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Is Endomorphin-1 Legal in New Jersey? (2026)

Legal

As of July 18, 2026, Endomorphin-1 is legal to sell at retail in New Jersey. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: N.J.S.A. 2C:35-2 (analog; conjunctive + 'specifically designed'; no standalone analog offense).

Verified July 18, 2026 · confidence: confirmed
Rule type
permanent
Tier
unscheduled

What the record says

Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in New Jersey. The state has a controlled-substance analogue statute whose similarity test is CONJUNCTIVE (chemical structure substantially similar to a scheduled substance AND a substantially similar CNS effect). The structure prong fails for a tetrapeptide, so the statute does not reach EM-1. Controlling instrument reviewed: N.J.S.A. 2C:35-2 (analog; conjunctive + 'specifically designed'; no standalone analog offense). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).

Controlling language, verbatim

N.J.S.A. 2C:35-2: "'Controlled substance analog' means a substance that has a chemical structure substantially similar to that of a controlled dangerous substance AND that was specifically designed to produce an effect substantially similar to that of a controlled dangerous substance." Excludes approved-new-drug / investigational substances. No standalone analog offense (only the representation-based imitation offense, 2C:35-11). [Conjunctive + 'specifically designed' - excludes an endogenous ligand.]

Source of excerpt

Citations

  1. N.J.S.A. 2C:35-2 (analog; conjunctive + 'specifically designed'; no standalone analog offense) (Code mirror) PRIMARYOFFICIAL
  2. N.J.S.A. 2C:35-2 (opiate def) (Code mirror)OFFICIAL

Where Endomorphin-1 stands across the country

LegalRestrictedGray areaIllegalNot yet verified

Among New Jersey's 3 neighbors, Delaware, New York and Pennsylvania are legal, the same posture as New Jersey.

Open the interactive map · Every compound in New Jersey

Federal posture

Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail

Verbatim law on file for New Jersey

3 instruments on file for this compound's framework in New Jersey; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

