Home / Compounds / Endomorphin-1 / North Dakota

Is Endomorphin-1 Legal in North Dakota? (2026)

Legal

As of July 18, 2026, Endomorphin-1 is legal to sell at retail in North Dakota. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: N.D.C.C. 19-03.1-01(7) (controlled substance analog).

Verified July 18, 2026 · confidence: confirmed
Rule type
permanent
Tier
unscheduled

What the record says

Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in North Dakota. The state has a controlled-substance analogue statute whose similarity test is CONJUNCTIVE (chemical structure substantially similar to a scheduled substance AND a substantially similar CNS effect). The structure prong fails for a tetrapeptide, so the statute does not reach EM-1. Controlling instrument reviewed: N.D.C.C. 19-03.1-01(7) (controlled substance analog). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).

Controlling language, verbatim

N.D.C.C. 19-03.1-01(7): "Means a substance the chemical structure of which is substantially similar to the chemical structure of a controlled substance in a schedule I or II AND: (1) Which has a stimulant, depressant, or hallucinogenic effect on the central nervous system which is substantially similar to or greater than ...; or (2) ... which the individual represents or intends ..." [Conjunctive - structure prong fails.]

Source of excerpt

Citations

  1. N.D.C.C. 19-03.1-01(7) (controlled substance analog) (North Dakota Legislature) PRIMARYOFFICIAL
  2. N.D.C.C. 19-03.1-01(19) (opiate def) (North Dakota Legislature)OFFICIAL

Where Endomorphin-1 stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among North Dakota's 3 neighbors, Minnesota, Montana and South Dakota are legal, the same posture as North Dakota.

Open the interactive map · Every compound in North Dakota

Federal posture

Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail

Verbatim law on file for North Dakota

2 instruments on file for this compound's framework in North Dakota; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

