As of July 18, 2026, Endomorphin-1 is legal to sell at retail in West Virginia. Unscheduled - legal as research-use-only; no operative instrument reaches a structurally-dissimilar opioid peptide. Controlling source: None operative - 'Analogue' def (60A-1-101(c)) non-operative; imitation only.
Verified July 18, 2026 · confidence: confirmedEndomorphin-1 (Tyr-Pro-Trp-Phe-NH2) is not named or scheduled in West Virginia. The state has no chemical analogue statute; only an imitation / counterfeit / misrepresentation offense that turns on appearance or representation, not on a substance's intrinsic structure or effect. Controlling instrument reviewed: None operative - 'Analogue' def (60A-1-101(c)) non-operative; imitation only. Conclusion: no operative instrument reaches a structurally-dissimilar endogenous opioid peptide; status LEGAL at the state controlled-substances level. Residual risk: minimal. Federal floor still applies (Analogue Act human-consumption contingency + FD&C unapproved-new-drug).
W. Va. Code 60A-1-101(c): "'Analogue' means a substance that, in relation to a controlled substance, has a substantially similar chemical structure." This definition carries NO general offense; the only operative catch-all is the representation-based imitation-controlled-substance offense. [Definition non-operative; structure prong would fail regardless.]
Among West Virginia's 5 neighbors, Kentucky, Maryland, Ohio, Pennsylvania and Virginia are legal, the same posture as West Virginia.
Open the interactive map · Every compound in West Virginia
Not federally scheduled. Endomorphin-1 - not federally scheduled; endogenous opioid tetrapeptide, no CSA entry and no analogue-act structural hook Federal detail
1 instrument on file for this compound's framework in West Virginia; 2 of 2 citations above are official sources. Each text carries its source and a fingerprint that changes when the law does.
5a2cf2b4af07cb9e**Named entry (Schedule I, Hallucinogenic substances, "Tryptamines")** — "Tryptamines: 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT); 4-hydroxy-N,N-diisopropyltryptamine (4-HO-DiPT); 4-hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MiPT); **4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET);** 4-acetoxy-N,N-diisopropyltryptamine (4-AcO-DiPT) …" — W. Va. Code § 60A-2-204(d), https://code.wvlegislature.gov/pdf/60A-2-204/ (OFFICIAL — West Virginia Legislature). **Schedule I chapeau (isomer/ester/ether expansion)** — "(a) Schedule I shall consist of the drugs and other substances … including their isomers, esters, ethers, salts and salts of isomers, esters, and ethers, whenever the existence of such isomers, esters, ethers, and salts is possible within the specific chemical designation." — W. Va. Code § 60A-2-204(a). Same URL (OFFICIAL).
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