As of July 18, 2026, Endomorphin-1 is legal to sell at retail in Maryland. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: None - distributing faked CDS only (Md. Crim. Law 5-617).
Verified July 18, 2026 · confidence: confirmedEndomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in Maryland. The state has no chemical analogue statute; only an imitation / counterfeit / misrepresentation offense that turns on appearance or representation, not on a substance's intrinsic structure or effect. Controlling instrument reviewed: None - distributing faked CDS only (Md. Crim. Law 5-617). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).
Md. Crim. Law 5-617(a): "A person may not distribute ... a noncontrolled substance: (1) that the person represents as a controlled dangerous substance; (2) that the person intends for use ... as a controlled dangerous substance; or (3) under circumstances where one reasonably should know that the noncontrolled substance will be used ... as a controlled dangerous substance." (b)(3) considers "whether the physical appearance ... is substantially identical to that of a controlled dangerous substance." Maryland has no structural-analogue statute. [Representation/appearance only.]
Among Maryland's 5 neighbors, District of Columbia, Delaware, Pennsylvania, Virginia and West Virginia are legal, the same posture as Maryland.
Open the interactive map · Every compound in Maryland
Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail
2 instruments on file for this compound's framework in Maryland; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
ff39c7d9766e1749**§ 5-402(a)(1) & (b):** "(a) Schedule I consists of each: (1) controlled dangerous substance analogue, as defined in subsection (b) of this section …" and "(b)(1)(i) 'controlled dangerous substance analogue' means a substance: 1. that has a chemical structure substantially similar to the chemical structure of a controlled dangerous substance described in Schedule I or Schedule II; and 2. that has a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than [that] of a controlled dangerous substance described in Schedule I or Schedule II …" and "(2) To the extent intended for human consumption, each controlled dangerous substance analogue is a substance described in Schedule I." — Md. Code, Crim. Law § 5-402; via labeled Justia mirror: https://law.justia.com/codes/maryland/criminal-law/title-5/subtitle-4/section-5-402/
acfde5ec795d04e3(a) Schedule I consists of each: (1) controlled dangerous substance analogue, as defined in subsection (b) of this section; (2) controlled dangerous substance added to Schedule I by the Department under Section 5-202(b) of this title; and (3) controlled dangerous substance designated as a Schedule I controlled dangerous substance by the federal government unless the Department objects under Section 5-202(f) of this title. (b) (1) In this subsection: (i) 'controlled dangerous substance analogue' means a substance: 1. that has a chemical structure substantially similar to the chemical structure of a controlled dangerous substance described in Schedule I or Schedule II; and 2. that has a stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled dangerous substance described in Schedule I or Schedule II; but (ii) 'controlled dangerous substance analogue' does not include: 1. a controlled dangerous substance; 2. a substance for which there is an approved new drug application; or 3. a substance exempted for investigational use under Section 506 of the Federal Food, Drug, and Cosmetic Act. (2) To the extent intended for human consumption, each controlled dangerous substance analogue is a substance described in Schedule I. (c) The Department may not add a substance to Schedule I under Section 5-202 of this title unless the Department finds: (1) a high potential for abuse of the substance; (2) no accepted medical use in the United States for the substance; and (3) a lack of accepted safety for use of the substance under medical supervision.
Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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