Is EPN / Euphorinol Legal in Hawaii? (2026)

Edible / ingestible

Illegal

As of October 22, 2026, EPN / Euphorinol is illegal to sell at retail in Hawaii as edible / ingestible. Illegal - artificially-derived-cannabinoid ban (HRS 328G-1) reaches semi-synthetic EPN; mg caps moot. Effective 2024-12-06. Controlling source: HRS Sec. 328G-1 (artificially derived / synthetic cannabinoid definitions).

Verified October 22, 2026 (llm review) · confidence: confirmed
Rule type
permanent
Tier
schedule i
Limit
(total ban)
Effective
2024-12-06
Effectively prohibitive
HRS 328G-1 prohibits artificially-derived/synthetic cannabinoids; EPN is a semi-synthetic novel cannabinoid, so an EPN edible fails Hawaii's hemp definition regardless of its non-detect THC reading.

Controlling language, verbatim

HRS 328G-1 - 'Artificially derived cannabinoid means a chemical substance that is created by a chemical reaction that changes the molecular structure of any chemical substance derived from the plant genus cannabis.' (excludes decarboxylation without a chemical catalyst) 'Synthetic cannabinoid means a cannabinoid that is: (1) Produced artificially ... and (2) Not derived from the genus cannabis, including biosynthetic cannabinoids.'

Source of excerpt

Citations

  1. HRS Sec. 328G-1 (artificially derived / synthetic cannabinoid definitions) (Hawaii State Legislature) PRIMARYOFFICIAL
  2. Archive | Hemp Program (interim-rule version history) (Hawaii State Department of Health) PRIMARYOFFICIAL
  3. HAR 11-37 interim hemp rules summary (mg caps + food-form prohibition) (Hawaii Department of Health)OFFICIAL

Change history

  • Effective date changed from none to 2024-12-06.

Vape / inhalable

Illegal

As of October 25, 2026, EPN / Euphorinol is illegal to sell at retail in Hawaii as vape / inhalable. Illegal - artificially-derived-cannabinoid ban (HRS 328G-1) AND inhalable-hemp prohibition (HAR 11-37); doubly barred. Effective 2021-08-09. Controlling source: HRS Sec. 328G-1 (artificially derived / synthetic cannabinoid definitions).

Verified October 25, 2026 (llm review) · confidence: confirmed
Rule type
permanent
Tier
schedule i
Limit
(total ban)
Effective
2021-08-09
Effectively prohibitive
Two independent bans reach an EPN vape: HRS 328G-1 prohibits artificially-derived/synthetic cannabinoids (EPN is semi-synthetic), and HAR 11-37 prohibits inhalable hemp products outright.

Controlling language, verbatim

HRS 328G-1 - 'Artificially derived cannabinoid means a chemical substance that is created by a chemical reaction that changes the molecular structure of any chemical substance derived from the plant genus cannabis.' HAR 11-37 - 'Hemp flower material, hemp leaf, hemp cigarettes ... intended to be smoked or inhaled are prohibited. Inhalable hemp products are prohibited.'

Source of excerpt

Citations

  1. HRS Sec. 328G-1 (artificially derived / synthetic cannabinoid definitions) (Hawaii State Legislature) PRIMARYOFFICIAL
  2. HAR 11-37 interim hemp rules summary (inhalable-product prohibition) (Hawaii Department of Health) PRIMARYOFFICIAL
  3. Archive | Hemp Program (interim-rule version history) (Hawaii State Department of Health) PRIMARYOFFICIAL

Change history

  • Effective date changed from none to 2021-08-09.

