphenyl)pentan-1-one); 
(97) 4′-Methyl-α-pyrrolidinohexiophenone (Other names: MPHP; 4′-methyl­
α-pyrrolidinohexanophenone; 1-(4-methylphenyl)-2-(pyrrolidin-1-yl)hexan-1-one);  
(98) α-Pyrrolidinoheptaphenone (Other names: PV8; 1-phenyl-2-(pyrrolidin­
1-yl)heptan-1-one); 
(99) 4′-Chloro-α-pyrrolidinovalerophenone (Other names: 4-chloro-α-PVP; 
4′-chloro-α-pyrrolidinopentiophenone; 1-(4-chlorophenyl)-2-(pyrrolidin-1­
yl)pentan-1-one);  
(100) 2-(ethylamino)-2-(3-methoxyphenyl)cyclohexan-1-one (Other names: 
methoxetamine; MXE); 
(101) 1-(1,3-benzodioxol-5-yl)-2-(ethylamino)butan-1-one (Other names: 
eutylone; bk-EBDB); and, 
 
*(102) 1-(1,3-benzodioxol-5-yl)-2-(dimethylamino)pentan-1-one (other 
names: dipentylone, N,N-dimethylpentylone). 
-Schedule I Temporarily Listed Substances Subject to Emergency 
Scheduling by the U.S. Drug Enforcement Administration 
Unless specifically excepted or unless listed in another schedule, a material, 
compound, mixture, or preparation that contains any quantity of the following 
substances or that contains any of the substance's isomers, esters, ethers, salts 
and salts of isomers, esters, and ethers if the existence of the salts, esters, ethers 
isomers, and salts of isomers, esters, ethers is possible within the specific chemical 
designation:  
(1) Fentanyl-related substances. 
(1-1) Fentanyl-related substance means any substance not otherwise 
listed under another Administration Controlled Substance Code Number, and for 
which no exemption or approval is in effect under Section 505 of the Federal Food, 
Drug, and Cosmetic Act [21 U.S.C. 355], that is structurally related to fentanyl by 
one or more of the following modifications: 
(1-1-1) Replacement of the phenyl portion of the phenethyl 
group by any monocycle, whether or not further substituted in or on the 
monocycle; 
 (1-1-2) Substitution in or on the phenethyl group with alkyl, 
alkenyl, alkoxyl, hydroxyl, halo, haloalkyl, amino or nitro groups;
 (1-1-3) Substitution in or on the piperidine ring with alkyl, 
alkenyl, alkoxyl, ester, ether, hydroxyl, halo, haloalkyl, amino or nitro groups; 
 (1-1-4) Replacement of the aniline ring with any aromatic 
monocycle whether or not further substituted in or on the aromatic monocycle; 
and/or 
 (1-1-5) Replacement of the N-propionyl group by another acyl 
group. 

 
 
 
 
 
  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
(1–2) This definition includes, but is not limited to, the following 
substances: 
 
 
 
(1-2-1) N-(1-(2-Fluorophenethyl)piperidin-4­
yl)-N-(2-fluorophenyl)propionamide (Other name: 2′-fluoro-o-fluorofentanyl);
 
 
 
(1-2-2) N-(2-Methylphenyl)-N-(1­
phenethylpiperidin-4-yl)acetamide (Other name: o-methyl acetylfentanyl); 
 
 
 
(1-2-3) N-(1-Phenethylpiperidin-4-yl)-N,3-diphenylpropanamide 
(Other names: β′-phenyl fentanyl; hydrocinnamoyl fentanyl); and, 
 
 
 
(1-2-4) N-(1-Phenethylpiperidin-4-yl)-N-phenylthiophene-2­
carboxamide (Other name: thiofuranyl fentanyl). 
(2) 4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3­
α][1,4]diazepine (Other name: etizolam); 
 
(3) 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3­
α][1,4]diazepine (Other name: flualprazolam); 
 
(4) 6-(2-chlorophenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3­
α][1,4]diazepine (Other name: clonazolam); 
 
(5) 8-bromo-6-(2-fluorophenyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3­
α][1,4]diazepine (Other names: 8-bromo-6-(2-fluorophenyl)-1-methyl-4H­
[1,2,4]triazolo[4,3-α][1,4]benzodiazepine and flubromazolam); 
 
