Is Endomorphin-1 Legal in Oregon? (2026)

Legal

As of July 18, 2026, Endomorphin-1 is legal to sell at retail in Oregon. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: None - imitation CS only (ORS 475.912).

Verified July 18, 2026 · confidence: confirmed
Rule type
permanent
Tier
unscheduled

What the record says

Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in Oregon. The state has no chemical analogue statute; only an imitation / counterfeit / misrepresentation offense that turns on appearance or representation, not on a substance's intrinsic structure or effect. Controlling instrument reviewed: None - imitation CS only (ORS 475.912). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).

Controlling language, verbatim

ORS 475.912: "A person commits the crime of unlawful delivery of an imitation controlled substance if the person knowingly: (a) Delivers ... a substance that is not a controlled substance upon the express or implied representation that the substance is a controlled substance ..." Oregon has no analogue statute. [Representation only.]

Source of excerpt

Citations

  1. None - imitation CS only (ORS 475.912) (Oregon Legislature) PRIMARYOFFICIAL
  2. ORS 475.005 (opiate def) (Oregon Legislature)OFFICIAL

Where Endomorphin-1 stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among Oregon's 4 neighbors, California, Idaho, Nevada and Washington are legal, the same posture as Oregon.

Open the interactive map · Every compound in Oregon

Federal posture

Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail

Verbatim law on file for Oregon

2 instruments on file for this compound's framework in Oregon; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