Status by product form in Hawaii

FormStatusHeadlineVerified
Edible / ingestible IllegalIllegal - artificially-derived-cannabinoid ban (HRS 328G-1) reaches semi-synthetic EPN; mg caps moot2026-10-22
Vape / inhalable IllegalIllegal - artificially-derived-cannabinoid ban (HRS 328G-1) AND inhalable-hemp prohibition (HAR 11-37); doubly barred2026-10-25

Where EPN / Euphorinol stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Map and neighbor comparison show edible / ingestible. Open the interactive map · Every compound in Hawaii

Federal posture

Federally restricted. Contested hemp lane now; excluded as semi-synthetic at the Nov 12, 2026 cliff (P.L. 119-37 Sec. 781) Federal detail

Pending deadlines

  • 2026-11-12 · Federal · Federal hemp redefinition, Nov 12 slice: cannabinoids the plant cannot produce leave hemp (H.R. 5371 (Pub. L. 119-37, Sec. 781))
  • 2026-12-11 · Federal · Federal hemp redefinition, Dec 11 piece: total THC 0.3% and 0.4 mg total THC per container (H.R. 6500 (Pub. L. 119-103) / Pub. L. 119-37 Sec. 781)
    Pub. L. 119-103 (continuing resolution, Sept 2, 2026) delayed the rest of the Pub. L. 119-37 sec. 781 hemp definition to Dec 11, 2026 (CRS IF13136, Sept 28, 2026): hemp is measured by total tetrahydrocannabinols including THCA (0.3% dry weight), and any final product over 0.4 mg combined total THC and cannabinoids with similar effects per container leaves hemp. A product that leaves hemp is marijuana, Schedule I, in every state.

Verbatim law on file for Hawaii

4 instruments on file for this compound's framework in Hawaii; 6 of 6 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

