Is Endomorphin-1 Legal in Alabama? (2026)

Rule type

permanent

Tier

unscheduled

What the record says

Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in Alabama. The state has a controlled-substance analogue/designer-drug statute whose effect prong can satisfy the test without structural similarity. It still does not operatively reach EM-1 as sold (see effect-prong scope / 'specifically designed' / human-consumption gate in the detail). Controlling instrument reviewed: Ala. Code 20-2-23 (synthetic controlled substance analogue). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: low. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).

Controlling language, verbatim

Ala. Code 20-2-23(5)(a): "A synthetic controlled substance analogue, being a material, mixture, or preparation that contains any chemical structure of which is chemically similar to the chemical structure of any other controlled substance in Schedule I or Schedule II OR that satisfies any one of the following: 1. Has a stimulant, depressant, or hallucinogenic effect on the central nervous system that mimics or is similar to or greater than [that] of a controlled substance in Schedule I or Schedule II; 2. [represents/intends and is actually capable of such effect]; 3. Has been demonstrated to have binding activity at one or more cannabinoid receptors; 4. Is capable of exhibiting cannabinoid-like activity ..." (b) excludes approved-new-drug / investigational substances; (c) "A controlled substance analogue is treated as a controlled substance in Schedule I." [Effect prong = stimulant/depressant/hallucinogenic or cannabinoid activity; opioid analgesia does not fit, and 'chemically similar' structure fails for a peptide.]

Source of excerpt

Citations

1. Ala. Code 20-2-23 (synthetic controlled substance analogue) (Code mirror) PRIMARYOFFICIAL
2. Ala. Code 20-2-2(20) (opiate def, effect-based) (Code mirror)OFFICIAL

Where Endomorphin-1 stands across the country

Among Alabama's 4 neighbors, Florida, Georgia, Mississippi and Tennessee are legal, the same posture as Alabama.

Open the interactive map · Every compound in Alabama

Federal posture

Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail

Verbatim law on file for Alabama

1 instrument on file for this compound's framework in Alabama; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

"(280) 4-Hydroxy-N-methyl-N-ethyltryptamine (Some trade or other names: 4-OH-MET) (State Control Mar. 18, 2014)"
— Alabama Controlled Substances List (Board of Health Schedule I, Ala. Code § 20-2-23), official ADFS PDF: https://adfs.alabama.gov/Content/pdfs/drug-chemistry/2018%20Controlled%20Substance%20List.pdf

Related

Endomorphin-1 in neighboring states

• Endomorphin-1 in Florida Legal
• Endomorphin-1 in Georgia Legal
• Endomorphin-1 in Mississippi Legal
• Endomorphin-1 in Tennessee Legal

Endomorphin-1 in other states

Same framework in Alabama

• 4-HO-MET (Metocin) in Alabama Illegal
• 5-MAPB in Alabama Legal
• Blue Lotus (Nymphaea caerulea) in Alabama Legal
• Amanita muscaria / Muscimol in Alabama Legal

Other compounds in Alabama

Cite this page