(6) 7-chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H­
benzo[e][1,4]diazepin-2-one (Other name: diclazepam); 
(7) Methyl 3,3-dimethyl-2-(1-(pent-4-en-1-yl)-1H-indazole-3­
carboxamido)butanoate (Other name: MDMB–4en–PINACA); 
(8) Methyl 2-[[1-(4-fluorobutyl)indole-3-carbonyl]amino]-3,3-dimethyl­
butanoate (Other names: 4F–MDMB–BUTICA; 4F–MDMB–BICA);
 
(9) N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(pent-4-en-1-yl)-1H­
indazole-3-carboxamide (Other name: ADB–4en–PINACA); 
 
(10) 5-Pentyl-2-(2-phenylpropan-2-yl)pyrido[4,3-b]indol-1-one (Other 
names: CUMYL–PEGACLONE; SGT–151);
 
(11) Ethyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl­
butanoate (Other names: 5F–EDMB–PICA; 5F–EDMB–2201); 
(12) Methyl 2-(1-(4-fluorobenzyl)-1H-indole-3-carboxamido)-3-methyl 
butanoate (Other name: MMB–FUBICA);
 
(13) N-ethyl-2-(2-(4-isopropoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)ethan­
1-amine (Other name: N-desethyl isotonitazene); 
 
(14) 2-(4-ethoxybenzyl)-5-nitro-1-(2-(piperidin-1-yl)ethyl)-1H-benzimidazole 
(Other names: N-piperidinyl etonitazene; etonitazepipne);
 
*(15) 2-(4-methoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H­
benzimidazole, its isomers, esters, ethers, salts and salts of isomers, esters and 
ethers (other names: N-pyrrolidinometonitazene; metonitazepyne); and,
 
*(16) 5-nitro-2-(4-propoxybenzyl)-1-(2-(pyrrolidin-1-yl)ethyl)-1H­
benzimidazole, its isomers, esters, ethers, salts and salts of isomers, esters and 
ethers (other names: N-pyrrolidino protonitazene; protonitazepyne); and 

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
________________________
 
 
 
 
_____________ 
*(17) 2-(2-((2,3-dihydrobenzofuran-5-yl)methyl)-5-nitro-1H-benzimidazol-1­
yl)-N,N-diethylethan-1-amine, its isomers, esters, ethers, salts, and salts of 
isomers, esters and ethers (other name: ethyleneoxynitazene); 
 
*(18) 2-(2-(benzodioxol-5-ylmethyl)-5-nitro-1H-benzimidazol-1-yl)-N,N­
diethylethan-1-amine, its isomers, esters, ethers, salts, and salts of isomers, esters 
and ethers (other names: methylenedioxynitazene; 3′,4′-methylenedioxynitazene);
 
*(19) 2-(2-(4-ethoxybenzyl)-5-methyl-1H-benzimidazol-1-yl)-N,N­
diethylethan-1-amine, its isomers, esters, ethers, salts, and salts of isomers, esters 
and ethers (other name: 5-methyl etodesnitazene);
 
*(20) 2-(2-(4-ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N-ethylethan-1­
amine, its isomers, esters, ethers, salts, and salts of isomers, esters and ethers 
(other name: N-desethyl etonitazene) 
 
*(21) N-ethyl-2-(5-nitro-2-(4-propoxybenzyl)-1H-benzimidazol-1-yl)ethan-1­
amine its isomers, esters, ethers, salts, and salts of isomers, esters and ethers 
(other name: N-desethyl protonitazene); 
 
*(22) 2-(2-(4-ethoxybenzyl)-5-nitro-1H-benzimidazol-1-yl)-N,N­
dimethylethan-1-amine, its isomers, esters, ethers, salts, and salts of isomers, 
esters and ethers (other name: N,N-dimethylamino etonitazene); and 
 
*(23) 2-(4-isopropoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H­
benzimidazole, its isomers, esters, ethers, salts, and salts of isomers, 
esters and ethers (other name: N-pyrrolidino isotonitazene). 
Jennifer Shuford, M.D., M.P.H. 
Date

Instrument

other

Source

https://capitol.texas.gov/tlodocs/85R/billtext/html/HB02671F.htm

Retrieved

2026-11-02

Fingerprint

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(6) Peyote, unless unharvested and growing in its natural state, meaning all parts of the plant classified botanically as Lophophora, whether growing or not, the seeds of the plant, an extract from a part of the plant, and every compound, manufacture, salt, derivative, mixture, or preparation of the plant, its seeds, or extracts;