Haw. Admin. R. 11-37-3 · Prohibited manufactured hemp productsOFFICIAL
Instrument
Prohibited manufactured hemp products
Source
https://health.hawaii.gov/hempprogram/consumers-of-mhp-faq/
Retrieved
2026-10-07
Fingerprint
235db61e54f06edc
Sale, hold for sale, offer or distribute of the following is PROHIBITED: Crude extract or MHP that is adulterated or misbranded; Crude extract or MHP that fails to meet applicable testing requirements; Any food into which a cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, hemp, hemp biomass, or MHP has been added as ingredient (this does not apply to hemp that is GRAS by FDA for use in foods, nor allowable edible MHP forms that are compliant with Sec.11-37-5: tablets, capsules, powders, softgels, gelcaps, oil-based tinctures, gummies, beverages); Crude extract or MHP that has total THC concentration above 0.3%; Vape or other product used to aerosolize for respiratory routes of delivery containing hemp-derived cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, or hemp; Hemp leaf, hemp floral material, including but not limited to hemp cigars or hemp cigarettes, viable seeds (this does not apply to sale of hemp leaf, hemp floral material, or viable seeds to a USDA licensed hemp producer or a DOH permitted hemp processor); MHP containing any viable seeds, leaf or floral materials; Except for external topically applied MHP, any product containing a hemp-derived cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, hemp, hemp biomass, or MHP as an ingredient intended to be introduced via non-oral routes of entry to body (i.e. eyes, ears and nasal cavities, etc.); Crude extract directly to a consumer (crude extract shall only be sold to a permitted hemp processor or person with equivalent authority from regulatory agency in another jurisdiction); Contents from an open package of MHP to a consumer; Advertising, packaging, labeling that contains health or benefit claims that are unsubstantiated, false, or misleading in any way. DOH implementing guidance (Consumers of MHP FAQ, current 12/16/2025): 'Hawaii prohibits the sale of MHP that contain artificially derived or synthetic cannabinoids. This includes cannabinoids like delta-8 THC, delta-10 THC, THCO, THC-P, THC-H, THCjd, HHC, HHCO, CBN created from any naturally occurring cannabinoid, like CBD, that was extracted from hemp biomass, or using a non-hemp substance, like yeast or algae, to produce any cannabinoid. State law only allows for cannabinoids naturally occurring in hemp to be extracted for use in manufactured hemp products.'
Haw. Admin. R. 11-37-3(e)-(f) (am. and comp. 2026-01-28); HRS ch. 328G · Haw. Admin. R. 11-37-3(e)-(f) (am. and comp. 2026-01-28); HRS ch. 328GOFFICIAL
Instrument
Haw. Admin. R. 11-37-3(e)-(f) (am. and comp. 2026-01-28); HRS ch. 328G
Source
https://health.hawaii.gov/hempprogram/files/2026/02/Standard11-37HAR-20260128.pdf
Retrieved
2026-10-07
Fingerprint
7e1f52470eecfb58
§11-37-3 Prohibitions. ... (e) [No person shall sell, hold for sale, offer, or distribute] "any other product containing hemp used to aerosolize for respiratory routes of delivery, such as an inhaler, vape pen" [or other device designed for such purpose.] (f) "No person shall sell, hold for sale, offer, or distribute any hemp leaf, hemp floral material," "including but not limited to hemp cigars or hemp cigarettes, or viable hemp seeds" [...]. (h) [Products intended for] "non-oral routes of entry to the body" [are prohibited, with listed exceptions]. §11-37-11(a) "Beginning January 1, 2026, no manufactured hemp product distributor or manufactured hemp product retailer shall sell" [manufactured hemp products] "without a certificate of registration." [Bracketed spans summarized; the DOH compilation is stamped JAN 28 2026.]
Haw. Admin. R. Sec.11-37-3 · Prohibitions on SaleOFFICIAL
Instrument
Prohibitions on Sale
Source
https://health.hawaii.gov/hempprogram/consumers-of-mhp-faq/
Retrieved
2026-07-19
Fingerprint
235db61e54f06edc
Sale, hold for sale, offer or distribute of the following is PROHIBITED: Crude extract or MHP that is adulterated or misbranded; Crude extract or MHP that fails to meet applicable testing requirements; Any food into which a cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, hemp, hemp biomass, or MHP has been added as ingredient (this does not apply to hemp that is GRAS by FDA for use in foods, nor allowable edible MHP forms that are compliant with Sec.11-37-5: tablets, capsules, powders, softgels, gelcaps, oil-based tinctures, gummies, beverages); Crude extract or MHP that has total THC concentration above 0.3%; Vape or other product used to aerosolize for respiratory routes of delivery containing hemp-derived cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, or hemp; Hemp leaf, hemp floral material, including but not limited to hemp cigars or hemp cigarettes, viable seeds (this does not apply to sale of hemp leaf, hemp floral material, or viable seeds to a USDA licensed hemp producer or a DOH permitted hemp processor); MHP containing any viable seeds, leaf or floral materials; Except for external topically applied MHP, any product containing a hemp-derived cannabinoid, artificially derived cannabinoid, synthetic cannabinoid, hemp, hemp biomass, or MHP as an ingredient intended to be introduced via non-oral routes of entry to body (i.e. eyes, ears and nasal cavities, etc.); Crude extract directly to a consumer (crude extract shall only be sold to a permitted hemp processor or person with equivalent authority from regulatory agency in another jurisdiction); Contents from an open package of MHP to a consumer; Advertising, packaging, labeling that contains health or benefit claims that are unsubstantiated, false, or misleading in any way. DOH implementing guidance (Consumers of MHP FAQ, current 12/16/2025): 'Hawaii prohibits the sale of MHP that contain artificially derived or synthetic cannabinoids. This includes cannabinoids like delta-8 THC, delta-10 THC, THCO, THC-P, THC-H, THCjd, HHC, HHCO, CBN created from any naturally occurring cannabinoid, like CBD, that was extracted from hemp biomass, or using a non-hemp substance, like yeast or algae, to produce any cannabinoid. State law only allows for cannabinoids naturally occurring in hemp to be extracted for use in manufactured hemp products.'
HRS 328G-1 · DefinitionsOFFICIAL
Instrument
Definitions
Source
https://www.capitol.hawaii.gov/hrscurrent/Vol06_Ch0321-0344/HRS0328G/HRS_0328G-0001.htm
Retrieved
2026-07-02
Fingerprint
823a943b28b715de
As used in this chapter:

"Applicant" means the person applying to register as a hemp processor under this chapter.