N.D. Cent. Code § 19-03.1-05(6)(p)(3) — named; and § 19-03.1-05(6)(p) — substituted-tryptamine structural classOFFICIAL
Instrument
statute
Source
https://ndlegis.gov/cencode/t19c03-1.pdf
Retrieved
2026-06-19
Fingerprint
4cb3baa5f02f9276
**Named entry** — "(3) 4-hydroxy-N-methyl-N-ethyltryptamine (also known as 4-HO-MET)."
— N.D. Cent. Code § 19-03.1-05(6)(p)(3), https://ndlegis.gov/cencode/t19c03-1.pdf (OFFICIAL — ND Legislative Branch).
**Structural class** — "p. Substituted tryptamines. This includes any compound, unless specifically excepted, specifically named in this schedule, or listed under a different schedule, structurally derived from 2-(1H-indol-3-yl)ethanamine (i.e., tryptamine) by mono- or di-substitution of the amine nitrogen with alkyl or alkenyl groups or by inclusion of the amino nitrogen atom in a cyclic structure whether or not the compound is further substituted at the alpha-position with an alkyl group or whether or not further substituted on the indole ring to any extent with any alkyl, alkoxy, halo, hydroxyl, or acetoxy groups."
— N.D. Cent. Code § 19-03.1-05(6)(p). Same URL (OFFICIAL).
N.D. Cent. Code Sec. 19-03.1-05 (Substituted phenethylamines) · Schedule I - Substituted phenethylamines (with named benzofurans)OFFICIAL
Instrument
Schedule I - Substituted phenethylamines (with named benzofurans)
Source
https://ndlegis.gov/cencode/t19c03-1.pdf
Retrieved
2026-07-20
Fingerprint
239f1dfe88c93107
o. Substituted phenethylamines. This includes any compound, unless specifically excepted, specifically named in this schedule, or listed under a different schedule, structurally derived from phenylethan-2-amine by substitution on the phenyl ring in any of the following ways, that is to say, by substitution with a fused methylenedioxy ring, fused furan ring, or fused tetrahydrofuran ring; by substitution with two alkoxy groups; by substitution with one alkoxy and either one fused furan, tetrahydrofuran, or tetrahydropyran ring system; or by substitution with two fused ring systems from any combination of the furan, tetrahydrofuran, or tetrahydropyran ring systems. (1) Whether or not the compound is further modified in any of the following ways, that is to say: (a) By substitution of phenyl ring by any halo, hydroxyl, alkyl, trifluoromethyl, alkoxy, or alkylthio groups; (b) By substitution at the 2-position by any alkyl groups; or (c) By substitution at the 2-amino nitrogen atom with alkyl, dialkyl, benzyl, hydroxybenzyl, methylenedioxybenzyl, or methoxybenzyl groups. (2) Examples include: (a) 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (also known as 2C-C or 2,5-Dimethoxy-4-chlorophenethylamine). (b) 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (also known as 2C-D or 2,5-Dimethoxy-4-methylphenethylamine). (c) 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (also known as 2C-E or 2,5-Dimethoxy-4-ethylphenethylamine). (d) 2-(2,5-Dimethoxyphenyl)ethanamine (also known as 2C-H or 2,5-Dimethoxyphenethylamine). (e) 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (also known as 2C-I or 2,5-Dimethoxy-4-iodophenethylamine). (f) 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (also known as 2C-N or 2,5-Dimethoxy-4-nitrophenethylamine). (g) 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (also known as 2C-P or 2,5-Dimethoxy-4-propylphenethylamine). (h) 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (also known as 2CT-2 or 2,5-Dimethoxy-4-ethylthiophenethylamine). (i) 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (also known as 2C-T-4 or 2,5-Dimethoxy-4-isopropylthiophenethylamine). (j) 2-(4-bromo-2,5-dimethoxyphenyl)ethanamine (also known as 2C-B or 2,5-Dimethoxy-4-bromophenethylamine). (k) 2-(2,5-dimethoxy-4-(methylthio)phenyl)ethanamine (also known as 2C-T or 4-methylthio-2,5-dimethoxyphenethylamine). (l) 1-(2,5-dimethoxy-4-iodophenyl)-propan-2-amine (also known as DOI or 2,5-Dimethoxy-4-iodoamphetamine). (m) 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane (also known as DOB or 2,5-Dimethoxy-4-bromoamphetamine). (n) 1-(4-chloro-2,5-dimethoxy-phenyl)propan-2-amine (also known as DOC or 2,5-Dimethoxy-4-chloroamphetamine). (o) 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (also known as 2C-B-NBOMe; 2,5B-NBOMe or 2,5-Dimethoxy-4-bromo-N-(2-methoxybenzyl)phenethylamine). (p) 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (also known as 2C-I-NBOMe; 2,5I-NBOMe or 2,5-Dimethoxy-4-iodo-N-(2-methoxybenzyl)phenethylamine). (q) N-(2-Methoxybenzyl)-2-(3,4,5-trimethoxyphenyl)ethanamine (also known as mescaline-NBOMe or 3,4,5-trimethoxy-N-(2-methoxybenzyl)phenethylamine). (r) 2-(4-chloro-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (also known as 2C-C-NBOMe; 2,5C-NBOMe or 2,5-Dimethoxy-4-chloro-N-(2-methoxybenzyl)phenethylamine). (s) 2-(7-Bromo-5-methoxy-2,3-dihydro-1-benzofuran-4-yl)ethanamine (also known as 2CB-5-hemiFLY). (t) 2-(8-bromo-2,3,6,7-tetrahydrofuro [2,3-f][1]benzofuran-4-yl)ethanamine (also known as 2C-B-FLY). (u) 2-(10-Bromo-2,3,4,7,8,9-hexahydropyrano[2,3-g]chromen-5-yl)ethanamine (also known as 2C-B-butterFLY). (v) N-(2-Methoxybenzyl)-1-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b']difuran-4-yl)-2-aminoethane (also known as 2C-B-FLY-NBOMe). (w) 1-(4-Bromofuro[2,3-f][1]benzofuran-8-yl)propan-2-amine (also known as bromo-benzodifuranyl-isopropylamine or bromo-dragonFLY). (x) N-(2-Hydroxybenzyl)-4-iodo-2,5-dimethoxyphenethylamine (also known as 2C-I-NBOH or 2,5I-NBOH). (y) 5-(2-Aminopropyl)benzofuran (also known as 5-APB). (z) 6-(2-Aminopropyl)benzofuran (also known as 6-APB). (aa) 5-(2-Aminopropyl)-2,3-dihydrobenzofuran (also known as 5-APDB). (bb) 6-(2-Aminopropyl)-2,3,-dihydrobenzofuran (also known as 6-APDB). (cc) 2,5-dimethoxy-amphetamine (also known as 2,5-dimethoxy-amethylphenethylamine; 2,5-DMA). (dd) 2,5-dimethoxy-4-ethylamphetamine (also known as DOET). (ee) 2,5-dimethoxy-4-(n)-propylthiophenethylamine (also known as 2C-T7). (ff) 5-methoxy-3,4-methylenedioxy-amphetamine. (gg) 4-methyl-2,5-dimethoxy-amphetamine (also known as 4-methyl-2,5-dimethoxy-amethylphenethylamine; DOM and STP). (hh) 3,4-methylenedioxy amphetamine (also known as MDA). (ii) 3,4-methylenedioxymethamphetamine (also known as MDMA). (jj) 3,4-methylenedioxy-N-ethylamphetamine (also known as N-ethylalpha-methyl-3,4(methylenedioxy)phenethylamine, MDE, MDEA). (kk) 3,4,5-trimethoxy amphetamine. (ll) Mescaline (also known as 3,4,5-trimethoxyphenethylamine).

Related

Endomorphin-1 in neighboring states

Endomorphin-1 in other states

Same framework in North Dakota

Other compounds in North Dakota

Cite this page

Compound Analytics. "Is Endomorphin-1 Legal in North Dakota? (2026)." Compound Laws, https://compoundlaws.com/compounds/endomorphin-1/north-dakota/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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