Is Endomorphin-1 Legal in Rhode Island? (2026)

Rule type

permanent

Tier

unscheduled

What the record says

Endomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in Rhode Island. The state has no chemical analogue statute; only an imitation / counterfeit / misrepresentation offense that turns on appearance or representation, not on a substance's intrinsic structure or effect. Controlling instrument reviewed: None - imitation CS only (R.I. Gen. Laws 21-28-1.02(24)). Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).

Controlling language, verbatim

R.I. Gen. Laws 21-28-1.02(24): "'Imitation controlled substance' means a substance that is not a controlled substance, that by dosage unit, appearance (including color, shape, size, and markings), or by representations made, would lead a reasonable person to believe that the substance is a controlled substance ..." No analogue statute. [Appearance/representation only.]

Source of excerpt

Citations

1. None - imitation CS only (R.I. Gen. Laws 21-28-1.02(24)) (Rhode Island Legislature) PRIMARYOFFICIAL
2. R.I. Gen. Laws 21-28-1.02(32) (opiate def) (Rhode Island Legislature)OFFICIAL

Where Endomorphin-1 stands across the country

Among Rhode Island's 2 neighbors, Connecticut and Massachusetts are legal, the same posture as Rhode Island.

Open the interactive map · Every compound in Rhode Island

Federal posture

Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail

Verbatim law on file for Rhode Island

1 instrument on file for this compound's framework in Rhode Island; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.

**R.I. Gen. Laws § 21-28-2.08(d) (Schedule I hallucinogens — current)** — "Hallucinogenic Substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation that contains any quantity of the following hallucinogenic substances, or that contains any of its salts, isomers, and salts of isomers whenever the existence of the salts, isomers, and salts of isomers is possible within the specific chemical designation (for purposes of this subsection only, the term 'isomer' includes the optical, position, and geometric isomers): … (4) Bufotenine … (5) Diethyltryptamine … (6) Dimethyltryptamine … (15) Psilocybin (16) Psilocyn …"
— R.I. Gen. Laws § 21-28-2.08(d), https://webserver.rilegislature.gov/Statutes/TITLE21/21-28/21-28-2.08.htm (OFFICIAL — RI General Assembly; pulled June 19, 2026; History line ends at P.L. 2017, ch. 53/59). 4-HO-MET does not appear, and no tryptamine structural class exists in the section.
**R.I. Gen. Laws § 21-28-1.02(25) (imitation controlled substance — appearance-based, NOT a structural analog)** — "'Imitation controlled substance' means a substance that is not a controlled substance, that by dosage unit, appearance (including color, shape, size, and markings), or by representations made, would lead a reasonable person to believe that the substance is a controlled substance …"
— R.I. Gen. Laws § 21-28-1.02(25), https://law.justia.com/codes/rhode-island/2021/title-21/chapter-21-28/section-21-28-1-02/ (MIRROR: Justia). The definitions section contains no "analog"/"analogue"/"substantially similar chemical structure" provision.

Related

Endomorphin-1 in neighboring states

• Endomorphin-1 in Connecticut Legal
• Endomorphin-1 in Massachusetts Legal

Endomorphin-1 in other states

Same framework in Rhode Island

• 4-HO-MET (Metocin) in Rhode Island Legal
• 5-MAPB in Rhode Island Legal
• Blue Lotus (Nymphaea caerulea) in Rhode Island Legal
• Amanita muscaria / Muscimol in Rhode Island Legal

Other compounds in Rhode Island

Cite this page