N.J.A.C. 13:45H-10.1 (NJ Schedule I incorporates federal 21 CFR 1308.11 by reference); N.J.S.A. 2C:35-2 (controlled substance analog)MIRROR
Instrument
statute
Source
https://www.law.cornell.edu/regulations/new-jersey/N-J-A-C-13-45H-10-1
Retrieved
2026-06-19
Fingerprint
b2544b6f71d19e60
**N.J.A.C. 13:45H-10.1(a) (federal incorporation)** — "The Federal controlled dangerous substance Schedules I, II, III, IV and V at 21 CFR 1308.11 through 1308.15, as amended and supplemented, promulgated by the United States Attorney General pursuant to 21 U.S.C. §§ 811 and 812, are incorporated herein by reference."
— N.J.A.C. 13:45H-10.1(a), https://www.law.cornell.edu/regulations/new-jersey/N-J-A-C-13-45H-10-1 (OFFICIAL — Cornell LII reproduction of N.J.A.C.).
**N.J.S.A. 2C:35-2 (controlled substance analog)** — "'Controlled substance analog' means a substance that has a chemical structure substantially similar to that of a controlled dangerous substance and that was specifically designed to produce an effect substantially similar to that of a controlled dangerous substance. The term shall not include a substance manufactured or distributed in conformance with the provisions of an approved new drug application or an exemption for investigational use within the meaning of section 505 of the 'Federal Food, Drug and Cosmetic Act' …" — and: "The term [controlled dangerous substance], wherever it appears in any law or administrative regulation of this State, shall include controlled substance analogs."
— N.J.S.A. 2C:35-2, https://law.justia.com/codes/new-jersey/title-2c/section-2c-35-2/ (MIRROR: Justia).
N.J.A.C. 13:45H-10.1 (Schedules of CDS; adopts federal 21 CFR 1308.11-.15 plus state additions), 2017 adoption notice · N.J.A.C. 13:45H-10.1 (Schedules of CDS; adopts federal 21 CFR 1308.11-.15 plus state additions), 2017 adoption noticeOFFICIAL
Instrument
N.J.A.C. 13:45H-10.1 (Schedules of CDS; adopts federal 21 CFR 1308.11-.15 plus state additions), 2017 adoption notice
Source
https://WWW.NJCONSUMERAFFAIRS.GOV/Adoptions/060517-CDS-Adoption.pdf
Retrieved
2026-10-08
Fingerprint
634785e900e19af8
Although New Jersey has adopted, in N.J.A.C. 13:45H-10.1(a), the Federal controlled dangerous substances Schedules I through V codified at 21 CFR 1308.11 through 1308.15, as amended and supplemented, the Director is authorized under N.J.S.A. 24:21-3 to add, delete, or reschedule substances under the New Jersey Controlled Dangerous Substances Act. Full text of the adoption follows: 13:45H-10.1 Schedules of controlled dangerous substances (a)-(d) (No change.) (e) In accordance with (d) above, the following substances shall be designated and controlled as Schedule I controlled dangerous substances: 1.-9. (No change.) 10. Illicit fentanyls. Illicit fentanyls include any material, compound, mixture, or preparation that is not listed as a controlled substance in Schedules I through V, is not a Federal Food and Drug Administration (FDA) approved drug, and contains any quantity of the following substances, their salts, isomers (whether optical, positional, or geometric), homologues (analogs), and salts of isomers, and homologues (analogs) unless specifically excepted whenever the existence of these salts, isomers, homologues (analogs), and salts of isomers and homologues (analogs) is possible within the specific chemical designations: i. Furanyl Fentanyl, with a chemical composition of N-phenyl-N-[1-(2-phenylethyl)-4- piperidinyl] -2-furancarboxamide, monohydrochloride or N-(1-phenethylpiperidin-4-yl)-N- phenylfuran-2-carboxamide; ii. 3-Methylfentanyl, with a chemical composition of 3-methyl-N-phenyl-N-[1-(2-phenethyl- 4-piperidyl)-propanamide); iii. 3-Methyl Butyrylfentanyl, with a chemical composition of 3-Methyl, N-phenyl-N-[1-(2- phenylethyl)-4-piperidinyl]-butanamide, monohydrochloride; iv. Valeryl Fentanyl, with a chemical composition of N-phenyl-N-[1-(2-phenylethyl)-4- piperidinyl]-pentanamide, monohydrochloride; v. Norfentanyl, with a chemical composition of N-phenyl-N-4-piperidinyl-propanamide; vi. Para-Fluorobutyryl-Fentanyl, with a chemical composition of N-(4-fluorophenyl)-N-[1-(2- phenylethyl)-4-piperidinyl]-butanamide, monohydrochloride; and vii. Carfentanyl, with a chemical composition of 2-hydroxypropane-1, 2, 3-tricarboxylic acid; methyl 1-(2-phenylethyl)-4-(N-propanoylanilino) piperidine-4-carboxylateor.
N.J.S.A. Sec. 2C:35-2 (Definitions) · Controlled dangerous substance / Controlled substance analog (analogs folded into CDS)MIRROR
Instrument
Controlled dangerous substance / Controlled substance analog (analogs folded into CDS)
Source
https://law.justia.com/codes/new-jersey/title-2c/section-2c-35-2/
Retrieved
2026-07-20
Fingerprint
b16e837424533ac6
"Controlled dangerous substance" means a drug, substance, or immediate precursor in Schedules I through V, marijuana and hashish as defined in this section, any substance the distribution of which is specifically prohibited in N.J.S.2C:35-3, in section 3 of P.L.1997, c.194 (C.2C:35-5.2), in section 5 of P.L.1997, c.194 (C.2C:35-5.3), in section 2 of P.L.2011, c.120 (C.2C:35-5.3a), or in section 2 of P.L.2013, c.35 (C.2C:35-5.3b), and any drug or substance which, when ingested, is metabolized or otherwise becomes a controlled dangerous substance in the human body. When any statute refers to controlled dangerous substances, or to a specific controlled dangerous substance, it shall also be deemed to refer to any drug or substance which, when ingested, is metabolized or otherwise becomes a controlled dangerous substance or the specific controlled dangerous substance, and to any substance that is an immediate precursor of a controlled dangerous substance or the specific controlled dangerous substance. The term shall not include distilled spirits, wine, malt beverages, as those terms are defined or used in R.S.33:1-1 et seq., tobacco and tobacco products, or cannabis and cannabis as defined in section 3 of P.L.2021, c.16 (C.24:6I-33). The term, wherever it appears in any law or administrative regulation of this State, shall include controlled substance analogs. "Controlled substance analog" means a substance that has a chemical structure substantially similar to that of a controlled dangerous substance and that was specifically designed to produce an effect substantially similar to that of a controlled dangerous substance. The term shall not include a substance manufactured or distributed in conformance with the provisions of an approved new drug application or an exemption for investigational use within the meaning of section 505 of the "Federal Food, Drug and Cosmetic Act," 52 Stat. 1052 (21 U.S.C. s.355).

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Cite this page

Compound Analytics. "Is Endomorphin-1 Legal in New Jersey? (2026)." Compound Laws, https://compoundlaws.com/compounds/endomorphin-1/new-jersey/. Accessed October 25, 2026.

Compound Laws, published by Compound Analytics, reports the record: statutes verbatim, official citations, enforcement facts and verification dates. Nothing here is legal advice and nothing here describes how to get around a law. A jurisdiction with no verified row is reported as not yet verified, never as legal. Found an error? Corrections policy.

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