As of July 18, 2026, Endomorphin-1 is legal to sell at retail in Delaware. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: 16 Del. C. 4701 (designer drug).
Verified July 18, 2026 · confidence: confirmedEndomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in Delaware. The state has a controlled-substance analogue/designer-drug statute whose effect prong can satisfy the test without structural similarity. It still does not operatively reach EM-1 as sold (see effect-prong scope / 'specifically designed' / human-consumption gate in the detail). Controlling instrument reviewed: 16 Del. C. 4701 (designer drug). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: low. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).
16 Del. C. 4701(10): "'Designer drug' means a substance that has a chemical structure substantially similar to that of a controlled substance or that was specifically designed to or may produce an effect substantially similar to that of a controlled substance. Examples of chemical classes ... include ... Phenethylamines, N-substituted piperidines, morphinans, ecgonines, quinazolinones, substituted indoles, arylcycloalkylamines, cannabinoids, cathinones ..." Excludes approved-new-drug / investigational substances. [Targets clandestine 'designed' small-molecule analogues.]
Among Delaware's 3 neighbors, Maryland, New Jersey and Pennsylvania are legal, the same posture as Delaware.
Open the interactive map · Every compound in Delaware
Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail
2 instruments on file for this compound's framework in Delaware; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
68691bb2616a99d4**§ 4714(d)** "Any material, compound, mixture or preparation which contains any quantity of the following hallucinogenic substances, their salts, isomers and salts of isomers, unless specifically excepted, whenever the existence of these salts, isomers, and salts of isomers is possible within the specific chemical designation: … (4) Bufotenine; (5) Diethyltryptamine; (6) Dimethyltryptamine; … (14) Psilocybin; (15) Psilocyn; … (23) Alpha-ethyltrytamine [sic]." — 16 Del. C. § 4714(d), official Delaware Code Online: https://delcode.delaware.gov/title16/c047/sc02/index.html (4-HO-MET not named; no tryptamine structural class)
05e12a90636e64b4(7) Controlled substance means a drug, substance or immediate precursor in Schedules I through V of subchapter II of this chapter. For purposes of the crimes set forth in subchapters IV and V of this chapter, and of forfeiture set forth in Section 4784 of this title, controlled substance includes designer drug, as defined in paragraph (10) of this section. (10) Designer drug means a substance that has a chemical structure substantially similar to that of a controlled substance or that was specifically designed to or may produce an effect substantially similar to that of a controlled substance. Examples of chemical classes in which designer drugs are found include, but are not limited to, the following: Phenethylamines, N-substituted piperidines, morphinans, ecgonines, quinazolinones, substituted indoles, arylcycloalkylamines, cannabinoids, cathinones, and any synthetic analogue of a controlled substance. Designer drug does not include any substance that was manufactured, delivered or dispensed in conformance with an approved new drug application, or an exemption for investigating use within the meaning of Section 505 of the Federal Food, Drug and Cosmetic Act (21 U.S.C. Section 355), or that was manufactured, delivered or dispensed in conformance with a registration issued by the Attorney General of the United States within the meaning of Sections 301-304 of the Federal Controlled Substances Act (21 U.S.C. Sections 821-824).
Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.
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