"Cannabinoids" means any of the various naturally occurring, biologically active, chemical constituents of cannabis that bind to or interact with receptors of the endogenous cannabinoid system.

"Cannabis" means the genus of the flowering plant in the family Cannabaceae. For the purpose of this chapter, cannabis refers to any form of the plant where the delta-9 tetrahydrocannabinol concentration on a dry weight basis has not yet been determined.

"Certificate of registration" means the certificate issued by the department attesting that the applicant is registered to process hemp.

"Decarboxylated" means the completion of the chemical reaction that converts delta-9 tetrahydrocannabinol's acids (THCA) into delta-9-tetrahydrocannabinol. The decarboxylated value may be calculated using a conversion formula that sums delta-9-tetrahydrocannabinol and eighty-seven and seven tenths (87.7) per cent of THCA.

"Delta-9 tetrahydrocannabinol" or "THC" means the primary psychoactive component of cannabis.

"Department" means the department of health.

"Director" means the director of health.

"Dry weight basis" refers to a method of determining the percentage of a chemical in a substance after removing the moisture from the substance.

"Enclosed indoor facility" means a permanent, stationary structure with a solid floor, rigid exterior walls that encircle the entire structure on all sides, and a roof that protects the entire interior area from the elements of weather. Nothing in this definition shall be construed to relieve the registered applicant from the applicant's duty to comply with all applicable building codes and regulations.

"FDA" means the United States Food and Drug Administration.

"Hemp" means Cannabis sativa L. and any part of that plant, whether growing or not, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, with a delta-9-tetrahydrocannabinol concentration of not more than 0.3 per cent on a dry weight basis, as measured post-decarboxylation or by other similarly reliable methods.

"Hemp processor" means a person processing hemp to manufacture a hemp product.

"Hemp product" means a product that:
(1) Contains naturally occurring cannabinoids, compounds, concentrates, extracts, isolates, resins or derivatives from processed hemp;
(2) Does not include any living hemp plants, viable seeds, leaf materials, or floral materials;
(3) Has a delta-9-tetrahydrocannabinol concentration of not more than 0.3 per cent, as measured post-decarboxylation, or other similarly reliable methods;
(4) Is intended to be consumed orally to supplement the human or animal diet; and
(5) Is in the form of a tablet, capsule, powder, softgel, gelcap, or liquid form (e.g. hemp oil) to be used by the consumer to infuse edible items at home for personal use or for topical application to the skin or hair.
For purposes of this chapter, a hemp product shall be considered as intended for oral ingestion in liquid form only if it is formulated in a fluid carrier and it is intended for ingestion in daily quantities measured in drops or similar small units of measure per labeled directions for use.

"Manufacture" means to compound, blend, extract, infuse, or otherwise make or prepare a hemp product, but does not include planting, growing, harvesting, drying, curing, grading, or trimming a hemp plant or part of a hemp plant.

"Person" means an individual, firm, corporation, partnership, association, or any form of business or legal entity.

"Processing" means making a transformative change to the hemp plant following harvest by converting an agricultural commodity into a hemp product.

"Synthetic cannabinoid" means a cannabinoid that is:
(1) Produced artificially, whether from chemicals or from recombinant biological agents including but not limited to yeast and algae; and
(2) Not derived from the genus cannabis, including biosynthetic cannabinoids.

Related

EPN / Euphorinol in other states

Same framework in Hawaii

Other compounds in Hawaii

Cite this page

Compound Analytics. "Is EPN / Euphorinol Legal in Hawaii? (2026)." Compound Laws, https://compoundlaws.com/compounds/epn/hawaii/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

About · Methodology · Glossary · Changes · Data & API · llms.txt · Sitemap