OAR 855-080-0021 (Schedule I — federal incorporation + non-tryptamine structural classes); ORS 475.752 (prohibited acts — reaches only "controlled substance" / "counterfeit substance"); ORS 475.912 (imitation controlled substance)MIRROR
Instrument
statute
Source
https://oregon.public.law/rules/oar_855-080-0021
Retrieved
2026-06-19
Fingerprint
fb8e47873153c6de
**OAR 855-080-0021(1)–(2) (federal incorporation + structural classes)** — "Schedule I consists of the drugs and other substances … listed in 21CFR part 1308.11, and unless specifically excepted or unless listed in another schedule, any quantity of the following substances …" then "Schedule I also includes any compounds in the following structural classes …" (cannabinoids/cathinones/fentanyls/benzodiazepines only).
— OAR 855-080-0021, https://oregon.public.law/rules/oar_855-080-0021 (MIRROR: public.law). No tryptamine structural class; 4-HO-MET not named.
**ORS 475.752(1) (prohibited acts — no analog reach)** — "it is unlawful for any person to manufacture or deliver a controlled substance. Any person who violates this subsection with respect to: (a) A controlled substance in Schedule I, is guilty of a Class A felony …" — the section reaches only "controlled substance" and (subsection (2)) "counterfeit substance." There is **no** "controlled substance analog" offense.
— ORS 475.752, https://oregon.public.law/statutes/ors_475.752 (MIRROR: public.law; sources to oregonlegislature.gov). ORS 475.005 (definitions) contains no "controlled substance analog" definition; the only related offense is ORS 475.912 ("Unlawful delivery of imitation controlled substance").
OAR 855-080-0021 (Schedule I) as filed BP 8-2020, eff. 06/23/2020 · OAR 855-080-0021 (Schedule I) as filed BP 8-2020, eff. 06/23/2020OFFICIAL
Instrument
OAR 855-080-0021 (Schedule I) as filed BP 8-2020, eff. 06/23/2020
Source
https://records.sos.state.or.us/ORSOSWebDrawer/Record/7604711/File/document
Retrieved
2026-10-08
Fingerprint
b00bb0868fdfca45
RULE TITLE: Schedule I NOTICE FILED DATE: 04/21/2020 RULE SUMMARY: Schedule I controlled substances in Oregon RULE TEXT: (1) Schedule I consists of the drugs and other substances, by whatever official, common, usual, chemical, or brand name designated, listed in 21CFR part 1308.11, and unless specifically excepted or unless listed in another schedule, any quantity of the following substances, including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation: (a) 1,4-butanediol; (b) Gamma-butyrolactone (c) Methamphetamine, except as listed in OAR 855-080-0022; (d) Dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide (U-47700) (e) 4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]piperidin-2-ylidene]benzenesulfonamide (W-18) and positional isomers thereof, and any substituted derivative of W-18 and its positional isomers, and their salts, by any substitution on the piperidine ring (including replacement of all or part of the nitrophenylethyl group), any substitution on or replacement of the sulfonamide, or any combination of the above that are not FDA approved drugs, unless specifically excepted or when in the possession of an FDA registered manufacturer or a registered research facility, or a person for the purpose of sale to an FDA registered manufacturer or a registered research facility. (f) Substituted derivatives of cathinone and methcathinone that are not listed in OARs 855-080-0022 through 0026 (Schedules II through V) or are not FDA approved drugs, including but not limited to, (A) Methylmethcathinone (Mephedrone); (B) Methylenedioxypyrovalerone (MDPV); (C) Methylenedioxymethylcathinone (Methylone); (D) 2-Methylamino-3’,4’-(methylenedioxy)-butyrophenone (Butylone); (E) Fluoromethcathinone (Flephedrone); (F) 4-Methoxymethcathinone (Methedrone). (2) Schedule I also includes any compounds in the following structural classes (2a–2k) and their salts, that are not FDA approved drugs, unless specifically excepted or when in the possession of an FDA registered manufacturer or a registered research facility, or a person for the purpose of sale to an FDA registered manufacturer or a registered research facility: (a) Naphthoylindoles: Any compound containing a 3-(1-naphthoyl)indole structure with substitution at the nitrogen atom of the indole ring whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent. Examples of this structural class include but are not limited to: JWH-015, JWH-018, JWH-019, JWH-073, JWH-081, JWH-122, JWH-200, JWH-210, AM-1220, MAM-2201 and AM-2201; (b) Phenylacetylindoles: Any compound containing a 3-phenylacetylindole structure with substitution at the nitrogen atom of the indole ring whether or not further substituted in the indole ring to any extent, whether or not substituted in the phenyl ring to any extent. Examples of this structural class include but are not limited to: JWH-167, JWH -201, JWH-203, JWH-250, JWH-251, JWH-302 and RCS-8; (c) Benzoylindoles: Any compound containing a 3-(benzoyl)indole structure with substitution at the nitrogen atom of the indole ring whether or not further substituted in the indole ring to any extent and whether or not substituted in the phenyl ring to any extent. Examples of this structural class include but are not limited to: RCS-4, AM-694, AM-1241, and AM-2233; (d) Cyclohexylphenols: Any compound containing a 2-(3-hydroxycyclohexyl)phenol structure with substitution at the 5- position of the phenolic ring whether or not substituted in the cyclohexyl ring to any extent. Examples of this structural Page 2 of 4 class include but are not limited to: CP 47,497 and its C8 homologue (cannabicyclohexanol); (e) Naphthylmethylindoles: Any compound containing a 1H-indol-3-yl-(1-naphthyl)methane structure with substitution at the nitrogen atom of the indole ring whether or not further substituted in the indole ring to any extent and whether or not substituted in the naphthyl ring to any extent; (f) Naphthoylpyrroles: Any compound containing a 3-(1-naphthoyl)pyrrole structure with substitution at the nitrogen atom of the pyrrole ring whether or not further substituted in the pyrrole ring to any extent and whether or not substituted in the naphthyl ring to any extent; (g) Naphthylmethylindenes: Any compound containing a 1-(1-naphthylmethyl) indene structure with substitution at the 3-position of the indene ring whether or not further substituted in the indene ring to any extent and whether or not substituted in the naphthyl ring to any extent; (h) Cyclopropanoylindoles: Any compound containing an 3-(cyclopropylmethanoyl)indole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted in the indole ring to any extent and whether or not substituted in the cyclopropyl ring to any extent. Examples of this structural class include but are not limited to: UR- 144, XLR-11 and A-796,260; (i) Adamantoylindoles: Any compound containing a 3-(1-adamantoyl)indole structure with substitution at the nitrogen atom of the indole ring, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring to any extent. Examples of this structural class include but are not limited to: AM- 1248 and AB-001; (j) Adamantylindolecarboxamides: Any compound containing an N-adamantyl-1-indole-3-carboxamide with substitution at the nitrogen atom of the indole ring, whether or not further substituted in the indole ring to any extent and whether or not substituted in the adamantyl ring to any extent. Examples of this structural class include but are not limited to: STS-135 and 2NE1; and (k) Adamantylindazolecarboxamides: Any compound containing an N-adamantyl-1-indazole-3-carboxamide with substitution at the nitrogen atom of the indazole ring, whether or not further substituted in the indazole ring to any extent and whether or not substituted in the adamantyl ring to any extent. Examples of this structural class include but are not limited to: AKB48. (3) Schedule I also includes any other cannabinoid receptor agonist that is not listed in OARs 855-080-0022 through 0026 (Schedules II through V) or is not an FDA approved drug. (4) Schedule I also includes any substituted derivatives of fentanyl that are not listed in OARs 855-080-0022 through 0026 (Schedules II through V) or are not FDA approved drugs, and are derived from fentanyl by any substitution on or replacement of the phenethyl group, any substitution on the piperidine ring, any substitution on or replacement of the propanamide group, any substitution on the phenyl group, or any combination of the above. (5) Schedule I also includes any compounds in the following structural classes (a – b), and their salts, that are not listed in OARs 855-080-0022 through 0026 (Schedules II through V) or FDA approved drugs, unless specifically excepted or when in the possession of an FDA registered manufacturer or a registered research facility, or a person for the purpose of sale to an FDA registered manufacturer or a registered research facility: (a) Benzodiazepine class: A fused 1,4-diazepine and benzene ring structure with a phenyl connected to the diazepine ring, with any substitution(s) or replacement(s) on the 1,4-diazepine or benzene ring, any substitution(s) on the phenyl ring, or any combination thereof. Examples of this structural class include but are not limited to: Clonazolam, Flualprazolam (b) Thienodiazepine class: A fused 1,4-diazepine and thiophene ring structure with a phenyl connected to the 1,-4- diazepine ring, with any substitution(s) or replacement(s) on the 1,4-diazepine or thiophene ring, any substitution(s) on the phenyl ring, or any combination thereof. Examples of this structural class include but are not limited to: Etizolam (6) Exceptions. The following are exceptions to subsection (1) of this rule: (a) 1, 4-butanediol and gamma-butyrolactone when in the possession of a person for the purpose of its sale to a legitimate manufacturer of industrial products and the person is in compliance with the Drug Enforcement Administration requirements for List I Chemicals; Page 3 of 4 (b) 1, 4-butanediol and gamma-butyrolactone when in the possession of a person for the purpose of the legitimate manufacture of industrial products; (c) Marijuana and delta-9-tetrahydrocannabinol (THC).

Related

Endomorphin-1 in neighboring states

Endomorphin-1 in other states

Same framework in Oregon

Other compounds in Oregon

Cite this page

Compound Analytics. "Is Endomorphin-1 Legal in Oregon? (2026)." Compound Laws, https://compoundlaws.com/compounds/endomorphin-1/oregon/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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